D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 40 Citations 7,260 111 World Ranking 3971 National Ranking 179

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Virus

His main research concerns Virology, Virus, Vaccinia, Antigen and Poxviridae. His work deals with themes such as Immunodominance and Immunogenicity, which intersect with Virology. David C. Tscharke usually deals with Virus and limits it to topics linked to Gene and Cell culture and Glycoprotein.

His research integrates issues of Herpes simplex virus and Cell biology in his study of Antigen. His Poxviridae research also works with subjects such as

  • Orthopoxvirus that connect with fields like Monkeypox virus, Monkeypox and Gene expression,
  • Ectromelia virus, which have a strong connection to Smallpox vaccine, Cowpox virus and Cowpox. His biological study spans a wide range of topics, including Cytotoxic T cell, Molecular biology and T cell.

His most cited work include:

  • The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin. (651 citations)
  • A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus. (407 citations)
  • Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines (279 citations)

What are the main themes of his work throughout his whole career to date?

David C. Tscharke mainly investigates Virology, Vaccinia, Virus, Cytotoxic T cell and Immunology. David C. Tscharke has researched Virology in several fields, including Immunodominance, T cell, Antigen, Immunogenicity and Epitope. The Immunodominance study combines topics in areas such as Virus antigen and Modified vaccinia Ankara.

His Vaccinia study improves the overall literature in Genetics. The various areas that David C. Tscharke examines in his Virus study include Molecular biology and Gene, Mutant, Virulence. His Cytotoxic T cell research includes elements of Priming, CD8 and T-cell receptor.

He most often published in these fields:

  • Virology (81.45%)
  • Vaccinia (59.68%)
  • Virus (58.06%)

What were the highlights of his more recent work (between 2017-2021)?

  • Virology (81.45%)
  • Cytotoxic T cell (35.48%)
  • Epitope (26.61%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Virology, Cytotoxic T cell, Epitope, T cell and Immune system. David C. Tscharke studies Virology, focusing on Herpes simplex virus in particular. The concepts of his Cytotoxic T cell study are interwoven with issues in Virus and Priming, CD8, Antigen.

His Virus study incorporates themes from Degranulation and Gene, Homologous recombination. T cell is closely attributed to Vaccinia in his study. His Vaccinia research is multidisciplinary, incorporating elements of Proteome and Computational biology.

Between 2017 and 2021, his most popular works were:

  • Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses. (159 citations)
  • Tissue-resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance. (80 citations)
  • Most viral peptides displayed by class I MHC on infected cells are immunogenic. (49 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Virus

His primary areas of study are Antigen, Epitope, Major histocompatibility complex, CD8 and Cell biology. His Antigen study integrates concerns from other disciplines, such as Cell growth, Virology, Immunity and Cytotoxic T cell, Antigen presentation. He has included themes like Naive T cell, Immunogenicity and Antigen-presenting cell in his Virology study.

His Epitope research integrates issues from T cell and MHC class I. David C. Tscharke interconnects Proteome, Plasma protein binding, Vaccinia and Computational biology in the investigation of issues within T cell. His CD8 study combines topics from a wide range of disciplines, such as Inflammation, Tissue homeostasis, Innate lymphoid cell and Lymphocyte.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.

Laura K Mackay;Azad Rahimpour;Joel Z Ma;Nicholas Collins.
Nature Immunology (2013)

1017 Citations

A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus.

Magdalini Moutaftsi;Bjoern Peters;Valerie Pasquetto;David C Tscharke.
Nature Biotechnology (2006)

547 Citations

CD8+ T Cell Cross-Priming via Transfer of Proteasome Substrates

Christopher C. Norbury;Christopher C. Norbury;Sameh Basta;Keri B. Donohue;David C. Tscharke.
Science (2004)

361 Citations

Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

David C. Tscharke;David C. Tscharke;Gunasegaran Karupiah;Jie Zhou;Tara Palmore.
Journal of Experimental Medicine (2005)

358 Citations

Anti-CD8 impairs clearance of herpes simplex virus from the nervous system : implications for the fate of virally infected neurons

A Simmons;D C Tscharke.
Journal of Experimental Medicine (1992)

296 Citations

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses.

Simone L Park;Ali Zaid;Jyh Liang Hor;Susan N Christo.
Nature Immunology (2018)

251 Citations

Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

Erika Assarsson;Jason A. Greenbaum;Magnus Sundström;Lana Schaffer.
Proceedings of the National Academy of Sciences of the United States of America (2008)

193 Citations

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

Carla Oseroff;Ferdynand Kos;Huynh Hoa Bui;Bjoern Peters.
Proceedings of the National Academy of Sciences of the United States of America (2005)

168 Citations

Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes

David C. Tscharke;David C. Tscharke;Patrick C. Reading;Patrick C. Reading;Geoffrey L. Smith;Geoffrey L. Smith.
Journal of General Virology (2002)

167 Citations

Regulatory T Cells Suppress CD8+ T Cell Responses Induced by Direct Priming and Cross-Priming and Moderate Immunodominance Disparities

S. M. Mansour Haeryfar;Richard J. DiPaolo;David C. Tscharke;Jack R. Bennink.
Journal of Immunology (2005)

159 Citations

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