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Biology and Biochemistry

D-Index
71
Citations
14830
World Ranking
6787
National Ranking
453

Overview

Norimasa Sawada is affiliated with Sapporo Medical University in Japan. Their research spans multiple aspects of medicine, with a particular focus on cancer biology and molecular mechanisms underlying disease processes.

The scientist's recent publications cover diverse topics, including cancer progression, cellular signaling, and tissue barrier functions. Notable papers include:

  • Aldolase A promotes epithelial-mesenchymal transition to increase malignant potentials of cervical adenocarcinoma, 2020, Cancer Science
  • Elevated expression of G protein-coupled receptor 30 (GPR30) is associated with poor prognosis in patients with uterine cervical adenocarcinoma, 2020, PubMed
  • Emerging roles of transmembrane-type tight junction proteins in cancers, 2023, Pathology International
  • Cholangio-venous reflux of biliary contents through paracellular pathways between hepatocytes in patients with acute cholangitis, 2021, Journal of Hepato-Biliary-Pancreatic Sciences

Norimasa Sawada collaborates frequently with several researchers, including:

  • Akira Takasawa
  • Kumi Takasawa
  • Masaki Murata
  • Makoto Osanai
  • Tomoyuki Aoyama

Their work is published in various scientific venues, among which the most frequent include:

  • Cancer Science
  • Pathology International
  • PubMed
  • Journal of Hepato-Biliary-Pancreatic Sciences

Norimasa Sawada's primary fields of study are Medicine and Biochemistry, Genetics and Molecular Biology. The subfields reflect their specialized research interests and include:

  • Cancer Research
  • Oncology
  • Molecular Biology
  • Neurology
  • Cell Biology

The main topics addressed in their research cover:

  • Cancer, Hypoxia, and Metabolism
  • Cancer Cells and Metastasis
  • Epigenetics and DNA Methylation
  • Barrier Structure and Function Studies
  • Cancer-related molecular mechanisms research
  • Caveolin-1 and cellular processes
  • Estrogen and related hormone effects

This profile reflects the research orientations and academic contributions made by Norimasa Sawada based on their publication record and collaborations within the biomedical sciences.

Best Publications

  • Transmembrane proteins of tight junctions.

    Hideki Chiba;Makoto Osanai;Masaki Murata;Takashi Kojima

  • Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations.

    B. L. Kreamer;J. L. Staecker;N. Sawada;G. L. Sattler

  • Tight junctions and human diseases.

    Norimasa Sawada;Masaki Murata;Keisuke Kikuchi;Makoto Osanai

  • Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.

    Hiroki Fujita;Kotaro Sugimoto;Shuichiro Inatomi;Toshihiro Maeda

  • Glial cell line-derived neurotrophic factor induces barrier function of endothelial cells forming the blood-brain barrier.

    Yo Igarashi;Hiroyuki Utsumi;Hideki Chiba;Yumiko Yamada-Sasamori

  • Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells

    Kunihiko Nagasawa;Hideki Chiba;Hiroki Fujita;Takashi Kojima

  • Differential Expression and Subcellular Localization of Claudin-7, −8, −12, −13, and −15 Along the Mouse Intestine

    Hiroki Fujita;Hideki Chiba;Hiroshi Yokozaki;Naoyuki Sakai

  • Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood–brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways

    Tsutomu Ishizaki;Hideki Chiba;Takashi Kojima;Masato Fujibe

  • Tight junction-related human diseases.

    Norimasa Sawada

  • Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells.

    Tamaki Okabayashi;Takashi Kojima;Tomoyuki Masaki;Shin-ichi Yokota

  • Hepatic iron deprivation prevents spontaneous development of fulminant hepatitis and liver cancer in Long-Evans Cinnamon rats.

    Junji Kato;Masayoshi Kobune;Yutaka Kohgo;Naoki Sugawara

  • Reduced expression of claudin-7 correlates with invasion and metastasis in squamous cell carcinoma of the esophagus.

    Yu Usami;Hideki Chiba;Fumihito Nakayama;Junya Ueda

  • HLA-DR- and CD11c-positive dendritic cells penetrate beyond well-developed epithelial tight junctions in human nasal mucosa of allergic rhinitis.

    Ken-ichi Takano;Takashi Kojima;Mitsuru Go;Masaki Murata

  • Thr203 of claudin-1, a putative phosphorylation site for MAP kinase, is required to promote the barrier function of tight junctions.

    Masato Fujibe;Hideki Chiba;Takashi Kojima;Tamotsu Soma

  • The role of IL‐33 and its receptor ST2 in human nasal epithelium with allergic rhinitis

    R. Kamekura;T. Kojima;K. Takano;M. Go

  • Occludin expression decreases with the progression of human endometrial carcinoma.

    Hirotoshi Tobioka;Hiroshi Isomura;Yasuo Kokai;Yuichi Tokunaga

  • Thr207 of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP

    Tamotsu Soma;Hideki Chiba;Yuko Kato-Mori;Takuro Wada

  • Regulation of Tight Junctions in Upper Airway Epithelium

    Takashi Kojima;Mitsuru Go;Ken-ichi Takano;Makoto Kurose

  • ErbB2 expression is correlated with increased survival of patients with osteosarcoma.

    Tomohiro Akatsuka;Takuro Wada M.D.;Yasuo Kokai M.D.;Satoshi Kawaguchi M.D.

  • Epigenetic Silencing of Occludin Promotes Tumorigenic and Metastatic Properties of Cancer Cells via Modulations of Unique Sets of Apoptosis-Associated Genes

    Makoto Osanai;Masaki Murata;Nami Nishikiori;Hideki Chiba

Frequent Co-Authors

Takashi Kojima
Takashi Kojima Sapporo Medical University
Hideki Chiba
Hideki Chiba Fukushima Medical University
Koichi Hirata
Koichi Hirata Sapporo Medical University
Nobuhiro Fujii
Nobuhiro Fujii Sapporo Medical University
Hiroshi Yokozaki
Hiroshi Yokozaki Kobe University
David C. Spray
David C. Spray Albert Einstein College of Medicine
Yoshio Kuroki
Yoshio Kuroki Sapporo Medical University
Yoshihiko Hirohashi
Yoshihiko Hirohashi Sapporo Medical University
Noriyuki Sato
Noriyuki Sato Sapporo Medical University
Takashi Tokino
Takashi Tokino Sapporo Medical University

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