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Christopher A. McCulloch

Christopher A. McCulloch

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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
97
Citations
29768
World Ranking
1771
National Ranking
52

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

Christopher A. McCulloch is affiliated with the University of Toronto in Canada. Their research spans across several fields primarily within biochemistry, genetics, molecular biology, and medicine. The scientist has contributed extensively to subfields such as cell biology, molecular biology, oral surgery, immunology and allergy, and immunology.

McCulloch's work focuses on topics related to cellular mechanics and interactions, skin and cellular biology research, cell adhesion molecules research, periodontal regeneration and treatments, oral microbiology and periodontitis research, wound healing and treatments, and dental implant techniques and outcomes.

Their recent publications include the following papers:

  • Suppression of the fibrotic encapsulation of silicone implants by inhibiting the mechanical activation of pro-fibrotic TGF-β, 2021, Nature Biomedical Engineering
  • The Neutrophil: Constant Defender and First Responder, 2020, Frontiers in Immunology
  • Impact of Vimentin on Regulation of Cell Signaling and Matrix Remodeling, 2022, Frontiers in Cell and Developmental Biology
  • TRPV4 integrates matrix mechanosensing with Ca2+ signaling to regulate extracellular matrix remodeling, 2020, FEBS Journal
  • Vimentin regulates the assembly and function of matrix adhesions, 2021, Wound Repair and Regeneration

Frequent co-authors collaborating with McCulloch include:

  • Isabel Ding
  • Yongqiang Wang
  • Zofia Ostrowska-Podhorodecka
  • Chenfan Ji
  • Paul A. Janmey

McCulloch has published multiple articles in well-known scientific journals and publication venues. The most common venues for their work include:

  • The FASEB Journal
  • Frontiers in Dental Medicine
  • Journal of Cell Science
  • Journal of Cellular Physiology
  • Dentistry Journal

Best Publications

  • Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.

    G. Angus McQuibban;Jiang-Hong Gong;Eric M. Tam;Christopher A. G. McCulloch

  • Cell Mechanics: Integrating Cell Responses to Mechanical Stimuli

    Paul A. Janmey;Christopher A. McCulloch

  • The compliance of collagen gels regulates transforming growth factor-β induction of α-smooth muscle actin in fibroblasts

    Pamela D. Arora;Nazanin Narani;Christopher A.G. McCulloch

  • Tissue engineering: a new paradigm for periodontal regeneration based on molecular and cell biology.

    P. M. Bartold;C. A. G. McCulloch;A. S. Narayanan;S. Pitaru

  • Reproducibility and Sensitivity of Oral Malodor Measurements with a Portable Sulphide Monitor

    M. Rosenberg;G.V. Kulkarni;A. Bosy;C.A.G. McCulloch

  • Relationship of Oral Malodor to Periodontitis: Evidence of Independence in Discrete Subpopulations

    A. Bosy;G. V. Kulkarni;M. Rosenberg;C.A.G. McCulloch

  • Measurement of oral malodor: current methods and future prospects.

    Mel Rosenberg;Christopher A. G. McCulloch

  • Role of fibroblast subpopulations in periodontal physiology and pathology.

    Christopher A. G. McCulloch;Sandra Bordin

  • Periodontal ligament cell populations: The central role of fibroblasts in creating a unique tissue

    P. Lekic;C.A.G. McCulloch

  • Dependence of collagen remodelling on alpha-smooth muscle actin expression by fibroblasts

    Pamela D. Arora;Christopher A. G. McCulloch

  • Force activates smooth muscle α-actin promoter activity through the Rho signaling pathway

    Xiao-Han Zhao;Carol Laschinger;Pam Arora;Katalin Szászi

  • Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: role of active enzyme in human periodontitis.

    W. Lee;S. Aitken;J. Sodek;C. A. G. McCulloch

  • Central role for Rho in TGF-β1-induced α-smooth muscle actin expression during epithelial-mesenchymal transition

    András Masszi;András Masszi;Caterina Di Ciano;Gábor Sirokmány;William T. Arthur

  • Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration.

    R. Zohar;N. Suzuki;K. Suzuki;P. Arora

  • Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts

    Jiaxu Wang;Honghong Chen;Arun Seth;Christopher A. McCulloch

  • Integrity of Cell-Cell Contacts Is a Critical Regulator of TGF-β1-Induced Epithelial-to-Myofibroblast Transition : Role for β-Catenin

    András Masszi;Lingzhi Fan;László Rosivall;László Rosivall;Christopher A. McCulloch

  • Osteopontin Expression Is Required for Myofibroblast Differentiation

    Yair Lenga;Adeline Koh;Aruni Shamalee Perera;Christopher A. McCulloch

  • The Role of Actin-binding Protein 280 in Integrin-dependent Mechanoprotection

    Michael Glogauer;Pam Arora;Deborah Chou;Paul A. Janmey

  • Multifunctional roles of gelsolin in health and diseases

    Guo Hua Li;Pamela D. Arora;Yu Chen;Christopher A. McCulloch

  • The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness

    Jinyi Zhang;Naima Zahir;Qiuhong Jiang;Helen Miliotis

Frequent Co-Authors

Jaro Sodek
Jaro Sodek University of Toronto
Gregory P. Downey
Gregory P. Downey National Jewish Health
Michael Glogauer
Michael Glogauer University of Toronto
Paul A. Janmey
Paul A. Janmey University of Pennsylvania
Christopher M. Overall
Christopher M. Overall University of British Columbia
Andras Kapus
Andras Kapus University of Toronto
Boris Hinz
Boris Hinz University of Toronto
Katherine A. Siminovitch
Katherine A. Siminovitch Lunenfeld-Tanenbaum Research Institute
Donald Gullberg
Donald Gullberg University of Bergen
Arun Seth
Arun Seth Sunnybrook Health Science Centre

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