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Biology and Biochemistry

D-Index
55
Citations
9450
World Ranking
15197
National Ranking
6355

Overview

Amar B. Singh is affiliated with the University of Nebraska Medical Center in the United States. Their research focuses primarily on fields related to medicine and biochemistry, genetics, and molecular biology. Among the main subfields of their work are molecular biology, oncology, genetics, neurology, and epidemiology.

Their publications reveal concentrated study into topics such as gut microbiota and health, barrier structure and function, inflammatory bowel disease, cancer cells and metastasis, pancreatic and hepatic oncology research, diet and metabolism studies, and cancer genomics and diagnostics.

Notable recent papers authored or co-authored by Amar B. Singh include:

  • "Gut Microbiota and Metabolic Specificity in Ulcerative Colitis and Crohn's Disease," 2020, Frontiers in Medicine
  • "Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis," 2020, Oncogene
  • "Inflammatory bowel disease: Therapeutic limitations and prospective of the stem cell therapy," 2020, World Journal of Stem Cells
  • "Pancreatic Cancer and Therapy: Role and Regulation of Cancer Stem Cells," 2021, International Journal of Molecular Sciences
  • "Mucosal healing and inflammatory bowel disease: Therapeutic implications and new targets," 2023, World Journal of Gastroenterology

The frequent co-authors who have collaborated with Singh include Punita Dhawan, Rizwan Ahmad, Balawant Kumar, Iram Fatima, and Geoffrey A. Talmon. These collaborations indicate a network spanning multiple areas within biological and medical research.

Singh's most frequent publication venues are Gastroenterology, Cells, SSRN Electronic Journal, World Journal of Gastroenterology, and Oncogene. This indicates their active engagement with journals focused on clinical and molecular research.

The body of work demonstrates an intersection between fundamental molecular studies and applied medical research, particularly in digestive system diseases and oncology. Their research outputs contribute to understanding complex disease mechanisms including inflammatory bowel conditions and pancreatic cancer by exploring biological processes like stemness, mucosal healing, and cancer metastasis.

Best Publications

  • Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

    Punita Dhawan;Amar B. Singh;Natasha G. Deane;Yi Ran No

  • Autocrine, paracrine and juxtacrine signaling by EGFR ligands

    Amar B. Singh;Raymond C. Harris

  • CSF-1 signaling mediates recovery from acute kidney injury

    Ming Zhi Zhang;Bing Yao;Shilin Yang;Li Jiang

  • Constitutive Activation of Akt/Protein Kinase B in Melanoma Leads to Up-Regulation of Nuclear Factor-κB and Tumor Progression

    Punita Dhawan;Amar B. Singh;Darrel L. Ellis;Ann Richmond

  • Claudin Family of Proteins and Cancer: An Overview

    Amar B. Singh;Ashok Sharma;Punita Dhawan

  • Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling

    Jillian L. Pope;Ajaz Ahmad Bhat;Ashok Sharma;Rizwan Ahmad

  • Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells.

    Amar B. Singh;Rayrnond C. Harris

  • Gut permeability and mucosal inflammation: bad, good or context dependent.

    R Ahmad;M F Sorrell;S K Batra;P Dhawan

  • Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury

    Gur P. Kaushal;Amar B. Singh;Sudhir V. Shah

  • Claudin-1 Up-regulates the Repressor ZEB-1 to Inhibit E-Cadherin Expression in Colon Cancer Cells

    Amar B. Singh;Ashok Sharma;J. Joshua Smith;Moorthy Krishnan

  • Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.

    P Dhawan;R Ahmad;R Chaturvedi;J J Smith

  • Pyranocoumarins: A new class of anti-hyperglycemic and anti-dyslipidemic agents

    Atul Kumar;Ram Awatar Maurya;Siddharth Sharma;Pervez Ahmad

  • The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology

    Fenghua Zeng;Amar B. Singh;Raymond C. Harris

  • Inhibition of PCSK9 Transcription by Berberine Involves Down-regulation of Hepatic HNF1α Protein Expression through the Ubiquitin-Proteasome Degradation Pathway

    Bin Dong;Hai Li;Amar Bahadur Singh;Aiqin Cao

  • Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis.

    R Ahmad;R Chaturvedi;D Olivares-Villagómez;T Habib

  • Smad4 Regulates Claudin-1 Expression in a Transforming Growth Factor-β–Independent Manner in Colon Cancer Cells

    Sheng Ru Shiou;Amar B. Singh;Krishnan Moorthy;Pran K. Datta

  • Methoxylated isoflavones, cajanin and isoformononetin, have non-estrogenic bone forming effect via differential mitogen activated protein kinase (MAPK) signaling.

    Biju Bhargavan;Abnish Kumar Gautam;Divya Singh;Amit Kumar

  • Integrin α1β1 Controls Reactive Oxygen Species Synthesis by Negatively Regulating Epidermal Growth Factor Receptor-Mediated Rac Activation

    Xiwu Chen;Tristin D. Abair;Maria R. Ibanez;Yan Su

  • Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching

    Rizwan Ahmad;Bilal Rah;Dhundy Bastola;Punita Dhawan

  • Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia.

    Anna L. Means;Kevin C. Ray;Amar B. Singh;M.Kay Washington

Frequent Co-Authors

Raymond C. Harris
Raymond C. Harris Vanderbilt University Medical Center
Keith T. Wilson
Keith T. Wilson Vanderbilt University Medical Center
Rupesh Chaturvedi
Rupesh Chaturvedi Jawaharlal Nehru University
Roy Zent
Roy Zent Vanderbilt University Medical Center
Xi Chen
Xi Chen University of California, Davis
J. Joshua Smith
J. Joshua Smith Memorial Sloan Kettering Cancer Center
Surinder K. Batra
Surinder K. Batra University of Nebraska Medical Center
Ambra Pozzi
Ambra Pozzi Vanderbilt University Medical Center
Geoffrey M. Thiele
Geoffrey M. Thiele University of Nebraska Medical Center
Naibedya Chattopadhyay
Naibedya Chattopadhyay Central Drug Research Institute

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