His scientific interests lie mostly in Molecular biology, Biochemistry, Matrix metalloproteinase, Immunology and Chemokine. His Molecular biology research incorporates elements of Interleukin 8, Complementary DNA, Peptide sequence, Gelatinase and Granulocyte. His Matrix metalloproteinase study combines topics from a wide range of disciplines, such as Extracellular, Extracellular matrix, Cell biology and Downregulation and upregulation.
As a member of one scientific family, Ghislain Opdenakker mostly works in the field of Cell biology, focusing on Proteases and, on occasion, Enzyme activator and Plasminogen activator. He frequently studies issues relating to Angiogenesis and Immunology. His studies in Chemokine integrate themes in fields like Chemotaxis and Monocyte.
Ghislain Opdenakker mostly deals with Immunology, Molecular biology, Matrix metalloproteinase, Biochemistry and Chemokine. His study connects Cancer research and Immunology. His Molecular biology research is multidisciplinary, incorporating elements of Cell culture, Gene, Gelatinase, Monocyte and Plasminogen activator.
His Gelatinase research integrates issues from Gelatinase A and Zymography. Ghislain Opdenakker interconnects Proteases, Pathology and Extracellular matrix, Cell biology in the investigation of issues within Matrix metalloproteinase. The concepts of his Chemokine study are interwoven with issues in Chemotaxis and Interleukin 8.
His main research concerns Immunology, Matrix metalloproteinase, Inflammation, Internal medicine and Angiogenesis. His Immunology study frequently draws parallels with other fields, such as Disease. The subject of his Matrix metalloproteinase research is within the realm of Biochemistry.
His Internal medicine research includes themes of Gastroenterology and Endocrinology. His research in Cell biology focuses on subjects like Chemotaxis, which are connected to Monocyte and Leukocyte migration. His Chemokine research is multidisciplinary, relying on both Serum amyloid A, Interleukin 8 and Experimental autoimmune encephalomyelitis.
His primary areas of investigation include Immunology, Matrix metalloproteinase, Inflammation, Proteases and Internal medicine. His research on Immunology frequently links to adjacent areas such as Cell biology. His Matrix metalloproteinase research is included under the broader classification of Biochemistry.
His research investigates the connection between Proteases and topics such as Autoimmunity that intersect with problems in Extracellular matrix. His research integrates issues of Gastroenterology and Endocrinology in his study of Internal medicine. His Chemokine research is multidisciplinary, incorporating perspectives in Serum amyloid A, Monocyte chemotaxis and Interleukin 8.
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Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9)
Philippe E. Van den Steen;Bénédicte Dubois;Inge Nelissen;Pauline M. Rudd.
Critical Reviews in Biochemistry and Molecular Biology (2002)
Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP-2 intact
Philippe Van den Steen;Paul Proost;Anja Wuyts;Jozef Van Damme.
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
Katrin Kierdorf;Daniel Erny;Tobias Goldmann;Victor Sander.
Nature Neuroscience (2013)
Concepts and Principles of O-Linked Glycosylation
Philippe Van den Steen;Pauline M. Rudd;Raymond A. Dwek;Ghislain Opdenakker.
Critical Reviews in Biochemistry and Molecular Biology (1998)
Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
Jialiang Hu;Philippe E. Van den Steen;Qing-Xiang A. Sang;Ghislain Opdenakker.
Nature Reviews Drug Discovery (2007)
Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.
J Van Damme;G Opdenakker;R J Simpson;M R Rubira.
Journal of Experimental Medicine (1987)
Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade
Jennifer Vandooren;Philippe E. Van den Steen;Ghislain Opdenakker.
Critical Reviews in Biochemistry and Molecular Biology (2013)
Gelatinase B functions as regulator and effector in leukocyte biology
Opdenakker G;Van den Steen Pe;Dubois B;Nelissen I.
Journal of Leukocyte Biology (2001)
Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis
Smriti Agrawal;Per Anderson;Madeleine Durbeej;Nico van Rooijen.
Journal of Experimental Medicine (2006)
Gelatinase B: a tuner and amplifier of immune functions
Ghislain Opdenakker;Philippe Van den Steen;Jozef Van Damme.
Trends in Immunology (2001)
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