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Molecular Biology

D-Index
42
Citations
9786
World Ranking
3003
National Ranking
89

Overview

Michal Opas is affiliated with the University of Toronto in Canada and focuses research primarily within the field of Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Cell Biology, Oncology, Genetics, and Cellular and Molecular Neuroscience.

The main topics explored in their research include:

  • Signaling Pathways in Disease
  • Endoplasmic Reticulum Stress and Disease
  • Bone Metabolism and Diseases
  • Genetics and Neurodevelopmental Disorders
  • Cytokine Signaling Pathways and Interactions
  • TGF-β signaling in diseases
  • Peptidase Inhibition and Analysis

Michal Opas has contributed to multiple research publications with a focus on stem cells and osteogenic differentiation. Their recent papers include:

  • Calreticulin regulates a switch between osteoblast and chondrocyte lineages derived from murine embryonic stem cells, 2020, Journal of Biological Chemistry
  • c-Src kinase inhibits osteogenic differentiation via enhancing STAT1 stability, 2020, PLoS ONE
  • Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells, 2020, Stem Cell Research
  • Osteogenic Differentiation from Mouse Embryonic Stem Cells, 2021, Methods in molecular biology

Frequent co-authors collaborating with Michal Opas include:

  • Zahra Alvandi
  • Carlos Pilquil
  • Layla Al-Mansoori

Their work has been published in a variety of scientific venues, such as:

  • Journal of Biological Chemistry
  • PLoS ONE
  • Stem Cell Research
  • Methods in molecular biology

Best Publications

  • Calreticulin: one protein, one gene, many functions.

    Marek Michalak;Elaine F. Corbett;Nasrin Mesaeli;Kimitoshi Nakamura

  • Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum

    Marek Michalak;Jody Groenendyk;Eva Szabo;Leslie I. Gold

  • Calreticulin Is Essential for Cardiac Development

    Nasrin Mesaeli;Kimitoshi Nakamura;Elena Zvaritch;Peter Dickie

  • Ca2+ signaling and calcium binding chaperones of the endoplasmic reticulum

    M Michalak;J.M Robert Parker;M Opas

  • Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis

    Kimitoshi Nakamura;Kimitoshi Nakamura;Ella Bossy-Wetzel;Kimberly Burns;Kimberly Burns;Marc P. Fadel

  • The ins and outs of calreticulin: from the ER lumen to the extracellular space.

    Steven Johnson;Marek Michalak;Michal Opas;Paul Eggleton

  • Functional specialization of calreticulin domains.

    Kimitoshi Nakamura;Anna Zuppini;Serge Arnaudeau;Jeffery Lynch

  • Calreticulin, a Ca2+-binding chaperone of the endoplasmic reticulum.

    Pascal Gelebart;Michal Opas;Marek Michalak

  • Overexpression of Calreticulin Increases Intracellular Ca2+ Storage and Decreases Store-operated Ca2+ Influx (∗)

    Laurence Mery;Nasrin Mesaeli;Marek Michalak;Michal Opas

  • Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, and ERp57.

    Karen Bedard;Eva Szabo;Marek Michalak;Michal Opas

  • Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle cells.

    Michal Opas;Ewa Dziak;Larry Fliegel;Marek Michalak

  • Calreticulin Modulates Cell Adhesiveness via Regulation of Vinculin Expression

    Michal Opas;Malgorzata Szewczenko-Pawlikowski;Greta K. Jass;Nasrin Mesaeli

  • Complete heart block and sudden death in mice overexpressing calreticulin

    Kimitoshi Nakamura;Murray Robertson;Gang Liu;Peter Dickie

  • Endoplasmic Reticulum Form of Calreticulin Modulates Glucocorticoid-sensitive Gene Expression

    Marek Michalak;Kimberly Burns;Christi Andrin;Nasrin Mesaeli

  • Calreticulin: not just another calcium-binding protein.

    Piers D. Nash;Michal Opas;Marek Michalak

  • Expression of the differentiated phenotype by epithelial cells in vitro is regulated by both biochemistry and mechanics of the substratum.

    Michal Opas

  • Cardiac-specific Expression of Calcineurin Reverses Embryonic Lethality in Calreticulin-deficient Mouse

    Lei Guo;Kimitoshi Nakamura;Jeffery Lynch;Michal Opas

  • Calreticulin, a multifunctional Ca2+ binding chaperone of the endoplasmic reticulum.

    Marek Michalak;Paola Mariani;Michal Opas

  • Is all of the endoplasmic reticulum created equal? The effects of the heterogeneous distribution of endoplasmic reticulum Ca2+-handling proteins

    S. Papp;E. Dziak;M. Michalak;M. Opas

  • The high-affinity calcium binding protein of sarcoplasmic reticulum. Tissue distribution, and homology with calregulin.

    Larry Fliegel;Kimberly Burns;Michal Opas;Marek Michalak

Frequent Co-Authors

Marek Michalak
Marek Michalak University of Alberta
Lei Guo
Lei Guo National Center for Toxicological Research
Karl-Heinz Krause
Karl-Heinz Krause University of Geneva
Christopher A. McCulloch
Christopher A. McCulloch University of Toronto
R. Chris Bleackley
R. Chris Bleackley University of Alberta
Larry Fliegel
Larry Fliegel University of Alberta
Elissavet Kardami
Elissavet Kardami University of Manitoba
Nicolas Demaurex
Nicolas Demaurex University of Geneva
Paul Eggleton
Paul Eggleton University of Exeter
Daniel Pablo Lew
Daniel Pablo Lew University of Geneva

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