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Hiroshi Yokozaki

Hiroshi Yokozaki

D-Index & Metrics

Medicine

D-Index
83
Citations
18928
World Ranking
15817
National Ranking
492

Overview

Hiroshi Yokozaki is affiliated with Kobe University in Japan, focusing primarily on medical and biochemical scientific research. Their work spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with special attention to subfields such as Molecular Biology, Immunology, Oncology, Cancer Research, and Pulmonary and Respiratory Medicine.

The main topics explored in their research include:

  • Immune cells in cancer
  • Cancer Cells and Metastasis
  • Cancer-related molecular mechanisms research
  • Chemokine receptors and signaling
  • RNA modifications and cancer
  • Immune Cell Function and Interaction
  • Gastric Cancer Management and Outcomes

Yokozaki has contributed to multiple scientific publications, especially in well-established journals and conference proceedings. Frequent venues for their work include:

  • Pathology International
  • American Journal Of Pathology
  • Cancers
  • Preprints.org
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society

Their recent papers reflect a focus on signaling pathways, cancer cell migration and invasion, and molecular mechanisms in esophageal and gastric cancers. Notable publications include:

  • CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways, 2020, Laboratory Investigation
  • PAI-1 derived from cancer-associated fibroblasts in esophageal squamous cell carcinoma promotes the invasion of cancer cells and the migration of macrophages, 2020, Laboratory Investigation
  • S100A8/A9 Induced by Interaction with Macrophages in Esophageal Squamous Cell Carcinoma Promotes the Migration and Invasion of Cancer Cells via Akt and p38 MAPK Pathways, 2021, American Journal Of Pathology
  • Growth Differentiation Factor 15 Promotes Progression of Esophageal Squamous Cell Carcinoma via TGF-β Type II Receptor Activation, 2020, Pathobiology
  • Molecular Network Profiling in Intestinal- and Diffuse-Type Gastric Cancer, 2020, Cancers

Throughout Yokozaki's work, collaboration with several frequent coauthors is evident, including:

  • Yu-ichiro Koma
  • Mari Nishio
  • Manabu Shigeoka
  • Takayuki Kodama
  • Sabina Quader

Their body of research spans multiple aspects of cancer biology, emphasizing molecular and cellular mechanisms underlying cancer progression and immune cell interactions in the tumor microenvironment. The focus on pathways such as Akt, ERK, and p38 MAPK illustrates a molecular approach to understanding cancer metastasis and potential therapeutic targets.

Best Publications

  • Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.

    Hiroki Fujita;Kotaro Sugimoto;Shuichiro Inatomi;Toshihiro Maeda

  • Frequent amplification of the c-met gene in scirrhous type stomach cancer.

    Hiroki Kuniyasu;Wataru Yasui;Yasuhiko Kitadai;Hiroshi Yokozaki

  • Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer

    Hiroki Kuniyasu;Hiroki Kuniyasu;Naohide Oue;Atsuko Wakikawa;Hideo Shigeishi

  • Expression of interleukin-8 correlates with vascularity in human gastric carcinomas.

    Yasuhiko Kitadai;Ken Haruma;Koji Sumii;Soichiro Yamamoto

  • Interaction of Oxidative Stress and Inflammatory Response in Coronary Plaque Instability: Important Role of C-Reactive Protein

    Seiichi Kobayashi;Nobutaka Inoue;Yoshitaka Ohashi;Mitsuyoshi Terashima

  • Co‐expression of osteopontin and CD44v9 in gastric cancer

    Teruyoshi Ue;Hiroshi Yokozaki;Yasuhiko Kitadai;Soichiro Yamamoto

  • Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer

    Yasuko Matsukawa;Shuho Semba;Hirotaka Kato;Akihiko Ito

  • Differential Expression and Subcellular Localization of Claudin-7, −8, −12, −13, and −15 Along the Mouse Intestine

    Hiroki Fujita;Hideki Chiba;Hiroshi Yokozaki;Naoyuki Sakai

  • Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.

    Hidetoshi Tahara;Hiroki Kuniyasu;Hiroshi Yokozaki;Wataru Yasui

  • High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases.

    Hirotaka Kato;Shuho Semba;Upik A. Miskad;Yasushi Seo

  • Interaction between epidermal growth factor and its receptor in progression of human gastric carcinoma.

    Wataru Yasui;Jotaro Hata;Hiroshi Yokozaki;Hiroshi Nakatani

  • Frequent Amplification of the Cyclin E Gene in Human Gastric Carcinomas

    Yoshihiko Akama;Wataru Yasui;Hiroshi Yokozaki;Hiroki Kuniyasu

  • Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas.

    Wataru Yasui;Yasusei Kudo;Shuho Semba;Hiroshi Yokozaki

  • Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma.

    Manabu Shigeoka;Naoki Urakawa;Tetsu Nakamura;Mari Nishio

  • Molecular characteristics of eight gastric cancer cell lines established in Japan

    Hiroshi Yokozaki

  • Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice

    Y. Kitadai;Y. Takahashi;K. Haruma;K. Naka

  • Possible role of brain-derived neurotrophic factor in the pathogenesis of coronary artery disease

    Junya Ejiri;Nobutaka Inoue;Seiichi Kobayashi;Rio Shiraki

  • Reduced expression of nm23 is associated with metastasis of human gastric carcinomas.

    Hirofumi Nakayama;Wataru Yasui;Hiroshi Yokozaki;Eiichi Tahara

  • Snail-associated epithelial-mesenchymal transition promotes oesophageal squamous cell carcinoma motility and progression.

    Y Usami;S Satake;F Nakayama;M Matsumoto

  • Reduced expression of claudin-7 correlates with invasion and metastasis in squamous cell carcinoma of the esophagus.

    Yu Usami;Hideki Chiba;Fumihito Nakayama;Junya Ueda

Frequent Co-Authors

Wataru Yasui
Wataru Yasui Hiroshima University
Eiichi Tahara
Eiichi Tahara Hiroshima University
Yasuhiko Kitadai
Yasuhiko Kitadai Prefectural University of Hiroshima
Akihiko Ito
Akihiko Ito Kindai University
Ken Haruma
Ken Haruma Hiroshima University
Masato Kasuga
Masato Kasuga National Center For Global Health and Medicine
Hidetoshi Tahara
Hidetoshi Tahara Hiroshima University
Hideki Chiba
Hideki Chiba Fukushima Medical University
Norimasa Sawada
Norimasa Sawada Sapporo Medical University
Takeshi Azuma
Takeshi Azuma Kobe University

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