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Yoshihiko Hirohashi

Yoshihiko Hirohashi

Sapporo Medical University
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
8122
World Ranking
18065
National Ranking
1302

Yoshihiko Hirohashi publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Yoshihiko Hirohashi sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 274 publications — 73rd percentile

73% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Yoshihiko Hirohashi D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Yoshihiko Hirohashi sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 49 D-Index — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Yoshihiko Hirohashi is affiliated with Sapporo Medical University in Japan and primarily conducts research in the fields of Medicine and Immunology and Microbiology. Their work spans several subfields, including Oncology, Immunology, Molecular Biology, Cancer Research, and Surgery.

The main topics addressed in Hirohashi's research focus on Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, CAR-T cell therapy research, Bladder and Urothelial Cancer Treatments, Cancer Cells and Metastasis, and T-cell and B-cell Immunology.

Frequent coauthors collaborating with Hirohashi include:

  • Toshihiko Torigoe
  • Takayuki Kanaseki
  • Tomohide Tsukahara
  • Terufumi Kubo
  • Kenji Murata

Hirohashi often publishes in several academic journals and venues, with the most frequent including:

  • Anticancer Research
  • Cancer Science
  • Medical Molecular Morphology
  • Immunological Medicine
  • Cancer Immunology Immunotherapy

Selected recent papers by Hirohashi illustrate the scope of their work:

  • "Aldolase A promotes epithelial-mesenchymal transition to increase malignant potentials of cervical adenocarcinoma" (2020, Cancer Science)
  • "A screening assistance system for cervical cytology of squamous cell atypia based on a two-step combined CNN algorithm with label smoothing" (2021, Cancer Medicine)
  • "CD8+ T-cell Immune Surveillance against a Tumor Antigen Encoded by the Oncogenic Long Noncoding RNA PVT1" (2021, Cancer Immunology Research)
  • "Association between radiotherapy-induced alteration of programmed death ligand 1 and survival in patients with uterine cervical cancer undergoing preoperative radiotherapy" (2020, Strahlentherapie und Onkologie)
  • "Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch repair-deficient colorectal cancer tissue" (2021, JCI Insight)

Best Publications

  • Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells.

    Hiroko Asanuma;Toshihiko Torigoe;Kenjiro Kamiguchi;Yoshihiko Hirohashi

  • An HLA-A24-restricted Cytotoxic T Lymphocyte Epitope of a Tumor-associated Protein, Survivin

    Yoshihiko Hirohashi;Toshihiko Torigoe;Akiko Maeda;Yuki Nabeta

  • Aberrant Expression and Potency as a Cancer Immunotherapy Target of Inhibitor of Apoptosis Protein Family, Livin/ML-IAP in Lung Cancer

    Hiroyuki Hariu;Yoshihiko Hirohashi;Toshihiko Torigoe;Hiroko Asanuma

  • Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer

    Tetsuhiro Tsuruma;Fumitake Hata;Toshihiko Torigoe;Tomohisa Furuhata

  • Detection of autoantibodies to livin and survivin in Sera from lung cancer patients.

    Atsuhito Yagihashi;Koichi Asanuma;Daisuke Kobayashi;Naoki Tsuji

  • A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins

    Satomi Idenoue;Yoshihiko Hirohashi;Toshihiko Torigoe;Yuriko Sato

  • Preferential expression of cancer/testis genes in cancer stem-like cells: proposal of a novel sub-category, cancer/testis/stem gene.

    R. Yamada;A. Takahashi;T. Torigoe;R. Morita

  • Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients.

    Jun-ichi Kobayashi;Toshihiko Torigoe;Yoshihiko Hirohashi;Satomi Idenoue

  • Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells.

    Satoko Inoda;Yoshihiko Hirohashi;Toshihiko Torigoe;Rena Morita

  • HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem-like Cells

    Satoshi Nishizawa;Yoshihiko Hirohashi;Toshihiko Torigoe;Akari Takahashi

  • SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

    Munehide Nakatsugawa;Akari Takahashi;Yoshihiko Hirohashi;Toshihiko Torigoe

  • ALDH1-High Ovarian Cancer Stem-Like Cells Can Be Isolated from Serous and Clear Cell Adenocarcinoma Cells, and ALDH1 High Expression Is Associated with Poor Prognosis

    Takafumi Kuroda;Yoshihiko Hirohashi;Toshihiko Torigoe;Kazuyo Yasuda

  • Efficient Cross-Presentation by Heat Shock Protein 90-Peptide Complex-Loaded Dendritic Cells via an Endosomal Pathway

    Takehiro Kurotaki;Yasuaki Tamura;Gosei Ueda;Gosei Ueda;Jun Oura

  • Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma.

