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Biology and Biochemistry

D-Index
66
Citations
12183
World Ranking
8873
National Ranking
308

Overview

Arun Seth is affiliated with the Sunnybrook Health Science Centre in Canada and has contributed extensively in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans primarily Molecular Biology, Radiology, Nuclear Medicine and Imaging, Pulmonary and Respiratory Medicine, Cancer Research, and Epidemiology.

The main research topics covered by Arun Seth include:

  • Radiomics and Machine Learning in Medical Imaging
  • MRI in cancer diagnosis
  • Endometrial and Cervical Cancer Treatments
  • Metastasis and carcinoma case studies
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Autophagy in Disease and Therapy

Recent papers authored or co-authored by Arun Seth highlight a focus on cancer and molecular biology, including:

  • MR-guided focused ultrasound liquid biopsy enriches circulating biomarkers in patients with brain tumors, 2021, Neuro-Oncology
  • Differentiated exophytic vulvar intraepithelial lesion: Clinicopathologic and molecular analysis documenting its relationship with verrucous carcinoma of the vulva, 2020, Modern Pathology
  • Mesonephric-like adenocarcinoma of the female genital tract: novel observations and detailed molecular characterisation of mixed tumours and mesonephric-like carcinosarcomas, 2023, Histopathology
  • CTNNB1 Mutations and Aberrant β-Catenin Expression in Ovarian Endometrioid Carcinoma, 2020, The American Journal of Surgical Pathology
  • MiR-139 Induces an Interferon-β Response in Prostate Cancer Cells by Binding to RIG-1, 2021, Cancer Genomics & Proteomics

Frequent co-authors collaborating with Arun Seth include:

  • Yutaka Amemiya
  • Jelena Mirković
  • Carlos Parra-Herran
  • Robert K. Nam
  • Ekaterina Olkhov-Mitsel

Arun Seth has published repeatedly in journals such as:

  • Cancer Research
  • Modern Pathology
  • Histopathology
  • Cancer Genomics & Proteomics
  • Alzheimer's & Dementia

The scope of Arun Seth's work reflects multidisciplinary integration with emphases on medical imaging techniques, cancer diagnostics, and molecular mechanisms. The research outputs demonstrate involvement in both clinical pathology and molecular oncology, contributing to the understanding of cancer progression and biomarker development.

Best Publications

  • Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy.

    Robert K. Nam;Robert K. Nam;Refik Saskin;Yuna Lee;Ying Liu

  • ETS transcription factors and their emerging roles in human cancer.

    Arun Seth;Arun Seth;Dennis K. Watson

  • Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts

    Jiaxu Wang;Honghong Chen;Arun Seth;Christopher A. McCulloch

  • Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer.

    Nam Rk;Sugar L;Yang W;Srivastava S

  • The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation

    Ismail Kola;Sarah Brookes;Anthony R. Green;Richard Garber

  • The ubiquitin-mediated protein degradation pathway in cancer: therapeutic implications.

    Angelika M. Burger;Arun K. Seth;Arun K. Seth

  • Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice.

    Sony Heru Sumarsono;Trevor J. Wilson;Martin J. Tymms;Deon J. Venter

  • Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases

    M Gonzatti-Haces;A Seth;M Park;T Copeland

  • Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression.

    Robert K Nam;Linda Sugar;Zhenghui Wang;Wenyi Yang

  • ETS1, NFkappaB and AP1 synergistically transactivate the human GM-CSF promoter.

    Ross S Thomas;Martin J Tymms;Leigh H McKinlay;M F Shannon

  • From Melanocyte to Metastatic Malignant Melanoma

    Bizhan Bandarchi;Linglei Ma;Roya Navab;Arun Seth

  • Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors

    Jukka Westermarck;Arun Seth;Veli-Matti Kähäri

  • Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer.

    Angelika M. Burger;Brian Leyland-Jones;Kris Banerjee;Demetri D. Spyropoulos

  • Ets transcription factors and targets in osteogenesis

    Afshin Raouf;Arun Seth;Arun Seth

  • IGFBP7 Binds to the IGF-1 Receptor and Blocks Its Activation by Insulin-Like Growth Factors

    Valentina Evdokimova;Cristina E. Tognon;Tania Benatar;Wenyi Yang

  • A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer.

    Martin J Tymms;Annie Yn Ng;Ross S Thomas;Brian C Schutte

  • Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors.

    Christopher M Overall;Eric M Tam;Reinhild Kappelhoff;Andrea Connor

  • FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements.

    Dennis K Watson;Lois Robinson;David R Hodge;Ismail Kola

  • Global transcriptome analysis of formalin-fixed prostate cancer specimens identifies biomarkers of disease recurrence.

    Qi Long;Jianpeng Xu;Adeboye O. Osunkoya;Soma Sannigrahi

  • A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement in human carcinoma cell lines.

    Jiong Zhou;Annie Yn Ng;Martin J Tymms;Lars S Jermiin

Frequent Co-Authors

Takis S. Papas
Takis S. Papas National Institutes of Health
Carlos S. Moreno
Carlos S. Moreno Emory University
Steven A. Narod
Steven A. Narod University of Toronto
Burton B. Yang
Burton B. Yang University of Toronto
Laurence Klotz
Laurence Klotz University of Toronto
Dennis K. Watson
Dennis K. Watson Medical University of South Carolina
Calvin P.H. Vary
Calvin P.H. Vary Maine Medical Center
Christopher A. McCulloch
Christopher A. McCulloch University of Toronto
Ismail Kola
Ismail Kola MSD (United States)
Yaou Zhang
Yaou Zhang Tsinghua University

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