World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
59
Citations
14331
World Ranking
3412
National Ranking
48

Overview

What is he best known for?

The fields of study he is best known for:

  • Cytokine
  • Gene
  • Immune system

Jozef Van Damme spends much of his time researching Immunology, Chemokine, Cell biology, Chemotaxis and Cytokine. His biological study spans a wide range of topics, including Demyelinating disease, Molecular biology and Interleukin 8. His work deals with themes such as Platelet factor 4, Endocrinology and CXC chemokine receptors, which intersect with Interleukin 8.

His work carried out in the field of Cell biology brings together such families of science as CX3CL1, CXCL2 and Neutrophil extravasation. His study with Chemotaxis involves better knowledge in Receptor. His research investigates the connection between Cytokine and topics such as Inflammation that intersect with issues in Cell migration, Cancer cell and Metastasis.

His most cited work include:

  • Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. (968 citations)
  • Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP-2 intact (590 citations)
  • The CC chemokine CCL20 and its receptor CCR6. (570 citations)

What are the main themes of his work throughout his whole career to date?

Immunology, Chemokine, Chemotaxis, Cell biology and Molecular biology are his primary areas of study. In his research, Endothelial stem cell is intimately related to Angiogenesis, which falls under the overarching field of Chemokine. His work on Chemotaxis is being expanded to include thematically relevant topics such as Monocyte.

His Cell biology research includes elements of Receptor, CXCL2, CCL13 and CCR1. The various areas that Jozef Van Damme examines in his Molecular biology study include Beta, Biochemistry, Messenger RNA and Gelatinase. His work in CXC chemokine receptors tackles topics such as CXCR3 which are related to areas like CXCL16, CX3CL1 and CXCL11.

He most often published in these fields:

  • Immunology (38.57%)
  • Chemokine (36.43%)
  • Chemotaxis (25.71%)

What were the highlights of his more recent work (between 2009-2017)?

  • Chemokine (36.43%)
  • Immunology (38.57%)
  • Cell biology (22.86%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Chemokine, Immunology, Cell biology, Angiogenesis and Chemotaxis. Jozef Van Damme has researched Chemokine in several fields, including Monocyte chemotaxis and Signal transduction. Many of his studies involve connections with topics such as Blood–brain barrier and Immunology.

The Cell biology study combines topics in areas such as CXCL2, Chemokine receptor, CCR1, Inflammation and Agonist. His Angiogenesis study integrates concerns from other disciplines, such as Platelet factor 4, Platelet and Molecular biology. Jozef Van Damme has included themes like Effector, Innate immune system and Monocyte in his Chemotaxis study.

Between 2009 and 2017, his most popular works were:

  • CXCR3 ligands in disease and therapy. (162 citations)
  • The role of the CXC chemokines platelet factor-4 (CXCL4/PF-4) and its variant (CXCL4L1/PF-4var) in inflammation, angiogenesis and cancer (99 citations)
  • Cytokine profiles in aqueous humor of patients with different clinical entities of endogenous uveitis. (92 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cytokine
  • Immune system

Jozef Van Damme focuses on Immunology, Chemokine, Cytokine, CXCR3 and Cell biology. His Immunology research is multidisciplinary, incorporating perspectives in Stromal cell and Neovascularization. His Chemotaxis research extends to the thematically linked field of Chemokine.

The concepts of his Cytokine study are interwoven with issues in Endothelial stem cell, Myofibroblast, Pathology, CD31 and Serum amyloid A. His CXCR3 research also works with subjects such as

  • Metastasis which is related to area like CXC chemokine receptors, Angiogenesis, Inflammation and Platelet factor 4,
  • CX3CL1, C-C chemokine receptor type 7 and Chemokine receptor CCR5 most often made with reference to CXCL16. His Cell biology study incorporates themes from CXCL2 and CCR1.

Best Publications

  • Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.

    Emmanuel Le Poul;Cecile Loison;Sofie Struyf;Jean-Yves Springael

  • The CC chemokine CCL20 and its receptor CCR6.

