World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Molecular Biology
USA
2026

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Best Scientists

D-Index
185
Citations
157991
World Ranking
504
National Ranking
327

Molecular Biology

D-Index
188
Citations
161525
World Ranking
28
National Ranking
19

Medicine

D-Index
192
Citations
169037
World Ranking
242
National Ranking
162

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2020 - Member of the National Academy of Sciences
  • 2014 - Fellow of the American Academy of Arts and Sciences
  • 2014 - Fellow, National Academy of Inventors
  • 2009 - Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center
  • 2009 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Arul M. Chinnaiyan is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions to Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Oncology, and Surgery.

The scientist's main areas of study include Prostate Cancer Treatment and Research, Epigenetics and DNA Methylation, Prostate Cancer Diagnosis and Treatment, Cancer Genomics and Diagnostics, Ubiquitin and proteasome pathways, Cancer-related gene regulation, and Cancer, Hypoxia, and Metabolism.

Key recent publications include:

  • Cancer SLC43A2 alters T cell methionine metabolism and histone methylation (2020, Nature)
  • The DNA methylation landscape of advanced prostate cancer (2020, Nature Genetics)
  • Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes (2021, Nature Communications)
  • CDK12-Mutated Prostate Cancer: Clinical Outcomes With Standard Therapies and Immune Checkpoint Blockade (2020, JCO Precision Oncology)
  • Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin (2023, Cancer Cell)

Frequent co-authors in their work include Rahul Mannan, Xuhong Cao, Marcin Cieślik, Chandan Kumar-Sinha, and Somnath Mahapatra.

Publications have appeared repeatedly in several venues, such as Cancer Research, Nature Communications, Neoplasia, The Journal of Urology, and Cancer Cell.

Awards and honors received by the scientist include membership in the National Academy of Sciences (2020), Fellowship of the National Academy of Inventors (2014), Fellowship of the American Academy of Arts and Sciences (2014), the Paul Marks Prize for Cancer Research from Memorial Sloan Kettering Cancer Center (2009), membership in the National Academy of Medicine (2009), and membership in the Association of American Physicians.

Best Publications

  • Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

    S.A. Tomlins;D.R. Rhodes;S. Perner;S.M. Dhanasekaran

  • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

    Marta Muzio;Arul M. Chinnaiyan;Frank C. Kischkel;Karen O'Rourke

  • ONCOMINE: A Cancer Microarray Database and Integrated Data-Mining Platform

    Daniel R. Rhodes;Jianjun Yu;K. Shanker;Nandan Deshpande

  • Integrative clinical genomics of advanced prostate cancer

    Dan Robinson;Eliezer M. Van Allen;Eliezer M. Van Allen;Yi Mi Wu;Nikolaus Schultz

  • FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

    Arul M. Chinnaiyan;Karen O'Rourke;Muneesh Tewari;Vishva M. Dixit

  • The polycomb group protein EZH2 is involved in progression of prostate cancer

    Sooryanarayana Varambally;Saravana M. Dhanasekaran;Ming Zhou;Terrence R. Barrette

  • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

    Bin Zhao;Xiaomu Wei;Weiquan Li;Ryan S. Udan;Ryan S. Udan

  • The mutational landscape of lethal castration-resistant prostate cancer

    Catherine S. Grasso;Yi Mi Wu;Dan R. Robinson;Xuhong Cao

  • The landscape of long noncoding RNAs in the human transcriptome

    Matthew K. Iyer;Yashar S. Niknafs;Rohit Malik;Udit Singhal

  • CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

    Weimin Wang;Michael Green;Jae Eun Choi;Miguel Gijón

  • TEAD mediates YAP-dependent gene induction and growth control

    Bin Zhao;Xin Ye;Jindan Yu;Li Li;Li Li

  • Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

    Arun Sreekumar;Laila M. Poisson;Thekkelnaycke M. Rajendiran;Amjad P. Khan

  • The receptor for the cytotoxic ligand TRAIL

    Guohua Pan;Karen O'Rourke;Arul M. Chinnaiyan;Reiner Gentz

  • DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.

    Joaquin Mateo;Suzanne Carreira;Shahneen Sandhu;Susana Miranda

  • Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles.

    Daniel R. Rhodes;Shanker Kalyana-Sundaram;Vasudeva Mahavisno;Radhika Varambally

  • Delineation of prognostic biomarkers in prostate cancer

    Saravana M. Dhanasekaran;Terrence R. Barrette;Debashis Ghosh;Rajal Shah

  • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

    Celina G. Kleer;Qi Cao;Sooryanarayana Varambally;Ronglai Shen

  • The emergence of lncRNAs in cancer biology.

    John R. Prensner;Arul M. Chinnaiyan

  • Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

    Colin C. Pritchard;Joaquin Mateo;Michael F. Walsh;Navonil De Sarkar

  • Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

    Sooryanarayana Varambally;Qi Cao;Ram Shankar Mani;Sunita Shankar

Frequent Co-Authors

Xuhong Cao
Xuhong Cao University of Michigan–Ann Arbor
Scott A. Tomlins
Scott A. Tomlins University of Michigan–Ann Arbor
Rohit Mehra
Rohit Mehra University of Michigan–Ann Arbor
Mark A. Rubin
Mark A. Rubin University of Bern
Javed Siddiqui
Javed Siddiqui University of Michigan–Ann Arbor
Dan R. Robinson
Dan R. Robinson University of Michigan–Ann Arbor
Sooryanarayana Varambally
Sooryanarayana Varambally University of Alabama at Birmingham
Saravana M. Dhanasekaran
Saravana M. Dhanasekaran University of Michigan–Ann Arbor
Nallasivam Palanisamy
Nallasivam Palanisamy Henry Ford Health System
John T. Wei
John T. Wei University of Michigan–Ann Arbor

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