World's Best Scientists 2026 revealed!
José Manuel Fernández-Real

José Manuel Fernández-Real

Award Badge
Medicine
Spain
2023

D-Index & Metrics

Medicine

D-Index
108
Citations
44545
World Ranking
5988
National Ranking
83

Research.com Recognitions

  • 2023 - Research.com Medicine in Spain Leader Award

Overview

José Manuel Fernández-Real is affiliated with the University of Girona in Spain and has a significant body of research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Physiology, Molecular Biology, Epidemiology, Endocrinology, Diabetes and Metabolism, and Biological Psychiatry.

The scientist has authored numerous papers on topics related to gut microbiota, metabolism, and related disorders. Key areas of research include gut microbiota and health, adipose tissue and metabolism, diet and metabolism studies, adipokines and inflammation in metabolic diseases, tryptophan and brain disorders, liver disease diagnosis and treatment, and iron metabolism and disorders.

Among recent publications are:

  • Definition and diagnostic criteria of clinical obesity, 2025, The Lancet Diabetes & Endocrinology
  • Microbiota alterations in proline metabolism impact depression, 2022, Cell Metabolism
  • Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids, 2020, Cell Metabolism
  • Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome, 2021, Microbiome
  • Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status, 2020, Microbiome

Frequent collaborators in their research include José María Moreno-Navarrete, Jordi Mayneris-Perxachs, María Arnoriaga-Rodríguez, Josep Puig, and Jèssica Latorre, indicating a strong network of co-authorship over numerous studies.

Publication venues where this scientist frequently appears include:

  • International Journal of Obesity
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gut
  • Molecular Nutrition & Food Research
  • Microbiome

Their research contributions provide insight into the interaction between metabolic pathways, gut microbiota, and their effects on systemic conditions such as obesity, liver disease, and brain disorders. The scientist's investigations cover biochemical and physiological aspects with an emphasis on the role of inflammation, nutrient metabolism, and microbiome-related mechanisms.

Best Publications

  • Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

    Hao Wu;Eduardo Esteve;Eduardo Esteve;Valentina Tremaroli;Muhammad Tanweer Khan

  • Insulin resistance and chronic cardiovascular inflammatory syndrome.

    José Manuel Fernández-Real;Wifredo Ricart

  • Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance

    José María Moreno-Navarrete;Francisco Ortega;Marta Serrano;Ester Guerra

  • Cross-talk between iron metabolism and diabetes.

    José Manuel Fernández-Real;Abel López-Bermejo;Wifredo Ricart

  • Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women.

    José-Manuel Fernandez-Real;Montserrat Vayreda;Cristobal Richart;Cristina Gutierrez

  • Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaén and Córdoba (Spain) 2008.

    J. López-Miranda;F. Pérez-Jiménez;E. Ros;R. De Caterina

  • Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

    Lesley Hoyles;José-Manuel Fernández-Real;Massimo Federici;Matteo Serino;Matteo Serino

  • Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: implications for insulin resistance.

    Husam Ghanim;Sanaa Abuaysheh;Ching Ling Sia;Kelly Korzeniewski

  • Physiology and role of irisin in glucose homeostasis

    Nikolaos Perakakis;Georgios A. Triantafyllou;José Manuel Fernández-Real;Joo Young Huh

  • Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

    Sébastien Jacquemont;Alexandre Reymond;Flore Zufferey;Louise Harewood

  • Dyslipidemia and inflammation: an evolutionary conserved mechanism

    Eduardo Esteve;Wifredo Ricart;José Manuel Fernández-Real

  • Targeting the Circulating MicroRNA Signature of Obesity

    Francisco José Ortega;Josep María Mercader;Victoria Catalán;Victoria Catalán;José María Moreno-Navarrete

  • Blood Letting in High-Ferritin Type 2 Diabetes: Effects on Insulin Sensitivity and β-Cell Function

    José Manuel Fernández-Real;Georgina Peñarroja;Antoni Castro;Fernando García-Bragado

  • Serum Ferritin as a Component of the Insulin Resistance Syndrome

    José-Manuel Fernández-Real;Wifredo Ricart-Engel;Enric Arroyo;Rafael Balançá

  • MiRNA expression profile of human subcutaneous adipose and during adipocyte differentiation.

    Francisco J. Ortega;José M. Moreno-Navarrete;Gerard Pardo;Monica Sabater

  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

    Tuomas O Kilpeläinen;M Carola Zillikens;Alena Stančákova;Francis M Finucane

  • Profiling of Circulating MicroRNAs Reveals Common MicroRNAs Linked to Type 2 Diabetes That Change With Insulin Sensitization

    Francisco J Ortega;Josep M Mercader;José María Moreno-Navarrete;Oscar Rovira

  • Innate immunity, insulin resistance and type 2 diabetes.

    J. M. Fernández-Real;J. C. Pickup

  • Circulating omentin concentration increases after weight loss

    José María Moreno-Navarrete;Victoria Catalán;Francisco A Ortega;Javier Gómez-Ambrosi

  • Interleukin-6 gene polymorphism and lipid abnormalities in healthy subjects.

    José-Manuel Fernández-Real;Montserrat Broch;Joan Vendrell Cristóbal Richart;Wifredo Ricart

Frequent Co-Authors

Wifredo Ricart
Wifredo Ricart Instituto de Salud Carlos III
Gema Frühbeck
Gema Frühbeck University of Navarra
Francisco J. Tinahones
Francisco J. Tinahones University of Malaga
Fernando Fernández-Aranda
Fernando Fernández-Aranda University of Barcelona
Susana Jiménez-Murcia
Susana Jiménez-Murcia University of Barcelona
Javier Gómez-Ambrosi
Javier Gómez-Ambrosi University of Navarra
Roser Granero
Roser Granero Autonomous University of Barcelona
Rafael de la Torre
Rafael de la Torre Pompeu Fabra University
Rosa M. Baños
Rosa M. Baños University of Valencia
Felipe F. Casanueva
Felipe F. Casanueva University of Santiago de Compostela

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