    Evemie Schutyser;Sofie Struyf;Jozef Van Damme

  • Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP-2 intact

    Philippe Van den Steen;Paul Proost;Anja Wuyts;Jozef Van Damme

  • The role of CXC chemokines and their receptors in cancer

    Jo Vandercappellen;Jozef Van Damme;Sofie Struyf

  • Gelatinase B: a tuner and amplifier of immune functions

    Ghislain Opdenakker;Philippe Van den Steen;Jozef Van Damme

  • The MCP/eotaxin subfamily of CC chemokines.

    Els Van Coillie;Jozef Van Damme;Ghislain Opdenakker

  • Production of interleukin-6 by folliculo-stellate cells of the anterior pituitary gland in a histiotypic cell aggregate culture system.

    Hugo Vankelecom;Peter Carmeliet;Jozef Van Damme;Alfons Billiau

  • CXCR3 ligands in disease and therapy.

    Katrien Van Raemdonck;Philippe Van den Steen;Sandra Liekens;Jozef Van Damme

  • Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes.

    Evemie Schutyser;Evemie Schutyser;Ann Richmond;Jozef Van Damme

  • Synergy in cytokine and chemokine networks amplifies the inflammatory response

    Mieke Gouwy;Sofie Struyf;Paul Proost;Jozef Van Damme

  • Identification of Biologically Active Chemokine Isoforms from Ascitic Fluid and Elevated Levels of CCL18/Pulmonary and Activation-regulated Chemokine in Ovarian Carcinoma

    Evemie Schutyser;Sofie Struyf;Paul Proost;Ghislain Opdenakker

  • Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation.

    Paul Proost;Tamara Loos;Anneleen Mortier;Evemie Schutyser

  • Murine CXCR1 Is a Functional Receptor for GCP-2/CXCL6 and Interleukin-8/CXCL8

    Xuedong Fan;Andriani C Patera;Amy Pong-Kennedy;Gregory Deno

  • Platelets Release CXCL4L1, a Nonallelic Variant of the Chemokine Platelet Factor-4/CXCL4 and Potent Inhibitor of Angiogenesis

    Sofie Struyf;Marie D Burdick;Paul Proost;Jozef Van Damme

  • Cytokines and proteases in invasive processes: molecular similarities between inflammation and cancer.

    Ghislain Opdenakker;Jozef Van Damme

  • Cleavage of denatured natural collagen type II by neutrophil gelatinase B reveals enzyme specificity, post-translational modifications in the substrate, and the formation of remnant epitopes in rheumatoid arthritis

    Philippe Van den Steen;Paul Proost;Bernard Grillet;David D Brand

  • GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors

    Klara Gijsbers;Mieke Gouwy;Sofie Struyf;Anja Wuyts

  • Chemokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy

    Ahmed M Abu El-Asrar;Sofie Struyf;Dustan Kangave;Karel Geboes

  • The role of the CXC chemokines platelet factor-4 (CXCL4/PF-4) and its variant (CXCL4L1/PF-4var) in inflammation, angiogenesis and cancer

    Jo Vandercappellen;Jozef Van Damme;Sofie Struyf

  • Cytokine profiles in aqueous humor of patients with different clinical entities of endogenous uveitis.

    Ahmed M Abu El-Asrar;Sofie Struyf;Dustan Kangave;Saleh S Al-Obeidan

  • Synergy between proinflammatory ligands of G protein-coupled receptors in neutrophil activation and migration

    Mieke Gouwy;Sofie Struyf;Julie Catusse;Paul Proost

Frequent Co-Authors

Ghislain Opdenakker
Ghislain Opdenakker Rega Institute for Medical Research
Sofie Struyf
Sofie Struyf KU Leuven
Paul Proost
Paul Proost KU Leuven
Alfons Billiau
Alfons Billiau Rega Institute for Medical Research
Karel Geboes
Karel Geboes Ghent University Hospital
Philippe E. Van den Steen
Philippe E. Van den Steen Rega Institute for Medical Research
Marc Parmentier
Marc Parmentier Université Libre de Bruxelles
Erik De Clercq
Erik De Clercq Rega Institute for Medical Research

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Related Online Degrees & Career Pathways

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