    Satoko Inoda;Yoshihiko Hirohashi;Toshihiko Torigoe;Munehide Nakatsugawa

  • Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer

    Tetsuhiro Tsuruma;Yuji Iwayama;Tosei Ohmura;Tadashi Katsuramaki

  • Immune responses to human cancer stem-like cells/cancer-initiating cells.

    Yoshihiko Hirohashi;Toshihiko Torigoe;Tomohide Tsukahara;Takayuki Kanaseki

  • Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients.

    Hidekazu Kameshima;Tetsuhiro Tsuruma;Goro Kutomi;Hiroaki Shima

  • Detection and induction of CTLs specific for SYT-SSX-derived peptides in HLA-A24(+) patients with synovial sarcoma.

    Yuriko Sato;Yuki Nabeta;Tomohide Tsukahara;Yoshihiko Hirohashi

  • Identification of human autologous cytotoxic T-lymphocyte-defined osteosarcoma gene that encodes a transcriptional regulator, papillomavirus binding factor.

    Tomohide Tsukahara;Yuki Nabeta;Satoshi Kawaguchi;Hideyuki Ikeda

  • Ovarian Cancer Stem Cells Are Enriched in Side Population and Aldehyde Dehydrogenase Bright Overlapping Population

    Kazuyo Yasuda;Toshihiko Torigoe;Rena Morita;Takahumi Kuroda

Frequent Co-Authors

Toshihiko Torigoe
Toshihiko Torigoe Sapporo Medical University
Noriyuki Sato
Noriyuki Sato Sapporo Medical University
Koichi Hirata
Koichi Hirata Sapporo Medical University
Mark I. Greene
Mark I. Greene University of Pennsylvania
Takashi Tokino
Takashi Tokino Sapporo Medical University
Kohzoh Imai
Kohzoh Imai University of Tokyo
Hongtao Zhang
Hongtao Zhang University of Pennsylvania
Akiko Maeda
Akiko Maeda Case Western Reserve University
Minoru Toyota
Minoru Toyota Sapporo Medical University
Norimasa Sawada
Norimasa Sawada Sapporo Medical University

External Links

Personal website of Yoshihiko Hirohashi

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For students seeking affordable pathways, consider affordable online him programs or the cheapest online nutrition degree options. These programs not only reduce financial strain but also prepare graduates for high-demand sectors in health data management and nutrition science.

Best Scientists Citing Yoshihiko Hirohashi

Toshihiko Torigoe

Toshihiko Torigoe

Sapporo Medical University

Publications: 46

Noriyuki Sato

Noriyuki Sato

Sapporo Medical University

Publications: 43

Soldano Ferrone

Soldano Ferrone

Harvard University

Publications: 12

Jianlin Gong

Jianlin Gong

Boston University

Publications: 10

Stuart K. Calderwood

Stuart K. Calderwood

Beth Israel Deaconess Medical Center

Publications: 10

Koichi Hirata

Koichi Hirata

Sapporo Medical University

Publications: 9

Michael R. Hamblin

Michael R. Hamblin

University of Johannesburg

Publications: 9

Masaki Mori

Masaki Mori

Kyushu University

Publications: 8

Dario C. Altieri

Dario C. Altieri

The Wistar Institute

Publications: 8

Francesco M. Marincola

Francesco M. Marincola

National Institutes of Health

Publications: 8

Barbara Seliger

Barbara Seliger

Martin Luther University Halle-Wittenberg

Publications: 7

Yusuke Nakamura

Yusuke Nakamura

National Institutes of Biomedical Innovation, Health and Nutrition

Publications: 7

Peter J. van den Elsen

Peter J. van den Elsen

Leiden University Medical Center

Publications: 7

Hans-Georg Rammensee

Hans-Georg Rammensee

University of Tübingen

Publications: 7

Jérôme Galon

Jérôme Galon

Inserm

Publications: 7

Bernard A. FoxEarle

Bernard A. FoxEarle

Earle A. Chiles Research Institute

Publications: 7

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