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Biology and Biochemistry

D-Index
60
Citations
14484
World Ranking
11860
National Ranking
216

Overview

Mathieu Vinken is affiliated with the Vrije Universiteit Brussel in Belgium and has a significant body of research primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their scholarly contributions span a range of topics and subfields, highlighting a focus on molecular and pharmacological aspects of liver and toxicology sciences.

Their research often appears in established scientific venues. Frequent publication outlets include Toxicology Letters, with 24 publications; Archives of Toxicology, totaling 15 papers; ALTEX, with 12 publications; International Journal of Molecular Sciences, featuring 9 papers; and Toxicology, also with 9 publications.

Vinken's main fields of study are Medicine and Biochemistry, Genetics, and Molecular Biology, with notable subfields such as Molecular Biology, Pharmacology, Epidemiology, Computational Theory and Mathematics, and Hepatology. This scientific focus is reflected in the main topics of their work:

  • Connexins and lens biology
  • Computational Drug Discovery Methods
  • Drug-Induced Hepatotoxicity and Protection
  • Liver Disease Diagnosis and Treatment
  • Animal testing and alternatives
  • Drug Transport and Resistance Mechanisms
  • Liver physiology and pathology

Mathieu Vinken has coauthored extensively with several researchers including Julen Sanz-Serrano, Raf Van Campenhout, Bruno Cogliati, Lindsey Devisscher, and M Cronin, reflecting collaborative work in toxicology and molecular biology.

Selected recent publications exemplify the range and focus of their work:

  • "New approach methodologies in human regulatory toxicology - Not if, but how and when!", 2023, published in Environment International
  • "Mitochondria as the Target of Hepatotoxicity and Drug-Induced Liver Injury: Molecular Mechanisms and Detection Methods", 2022, published in International Journal of Molecular Sciences
  • "Safer chemicals using less animals: kick-off of the European ONTOX project", 2021, published in Toxicology
  • "Mechanisms Underlying Connexin Hemichannel Activation in Disease", 2021, published in International Journal of Molecular Sciences
  • "Rodent models of cholestatic liver disease: A practical guide for translational research", 2021, published in Liver International

Best Publications

  • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

    Patricio Godoy;Nicola J. Hewitt;Ute Albrecht;Melvin E. Andersen

  • Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

    Sarah Adler;David Basketter;Stuart Creton;Olavi Pelkonen

  • The adverse outcome pathway concept: A pragmatic tool in toxicology

    Mathieu Vinken

  • Adverse outcome pathways: opportunities, limitations and open questions.

    Marcel Leist;Ahmed Ghallab;Ahmed Ghallab;Rabea Graepel;Rosemarie Marchan

  • Molecular Mechanisms Underlying the Dedifferentiation Process of Isolated Hepatocytes and Their Cultures

    Greetje Elaut;Tom Henkens;Peggy Papeleu;Sarah Snykers

  • Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction.

    Danny Bavli;Sebastian Prill;Elishai Ezra;Gahl Levy

  • Experimental models of liver fibrosis

    Sara Crespo Yanguas;Bruno Cogliati;Joost Willebrords;Michaël Maes

  • Connexins and their channels in cell growth and cell death

    Mathieu Vinken;Tamara Vanhaecke;Peggy Papeleu;Sarah Snykers

  • Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.

    Nan Wang;Elke De Vuyst;Raf Ponsaerts;Kerstin Boengler

  • Connexin-related signaling in cell death: to live or let die?

    E Decrock;M Vinken;E De Vuyst;D V Krysko

  • Ca2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells

    Elke De Vuyst;Nan Wang;Elke Decrock;Marijke De Bock

  • Experimental models of hepatotoxicity related to acute liver failure

    Michaël Maes;Mathieu Vinken;Hartmut Jaeschke

  • Paracrine signaling through plasma membrane hemichannels.

    Nan Wang;Marijke De Bock;Elke Decrock;Mélissa Bol

  • Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model.

    E. Decrock;E. De Vuyst;M. Vinken;M. Van Moorhem

  • Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research

    Joost Willebrords;Isabel Veloso Alves Pereira;Michaël Maes;Sara Crespo Yanguas

  • Connexin Channels Provide a Target to Manipulate Brain Endothelial Calcium Dynamics and Blood—Brain Barrier Permeability

    Marijke De Bock;Maxime Culot;Nan Wang;Mélissa Bol

  • Isolation of rat hepatocytes.

    Peggy Papeleu;Tamara Vanhaecke;Tom Henkens;Greetje Elaut

  • Inhibitors of connexin and pannexin channels as potential therapeutics.

    Joost Willebrords;Michaël Maes;Sara Crespo Yanguas;Mathieu Vinken

  • Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies

    J. Fraczek;J. Bolleyn;T. Vanhaecke;V. Rogiers

  • Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum.

    Catheleyne D'hondt;Raf Ponsaerts;Humbert De Smedt;Mathieu Vinken

Frequent Co-Authors

Vera Rogiers
Vera Rogiers Vrije Universiteit Brussel
Luc Leybaert
Luc Leybaert Ghent University
Hartmut Jaeschke
Hartmut Jaeschke University of Kansas
Jos C. S. Kleinjans
Jos C. S. Kleinjans Maastricht University
Jan G. Hengstler
Jan G. Hengstler TU Dortmund University
Agapios Sachinidis
Agapios Sachinidis University of Cologne
Hector C. Keun
Hector C. Keun Imperial College London
Albert Sickmann
Albert Sickmann Leibniz Institute for Neurobiology
Joost H.M. van Delft
Joost H.M. van Delft Maastricht University

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