His main research concerns Virology, Virus, Vaccinia, Antigen and Poxviridae. His work deals with themes such as Immunodominance and Immunogenicity, which intersect with Virology. David C. Tscharke usually deals with Virus and limits it to topics linked to Gene and Cell culture and Glycoprotein.
His research integrates issues of Herpes simplex virus and Cell biology in his study of Antigen. His Poxviridae research also works with subjects such as
David C. Tscharke mainly investigates Virology, Vaccinia, Virus, Cytotoxic T cell and Immunology. David C. Tscharke has researched Virology in several fields, including Immunodominance, T cell, Antigen, Immunogenicity and Epitope. The Immunodominance study combines topics in areas such as Virus antigen and Modified vaccinia Ankara.
His Vaccinia study improves the overall literature in Genetics. The various areas that David C. Tscharke examines in his Virus study include Molecular biology and Gene, Mutant, Virulence. His Cytotoxic T cell research includes elements of Priming, CD8 and T-cell receptor.
The scientist’s investigation covers issues in Virology, Cytotoxic T cell, Epitope, T cell and Immune system. David C. Tscharke studies Virology, focusing on Herpes simplex virus in particular. The concepts of his Cytotoxic T cell study are interwoven with issues in Virus and Priming, CD8, Antigen.
His Virus study incorporates themes from Degranulation and Gene, Homologous recombination. T cell is closely attributed to Vaccinia in his study. His Vaccinia research is multidisciplinary, incorporating elements of Proteome and Computational biology.
His primary areas of study are Antigen, Epitope, Major histocompatibility complex, CD8 and Cell biology. His Antigen study integrates concerns from other disciplines, such as Cell growth, Virology, Immunity and Cytotoxic T cell, Antigen presentation. He has included themes like Naive T cell, Immunogenicity and Antigen-presenting cell in his Virology study.
His Epitope research integrates issues from T cell and MHC class I. David C. Tscharke interconnects Proteome, Plasma protein binding, Vaccinia and Computational biology in the investigation of issues within T cell. His CD8 study combines topics from a wide range of disciplines, such as Inflammation, Tissue homeostasis, Innate lymphoid cell and Lymphocyte.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.
Laura K Mackay;Azad Rahimpour;Joel Z Ma;Nicholas Collins.
Nature Immunology (2013)
A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus.
Magdalini Moutaftsi;Bjoern Peters;Valerie Pasquetto;David C Tscharke.
Nature Biotechnology (2006)
CD8+ T Cell Cross-Priming via Transfer of Proteasome Substrates
Christopher C. Norbury;Christopher C. Norbury;Sameh Basta;Keri B. Donohue;David C. Tscharke.
Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines
David C. Tscharke;David C. Tscharke;Gunasegaran Karupiah;Jie Zhou;Tara Palmore.
Journal of Experimental Medicine (2005)
Anti-CD8 impairs clearance of herpes simplex virus from the nervous system : implications for the fate of virally infected neurons
A Simmons;D C Tscharke.
Journal of Experimental Medicine (1992)
Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses.
Simone L Park;Ali Zaid;Jyh Liang Hor;Susan N Christo.
Nature Immunology (2018)
Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes
Erika Assarsson;Jason A. Greenbaum;Magnus Sundström;Lana Schaffer.
Proceedings of the National Academy of Sciences of the United States of America (2008)
HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation
Carla Oseroff;Ferdynand Kos;Huynh Hoa Bui;Bjoern Peters.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes
David C. Tscharke;David C. Tscharke;Patrick C. Reading;Patrick C. Reading;Geoffrey L. Smith;Geoffrey L. Smith.
Journal of General Virology (2002)
Regulatory T Cells Suppress CD8+ T Cell Responses Induced by Direct Priming and Cross-Priming and Moderate Immunodominance Disparities
S. M. Mansour Haeryfar;Richard J. DiPaolo;David C. Tscharke;Jack R. Bennink.
Journal of Immunology (2005)
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