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Kevin V. Shianna

Kevin V. Shianna

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
26034
World Ranking
12253
National Ranking
5238

Overview

Kevin V. Shianna is affiliated with Duke University in the United States and has contributed extensively to the field of medicine, with a particular focus on epidemiology, virology, pharmacology, psychiatry and mental health, and hepatology.

They have published research in venues primarily associated with UNC Libraries, where they have a total of seven publications. Their multidisciplinary work spans several main topics, including:

  • HIV Research and Treatment
  • Hepatitis C virus research
  • Influenza Virus Research Studies
  • Hepatitis B Virus Studies
  • Blood groups and transfusion
  • Hemoglobinopathies and Related Disorders
  • Biochemical and Molecular Research

Kevin V. Shianna has co-authored multiple papers with several frequent collaborators. These include David B. Goldstein, John G. McHutchison, Alexander Thompson, Nezam H. Afdhal, and Michael Fried.

Selected recent publications reflect their research activity in 2020 and include the following:

  • Quantitation of Pretreatment Serum IP-10 Improves the Predictive Value of an IL28B Gene Polymorphism for Hepatitis C Treatment Response (2020), UNC Libraries
  • Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia and Decrease the Need for Ribavirin Dose Reduction (2020), UNC Libraries
  • Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population (2020), UNC Libraries
  • Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs (2020), UNC Libraries
  • Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1 (2020), UNC Libraries

Throughout their career, Kevin V. Shianna has focused on genetic and molecular factors related to infectious diseases, including virus susceptibility and treatment response. Their publications address connections between gene polymorphisms and clinical outcomes in viral infections such as Hepatitis C and HIV.

Their portfolio of work includes epidemiological and pharmacological approaches that contribute to understanding disease mechanisms and treatment effects. This work intersects with mental health and liver-related illnesses, reflecting diverse interests within medical research.

Best Publications

  • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.

    Dongliang Ge;Jacques Fellay;Alexander J. Thompson;Jason S. Simon

  • Large recurrent microdeletions associated with schizophrenia

    Hreinn Stefansson;Dan Rujescu;Sven Cichon;Olli P. H. Pietilainen

  • A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1

    Jacques Fellay;Kevin V. Shianna;Dongliang Ge;Sara Colombo

  • HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans

    Mark McCormack;Ana Alfirevic;Stephane Bourgeois;John J. Farrell

  • Interleukin-28B Polymorphism Improves Viral Kinetics and Is the Strongest Pretreatment Predictor of Sustained Virologic Response in Genotype 1 Hepatitis C Virus

    Alexander J. Thompson;Andrew J. Muir;Andrew J. Muir;Mark S. Sulkowski;Dongliang Ge

  • Natural selection on EPAS1 (HIF2α) associated with low hemoglobin concentration in Tibetan highlanders

    Cynthia M. Beall;Gianpiero L. Cavalleri;Libin Deng;Robert C. Elston

  • A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

    Sreekumar G. Pillai;Dongliang Ge;Guohua Zhu;Xiangyang Kong

  • A genome-wide investigation of SNPs and CNVs in schizophrenia

    Anna C. Need;Dongliang Ge;Michael E. Weale;Jessica Maia

  • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.

    Jacques Fellay;Alexander J. Thompson;Dongliang Ge;Curtis E. Gumbs

  • Clinical application of exome sequencing in undiagnosed genetic conditions

    Anna C Need;Vandana Shashi;Yuki Hitomi;Kelly Schoch

  • Long-Range LD Can Confound Genome Scans in Admixed Populations

    Alkes L. Price;Alkes L. Price;Michael E. Weale;Nick Patterson;Simon R. Myers;Simon R. Myers

  • Common genetic variation and the control of HIV-1 in humans.

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

  • IL28B genotype is associated with differential expression of intrahepatic interferon‐stimulated genes in patients with chronic hepatitis C

    Thomas J. Urban;Alexander J. Thompson;Shelton S. Bradrick;Jacques Fellay

  • De novo mutations in ATP1A3 cause alternating hemiplegia of childhood

    Erin L Heinzen;Kathryn J Swoboda;Yuki Hitomi;Fiorella Gurrieri

  • Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.

    Michael J. Ombrello;Elaine F. Remmers;Guangping Sun;Alexandra F. Freeman

  • A Polymorphism Near IL28B Is Associated With Spontaneous Clearance of Acute Hepatitis C Virus and Jaundice

    Hans L. Tillmann;Alex J. Thompson;Keyur Patel;Manfred Wiese

  • An IL28B Polymorphism Determines Treatment Response of Hepatitis C Virus Genotype 2 or 3 Patients Who Do Not Achieve a Rapid Virologic Response

    Alessandra Mangia;Alexander J. Thompson;Rosanna Santoro;Valeria Piazzolla

  • Tissue-Specific Genetic Control of Splicing: Implications for the Study of Complex Traits

    Erin L Heinzen;Dongliang Ge;Kenneth D Cronin;Jessica M Maia

  • Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes.

    Erin L. Heinzen;Rodney A. Radtke;Thomas J. Urban;Gianpiero L. Cavalleri

  • Common Genetic Variation and the Control of HIV-1 in Humans

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

Frequent Co-Authors

David Goldstein
David Goldstein University of New South Wales
Dongliang Ge
Dongliang Ge Apostle Diagnostics
Jacques Fellay
Jacques Fellay École Polytechnique Fédérale de Lausanne
Alexander J. Thompson
Alexander J. Thompson Ascension Health
John G. McHutchison
John G. McHutchison Duke University
Erin L. Heinzen
Erin L. Heinzen University of North Carolina at Chapel Hill
Nezam H. Afdhal
Nezam H. Afdhal Beth Israel Deaconess Medical Center
Hans L. Tillmann
Hans L. Tillmann East Carolina University
Andrew J. Muir
Andrew J. Muir Duke University
Elizabeth T. Cirulli
Elizabeth T. Cirulli Duke University

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