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Etienne Patin

Etienne Patin

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
10642
World Ranking
12146
National Ranking
439

Overview

Etienne Patin is affiliated with the Institut Pasteur in France, focusing on research at the intersection of genetics, molecular biology, immunology, and infectious diseases. Their scholarly output spans main fields such as Biochemistry, Genetics and Molecular Biology and Medicine, with a dominant emphasis on Genetics and Molecular Biology as subfields. The work also encompasses Immunology, Infectious Diseases, and Public Health.

Their research addresses a variety of topics, including forensic and genetic research, immune cell function and interaction, and T-cell and B-cell immunology. Additional areas of focus involve genetic associations and epidemiology, gut microbiota and health, genetic diversity and population structure, and studies related to Yersinia bacterium, plague, and ectoparasites.

Etienne Patin has contributed to numerous recent publications. Notable papers include:

  • Genomic insights into population history and biological adaptation in Oceania, 2021, Nature
  • Smoking changes adaptive immunity with persistent effects, 2024, Nature
  • Human ancient DNA analyses reveal the high burden of tuberculosis in Europeans over the last 2,000 years, 2021, The American Journal of Human Genetics
  • Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe, 2023, Cell Genomics
  • Negative selection on human genes underlying inborn errors depends on disease outcome and both the mode and mechanism of inheritance, 2021, Proceedings of the National Academy of Sciences

Frequent coauthors in Patin's research include Lluís Quintana-Murci, Darragh Duffy, Matthew L. Albert, Laurent Abel, and Bruno Charbit. These collaborations have been significant in advancing various aspects of their work.

Patin's work is often published in specific scholarly venues. The most frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), Nature, The American Journal of Human Genetics, Proceedings of the National Academy of Sciences, and Current Biology. These venues reflect the multidisciplinary nature of the research and its relevance across genetics, immunology, and broader biomedical sciences.

Best Publications

  • Natural selection has driven population differentiation in modern humans

    Luis B Barreiro;Guillaume Laval;Hélène Quach;Etienne Patin

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations.

    Hélène Quach;Maxime Rotival;Maxime Rotival;Julien Pothlichet;Julien Pothlichet;Yong-Hwee Eddie Loh;Yong-Hwee Eddie Loh

  • Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

    Luis B. Barreiro;Luis B. Barreiro;Meriem Ben-Ali;Hélène Quach;Guillaume Laval

  • Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

    Etienne Patin;Milena Hasan;Jacob Bergstedt;Vincent Rouilly

  • The human gene damage index as a gene-level approach to prioritizing exome variants

    Yuval Itan;Lei Shang;Bertrand Boisson;Etienne Patin;Etienne Patin

  • Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.

    Matthieu Deschamps;Guillaume Laval;Maud Fagny;Maud Fagny;Maud Fagny;Yuval Itan

  • Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America

    Etienne Patin;Etienne Patin;Marie Lopez;Marie Lopez;Rebecca Grollemund;Rebecca Grollemund;Paul Verdu

  • Maternal Traces of Deep Common Ancestry and Asymmetric Gene Flow Between Pygmy Hunter-Gatherers and Bantu-speaking Farmers

    Lluís Quintana-Murci;Hélène Quach;Christine Harmant;Francesca Luca

  • Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

    Barbara Piasecka;Darragh Duffy;Alejandra Urrutia;Alejandra Urrutia;Helene Quach

  • Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set.

    Etienne Patin;Guillaume Laval;Luis B. Barreiro;Antonio Salas

  • Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection

    Etienne Patin;Etienne Patin;Zoltán Kutalik;Zoltán Kutalik;Julien Guergnon;Stéphanie Bibert

  • Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

    Petar Scepanovic;Petar Scepanovic;Cécile Alanio;Christian Hammer;Christian Hammer;Christian Hammer;Flavia Hodel;Flavia Hodel

  • Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

    Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Noe Ramirez-Alejo;Zhi Li;Zhi Li;Etienne Patin;Etienne Patin

  • Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia.

    Alexandre Bolze;Alexandre Bolze;Nizar Mahlaoui;Minji Byun;Bridget Turner

  • Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians.

    Chalisa Louicharoen;Chalisa Louicharoen;Etienne Patin;Richard Paul;Issarang Nuchprayoon

  • Evolutionary genetic dissection of human interferons

    Jérémy Manry;Jérémy Manry;Guillaume Laval;Guillaume Laval;Etienne Patin;Etienne Patin;Simona Fornarino;Simona Fornarino

  • Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

    Rubén Martínez-Barricarte;Janet G. Markle;Cindy S. Ma;Elissa K. Deenick

  • IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes†‡§

    Pierre-Yves Bochud;Stéphanie Bibert;Zoltán Kutalik;Zoltán Kutalik;Etienne Patin;Etienne Patin

  • Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

    Amandine Crequer;Anja Troeger;Etienne Patin;Cindy S. Ma

Frequent Co-Authors

Lluis Quintana-Murci
Lluis Quintana-Murci Institut Pasteur
Laurent Abel
Laurent Abel Université Paris Cité
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Luis B. Barreiro
Luis B. Barreiro University of Chicago
Darragh Duffy
Darragh Duffy Institut Pasteur
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Jacques Fellay
Jacques Fellay École Polytechnique Fédérale de Lausanne
Bertrand Boisson
Bertrand Boisson Rockefeller University

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