2026 William Vainchenker: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	129	430	385	6	6	729	55954
Medicine	128	2732	2547	69	64	740	55980

Research.com Recognitions

2026 - Research.com Biology and Biochemistry in France Leader Award
2025 - Research.com Biology and Biochemistry in France Leader Award
2023 - Research.com Biology and Biochemistry in France Leader Award
2023 - Research.com Medicine in France Leader Award
2022 - Research.com Biology and Biochemistry in France Leader Award
2014 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale

Overview

William Vainchenker is affiliated with the Institut Gustave Roussy in France and is primarily engaged in research within the field of Medicine. Their work focuses extensively on hematology, genetics, and molecular biology, with additional involvement in rheumatology and immunology.

Their research covers several main topics, including:

Myeloproliferative Neoplasms: Diagnosis and Treatment
Acute Myeloid Leukemia Research
Chronic Myeloid Leukemia Treatments
Kruppel-like factors research
Eosinophilic Disorders and Syndromes
Platelet Disorders and Treatments
Chronic Lymphocytic Leukemia Research

Recent notable publications by William Vainchenker include:

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution, 2023, Nature Genetics
Regulation of Platelet Production and Life Span: Role of Bcl-xL and Potential Implications for Human Platelet Diseases, 2020, International Journal of Molecular Sciences
Biological drivers of clinical phenotype in myelofibrosis, 2022, Leukemia
Functional Consequences of Mutations in Myeloproliferative Neoplasms, 2021, HemaSphere
Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms, 2021, Blood

Frequent co-authors in their body of work include:

Isabelle Plo
Caroline Marty
Hana Raslová
Jean-Jacques Kiladjian
Stefan N. Constantinescu

William Vainchenker's research has been published predominantly in journals and venues such as:

Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
Blood
Leukemia
Haematologica
HemaSphere

In 2014, William Vainchenker was awarded the Grand prix de l'Inserm from the Institut national de la santé et de la recherche médicale.

Best Publications

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Chloé James;Valérie Ugo;Jean-Pierre Le Couédic;Judith Staerk

4469
Citations
Mutation in TET2 in Myeloid Cancers

François Delhommeau;Sabrina Dupont;Véronique Della Valle;Chloé James

2112
Citations
TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

Cyril Quivoron;Cyril Quivoron;Cyril Quivoron;Lucile Couronné;Lucile Couronné;Lucile Couronné;Véronique Della Valle;Véronique Della Valle;Véronique Della Valle;Cécile K. Lopez;Cécile K. Lopez;Cécile K. Lopez

986
Citations
c-Mpl ligand is a humoral regulator of megakaryocytopoiesis

Françoise Wendling;Eugene Maraskovsky;Najet Debili;Christina Florindo

962
Citations
Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms

William Vainchenker;William Vainchenker;William Vainchenker;Robert Kralovics

593
Citations
JAK/STAT signaling in hematological malignancies

W. Vainchenker;W. Vainchenker;W. Vainchenker;Stefan N. Constantinescu;Stefan N. Constantinescu

585
Citations
TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

A. Tefferi;A. Pardanani;K. H. Lim;K. H. Lim;O. Abdel-Wahab

577
Citations
Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia

Raphaël Itzykson;Olivier Kosmider;Aline Renneville;Véronique Gelsi-Boyer

560
Citations
Oligodeoxynucleotides Antisense to the Proto-oncogene c-mpl Specifically Inhibit In Vitro Megakaryocytopoiesis

Nassia Methia;Fawzia Louache;William Vainchenker;FranCoise Wendling

543
Citations
JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis

Catherine Lacout;Didier F. Pisani;Didier F. Pisani;Micheline Tulliez;Micheline Tulliez;Françoise Moreau Gachelin;Françoise Moreau Gachelin

543
Citations
New mutations and pathogenesis of myeloproliferative neoplasms.

William Vainchenker;William Vainchenker;François Delhommeau;François Delhommeau;Stefan N. Constantinescu;Stefan N. Constantinescu;Olivier A. Bernard;Olivier A. Bernard;Olivier A. Bernard

502
Citations
Specific involvement of caspases in the differentiation of monocytes into macrophages.

Olivier Sordet;Cédric Rébé;Cédric Rébé;Cédric Rébé;Stéphanie Plenchette;Stéphanie Plenchette;Stéphanie Plenchette;Yaël Zermati;Yaël Zermati;Yaël Zermati

440
Citations
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs

Christophe Borg;Abdelali Jalil;Diego Laderach;Kouji Maruyama

433
Citations
Platelet formation is the consequence of caspase activation within megakaryocytes

Stephane de Botton;Siham Sabri;Eric Daugas;Yael Zermati

425
Citations
The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets.

N Debili;F Wendling;D Cosman;M Titeux

411
Citations
A murine stromal cell line allows the proliferation of very primitive human CD34++/CD38- progenitor cells in long-term cultures and semisolid assays

Cherifa Issaad;Laure Croisille;Andre Katz;William Vainchenker

409
Citations
Myeloproliferative Neoplasms: Molecular Pathophysiology, Essential Clinical Understanding, and Treatment Strategies

Ayalew Tefferi;William Vainchenker

409
Citations
The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors.

Najet Debili;Françoise Wendling;Andre Katz;Josette Guichard

406
Citations
Mutations of ASXL1 gene in myeloproliferative neoplasms

N Carbuccia;A Murati;V Trouplin;M Brecqueville

395
Citations
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy

Maria Castedo;Jean-Luc Perfettini;Thomas Roumier;Alexander Valent

384
Citations