2026 Lei Guo: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	48	2656	2405	1295	1162	111	19334

Overview

Lei Guo is affiliated with the National Center for Toxicological Research in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions to related subfields such as Molecular Biology, Pharmacology, Oncology, Cancer Research, and Plant Science.

Their work addresses various topics including Pharmacogenetics and Drug Metabolism, Cannabis and Cannabinoid Research, Drug Transport and Resistance Mechanisms, Cancer-related molecular mechanisms research, Cancer therapeutics and mechanisms, CRISPR and Genetic Engineering, and Autophagy in Disease and Therapy.

Lei Guo has published research in a range of scientific venues, most frequently in:

Archives of Toxicology
Journal of Environmental Science and Health Part C
Toxicological Sciences
Chemico-Biological Interactions
Methods in Molecular Biology

Their recent papers include:

The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma (2022) published in Autophagy
The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells (2021) published in Toxicology Letters
Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity (2021) published in Journal of Environmental Science and Health Part C
Roles of CYP3A4, CYP3A5 and CYP2C8 drug-metabolizing enzymes in cellular cytostatic resistance (2021) published in Chemico-Biological Interactions
In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells (2021) published in Food and Chemical Toxicology

The scientist has collaborated frequently with peers including Si Chen, Nan Mei, Yuxi Li, Xilin Li, and Xuan Qin.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

8488
Citations
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

Leming Shi;Laura H. Reid;Wendell D. Jones;Richard Shippy

2470
Citations
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

Zhenqiang Su;Paweł P. Łabaj;Sheng Li;Jean Thierry-Mieg

1015
Citations
Rat toxicogenomic study reveals analytical consistency across microarray platforms

Lei Guo;Edward K Lobenhofer;Charles Wang;Richard Shippy

497
Citations
The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

Leming Shi;Wendell D. Jones;Roderick V. Jensen;Stephen C. Harris

398
Citations
Next-generation sequencing in the clinic: promises and challenges.

Jiekun Xuan;Ying Yu;Tao Qing;Lei Guo

392
Citations
A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages.

Ying Yu;James C. Fuscoe;Chen Zhao;Chao Guo

371
Citations
Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

Lei Guo;Stacey Dial;Leming Shi;William Branham

361
Citations
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

287
Citations
Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential.

Leming Shi;Weida Tong;Hong Fang;Uwe Scherf

254
Citations
Cross-platform comparison of SYBR® Green real-time PCR with TaqMan PCR, microarrays and other gene expression measurement technologies evaluated in the MicroArray Quality Control (MAQC) study

Emi Arikawa;Yanyang Sun;Jie Wang;Qiong Zhou

225
Citations
Review of usnic acid and Usnea barbata toxicity

Lei Guo;Qiang Shi;Jia-Long Fang;Nan Mei

162
Citations
Review of Ginkgo biloba-induced toxicity, from experimental studies to human case reports.

Nan Mei;Xiaoqing Guo;Zhen Ren;Daisuke Kobayashi

147
Citations
Cardiac-specific Expression of Calcineurin Reverses Embryonic Lethality in Calreticulin-deficient Mouse

Lei Guo;Kimitoshi Nakamura;Jeffery Lynch;Michal Opas

141
Citations
Evaluation of external RNA controls for the assessment of microarray performance

Weida Tong;Anne Bergstrom Lucas;Richard Shippy;Xiaohui Fan;Xiaohui Fan

127
Citations
Microarray scanner calibration curves: characteristics and implications

Leming Shi;Weida Tong;Zhenqiang Su;Tao Han

117
Citations
Mitochondrial dysfunction induced by sertraline, an antidepressant agent.

Yan Li;Letha Couch;Masahiro Higuchi;Jia-Long Fang

112
Citations
Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca2+-dependent signaling cascade

Jeffrey Lynch;Lei Guo;Pascal Gelebart;Kaari Chilibeck

111
Citations
Polycystin-2 associates with tropomyosin-1, an actin microfilament component.

Qiang Li;Yue Dai;Lei Guo;Yan Liu

100
Citations
Toxicity of kava kava.

Peter P Fu;Qingsu Xia;Lei Guo;Hongtao Yu

97
Citations

Frequent Co-Authors

Leming Shi Fudan University

Weida Tong National Center for Toxicological Research

Hong Fang National Center for Toxicological Research

Huixiao Hong United States Food and Drug Administration

Marek Michalak University of Alberta

Quan Zhen Li The University of Texas Southwestern Medical Center

Roger Perkins United States Food and Drug Administration

Peter P. Fu United States Food and Drug Administration

Raj K. Puri US Food and Drug Administration

James C. Willey University of Toledo

External Links

Personal website of Lei Guo

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