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Immunology

D-Index
79
Citations
29354
World Ranking
1664
National Ranking
46

Overview

Jacques Fellay is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research spans multiple fields centered on medicine, biochemistry, genetics, molecular biology, immunology, and microbiology, with particular attention to infectious diseases, immunology, epidemiology, molecular biology, and genetics.

The scientist has contributed extensively to topics related to HIV research and treatment, HIV/AIDS research and interventions, and HIV-related health complications and treatments. Additional areas of focus include immune cell function and interaction, HIV/AIDS drug development and treatment, respiratory viral infections research, and genetic associations and epidemiology.

Fellay's recent scholarly output highlights a variety of studies concerning infectious diseases and immune responses, particularly in the context of COVID-19. Noteworthy publications include:

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 (2020, Science)
  • COVID-19 epidemic in Switzerland: on the importance of testing, contact tracing and isolation (2020, Swiss Medical Weekly)
  • Human genetic and immunological determinants of critical COVID-19 pneumonia (2022, Nature)
  • A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection (2020, Cell)
  • Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption (2021, Nature Communications)

Frequent collaborators in their research include Huldrych F. Günthard, Enos Bernasconi, Roger D. Kouyos, Matthias Cavassini, and Alexandra Calmy. These co-authors have worked with Fellay on numerous studies, reflecting longstanding research partnerships.

Their work has been published repeatedly in several scholarly venues, with a significant presence in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Infectious Diseases
  • The Journal of Infectious Diseases
  • Zenodo (CERN European Organization for Nuclear Research)
  • The Journal of Experimental Medicine

Jacques Fellay's research contributions align with ongoing efforts to understand infectious diseases and immune mechanisms at genetic and molecular levels, underlining intersections between pathogen biology and host immune responses. Their studies often address critical public health questions pertaining to viral infections, immunity, and epidemiological strategies.

Best Publications

  • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.

    Dongliang Ge;Jacques Fellay;Alexander J. Thompson;Jason S. Simon

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1

    Jacques Fellay;Kevin V. Shianna;Dongliang Ge;Sara Colombo

  • Interleukin-28B Polymorphism Improves Viral Kinetics and Is the Strongest Pretreatment Predictor of Sustained Virologic Response in Genotype 1 Hepatitis C Virus

    Alexander J. Thompson;Andrew J. Muir;Andrew J. Muir;Mark S. Sulkowski;Dongliang Ge

  • Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study.

    Jacques Fellay;Catia Marzolini;Emma R. Meaden;David J. Back

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Human genetic and immunological determinants of critical COVID-19 pneumonia

    Unknown

  • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.

    Jacques Fellay;Alexander J. Thompson;Dongliang Ge;Curtis E. Gumbs

  • A global scientific strategy to cure hepatitis B

    Peter A Revill;Francis V Chisari;Joan M Block;Maura Dandri

  • Common genetic variation and the control of HIV-1 in humans.

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

  • Prevalence of adverse events associated with potent antiretroviral treatment: Swiss HIV Cohort Study

    Jacques Fellay;Bruno Ledergerber;Enos Bernasconi;Hansjakob Furrer

  • IL28B genotype is associated with differential expression of intrahepatic interferon‐stimulated genes in patients with chronic hepatitis C

    Thomas J. Urban;Alexander J. Thompson;Shelton S. Bradrick;Jacques Fellay

  • Influence of HLA-C Expression Level on HIV Control

    Richard Apps;Richard Apps;Ying Qi;Ying Qi;Jonathan M. Carlson;Haoyan Chen;Haoyan Chen

  • Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection

    Chantal Csajka;Catia Marzolini;Karin Fattinger;Laurent A. Décosterd

  • HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

    Rasmi Thomas;Richard Apps;Ying Qi;Xiaojiang Gao

  • Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

    Etienne Patin;Milena Hasan;Jacob Bergstedt;Vincent Rouilly

  • A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

    Jean-Laurent Casanova;Helen C. Su;Covid Human Genetic Effort

  • Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

    Barbara Piasecka;Darragh Duffy;Alejandra Urrutia;Alejandra Urrutia;Helene Quach

  • Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia and Decrease the Need for Ribavirin Dose Reduction

    Alexander J. Thompson;Jacques Fellay;Keyur Patel;Keyur Patel;Hans L. Tillmann;Hans L. Tillmann

  • Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

    Margalida Rotger;Judith Dalmau;Andri Rauch;Paul McLaren

  • Evidence of dysregulation of dendritic cells in primary HIV infection.

    Rachel Lubong Sabado;Rachel Lubong Sabado;Meagan O'Brien;Meagan O'Brien;Abhignya Subedi;Abhignya Subedi;Li Qin;Li Qin

  • Common Genetic Variation and the Control of HIV-1 in Humans

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

Frequent Co-Authors

Amalio Telenti
Amalio Telenti VIR Biotechnology (United States)
David Goldstein
David Goldstein University of New South Wales
Huldrych F. Günthard
Huldrych F. Günthard University of Zurich
Enos Bernasconi
Enos Bernasconi Universita della Svizzera Italiana
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Kevin V. Shianna
Kevin V. Shianna Duke University
Andri Rauch
Andri Rauch University of Bern
Matthias Cavassini
Matthias Cavassini University of Lausanne
Manuel Battegay
Manuel Battegay University Hospital of Basel
Dongliang Ge
Dongliang Ge Apostle Diagnostics

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Related Online Degrees & Career Pathways

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