World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
47
Citations
9324
World Ranking
4503
National Ranking
193

Overview

David C. Tscharke is affiliated with the Australian National University in Australia and focuses their research primarily in the fields of Immunology and Microbiology as well as Medicine. Their scholarly output includes work concentrated on immunology, epidemiology, molecular biology, infectious diseases, and virology.

The scientist's research covers a range of topics including:

  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Herpesvirus Infections and Treatments
  • Poxvirus Research and Outbreaks
  • Virus-based Gene Therapy Research
  • Animal Disease Management and Epidemiology

Several recent papers authored or co-authored by David C. Tscharke illustrate their research interests and contributions. These include:

  • "Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system," 2020, PLoS Computational Biology
  • "Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome," 2020, Nature Communications
  • "Viperin binds STING and enhances the type-I interferon response following dsDNA detection," 2020, Immunology and Cell Biology
  • "Rapid poxvirus engineering using CRISPR/Cas9 as a selection tool," 2020, Communications Biology
  • "Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin," 2021, The Journal of Experimental Medicine

David C. Tscharke frequently collaborates with other researchers. Notable co-authors include:

  • Stewart A. Smith
  • Anthony W. Purcell
  • Carolyn Samer
  • Allison Abendroth
  • Barry Slobedman

Their work is often published in specific academic venues, with multiple publications in:

  • Journal of Virology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunology and Cell Biology
  • Advanced Science
  • The Journal of Infectious Diseases

In addition to journal articles, David C. Tscharke has contributed to book publications, including the title Moral Dimensions of Humour, published in 2024 by Tampere University Press eBooks.

Best Publications

  • The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.

    Laura K Mackay;Azad Rahimpour;Joel Z Ma;Nicholas Collins

  • A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus.

    Magdalini Moutaftsi;Bjoern Peters;Valerie Pasquetto;David C Tscharke

  • Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

    David C. Tscharke;David C. Tscharke;Gunasegaran Karupiah;Jie Zhou;Tara Palmore

  • CD8+ T Cell Cross-Priming via Transfer of Proteasome Substrates

    Christopher C. Norbury;Christopher C. Norbury;Sameh Basta;Keri B. Donohue;David C. Tscharke

  • Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses.

    Simone L Park;Ali Zaid;Jyh Liang Hor;Susan N Christo

  • Anti-CD8 impairs clearance of herpes simplex virus from the nervous system : implications for the fate of virally infected neurons

    A Simmons;D C Tscharke

  • Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

    Erika Assarsson;Jason A. Greenbaum;Magnus Sundström;Lana Schaffer

  • Tissue-resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance.

    Thomas Gebhardt;Umaimainthan Palendira;David C Tscharke;Sammy Bedoui

  • Kinetics of antigen expression and epitope presentation during virus infection.

    Nathan Paul Croft;Stewart A Smith;Yik Chun Wong;Chor Teck Tan

  • HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

    Carla Oseroff;Ferdynand Kos;Huynh Hoa Bui;Bjoern Peters

  • Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes

    David C. Tscharke;David C. Tscharke;Patrick C. Reading;Patrick C. Reading;Geoffrey L. Smith;Geoffrey L. Smith

  • Sizing up the key determinants of the CD8 + T cell response

    David C Tscharke;Nathan P Croft;Peter C Doherty;Peter C Doherty;Nicole L La Gruta

  • The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence.

    Nathan Bartlett;Nathan Bartlett;Julian A. Symons;David C. Tscharke;David C. Tscharke;Geoffrey L. Smith;Geoffrey L. Smith

  • Regulatory T Cells Suppress CD8+ T Cell Responses Induced by Direct Priming and Cross-Priming and Moderate Immunodominance Disparities

    S. M. Mansour Haeryfar;Richard J. DiPaolo;David C. Tscharke;Jack R. Bennink

  • Poxvirus CD8+ T-Cell Determinants and Cross-Reactivity in BALB/c Mice

    David C. Tscharke;David C. Tscharke;Wai-Ping Woo;Isaac G. Sakala;John Sidney

  • A study of the vaccinia virus interferon-γ receptor and its contribution to virus virulence

    Julian A. Symons;David C. Tscharke;Nicola Price;Geoffrey L. Smith

  • A model for vaccinia virus pathogenesis and immunity based on intradermal injection of mouse ear pinnae.

    David C. Tscharke;Geoffrey L. Smith

  • Chronic Ethanol Ingestion in Rats Decreases Granulocyte-Macrophage Colony-Stimulating Factor Receptor Expression and Downstream Signaling in the Alveolar Macrophage

    Pratibha C. Joshi;Lisa Applewhite;Jeffrey D. Ritzenthaler;Jesse Roman

  • Most viral peptides displayed by class I MHC on infected cells are immunogenic.

    Nathan P Croft;A. J. Stewart Smith;Jana Pickering;John Sidney

  • Dual-specific chimeric antigen receptor T cells and an indirect vaccine eradicate a variety of large solid tumors in an immunocompetent, self-antigen setting.

    Clare Y. Slaney;Clare Y. Slaney;Bianca von Scheidt;Bianca von Scheidt;Alexander J Davenport;Alexander J Davenport;Paul A. Beavis;Paul A. Beavis

  • The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model.

    Julian A. Symons;Elizabeth Adams;David C. Tscharke;Patrick C. Reading

  • Immunodominance of Poxviral-Specific CTL in a Human Trial of Recombinant-Modified Vaccinia Ankara

    Caroline L. Smith;Fareed Mirza;Valerie Pasquetto;David C. Tscharke

Frequent Co-Authors

Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Geoffrey L. Smith
Geoffrey L. Smith University of Oxford
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology
Anthony W. Purcell
Anthony W. Purcell Monash University
Jonathan W. Yewdell
Jonathan W. Yewdell National Institute of Allergy and Infectious Diseases
John Sidney
John Sidney La Jolla Institute For Allergy & Immunology
Jack R. Bennink
Jack R. Bennink National Institute of Allergy and Infectious Diseases
Howard M. Grey
Howard M. Grey La Jolla Institute For Allergy & Immunology
Nicole L. La Gruta
Nicole L. La Gruta Monash University
Carla Oseroff
Carla Oseroff La Jolla Institute For Allergy & Immunology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in expanding their expertise beyond Immunology, various healthcare-related online degrees offer promising career paths. Nursing professionals, for example, can explore programs tailored to their needs. The easiest fnp program options can provide a smoother transition into becoming a Family Nurse Practitioner, balancing rigorous coursework with manageable demands.

Psychiatric nursing is another growing field. Students aiming to specialize can find the best pmhnp programs online which ensure strong clinical placement rates, essential for hands-on experience and job readiness. For budget-conscious learners, programs labeled as the cheapest psych np programs online offer quality education without overwhelming expenses.

Understanding financial outcomes is crucial when making educational choices. Exploring data on how much does a dnp make illuminates potential earnings for Doctor of Nursing Practice graduates, assisting prospective students in evaluating return on investment and aligning their career goals accordingly.

Best Scientists Citing David C. Tscharke

Trending Scientists

Recently Published Articles