D-Index & Metrics Best Publications
Biology and Biochemistry
France
2023
Medicine
France
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 118 Citations 45,983 628 World Ranking 2309 National Ranking 53
Biology and Biochemistry D-index 119 Citations 46,047 626 World Ranking 447 National Ranking 5

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in France Leader Award

2023 - Research.com Biology and Biochemistry in France Leader Award

2022 - Research.com Biology and Biochemistry in France Leader Award

2014 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

William Vainchenker mainly focuses on Immunology, Cell biology, Haematopoiesis, Molecular biology and Cancer research. His Immunology research focuses on Internal medicine and how it connects with Oncology. His Cell biology study incorporates themes from Apoptosis, Actin cytoskeleton and Cellular differentiation.

He interconnects Progenitor cell, CD34 and Myeloid in the investigation of issues within Haematopoiesis. His Molecular biology research is multidisciplinary, incorporating elements of Cell culture, Megakaryocyte, Gene expression and Antigen. His Cancer research study combines topics in areas such as Mutation, Missense mutation, Receptor, Janus kinase 2 and Myeloproliferative Disorders.

His most cited work include:

  • TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis (632 citations)
  • TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis (632 citations)
  • TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis (632 citations)

What are the main themes of his work throughout his whole career to date?

William Vainchenker spends much of his time researching Molecular biology, Immunology, Haematopoiesis, Cell biology and Cancer research. His studies deal with areas such as Cell culture, In vitro, Antigen and Antibody, Monoclonal antibody as well as Molecular biology. His Immunology research includes elements of Phenotype and Internal medicine.

The various areas that William Vainchenker examines in his Haematopoiesis study include Progenitor cell, CD34 and Myeloid. His Cell biology research integrates issues from Embryonic stem cell, Biochemistry and Cellular differentiation. His Cancer research research is multidisciplinary, incorporating perspectives in Mutation, Myelofibrosis, Myeloproliferative Disorders and Thrombopoietin receptor.

He most often published in these fields:

  • Molecular biology (34.35%)
  • Immunology (40.44%)
  • Haematopoiesis (35.19%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cancer research (36.04%)
  • Cell biology (38.58%)
  • Haematopoiesis (35.19%)

In recent papers he was focusing on the following fields of study:

William Vainchenker focuses on Cancer research, Cell biology, Haematopoiesis, Myelofibrosis and Calreticulin. His research integrates issues of Thrombopoietin receptor, Thrombopoietin, Myeloproliferative Disorders and Signal transduction in his study of Cancer research. His research investigates the link between Cell biology and topics such as Immunology that cross with problems in Mutation.

His study in Haematopoiesis is interdisciplinary in nature, drawing from both Progenitor cell, Downregulation and upregulation, Bone marrow and DNA repair. His biological study spans a wide range of topics, including Essential thrombocythemia, Polycythemia vera, Hematopoietic stem cell and Extramedullary hematopoiesis. His Calreticulin research incorporates themes from Molecular biology, Mutant, Cytokine receptor and Frameshift mutation.

Between 2013 and 2021, his most popular works were:

  • Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms (216 citations)
  • Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms (216 citations)
  • Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms (216 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

William Vainchenker mainly investigates Cancer research, Mutation, Calreticulin, Myelofibrosis and Cell biology. Downregulation and upregulation and Myeloid leukemia is closely connected to Haematopoiesis in his research, which is encompassed under the umbrella topic of Cancer research. His Mutation study integrates concerns from other disciplines, such as Cancer, Epigenetics and Chronic lymphocytic leukemia.

The Calreticulin study combines topics in areas such as Thrombopoietin receptor, Cytokine receptor and Essential thrombocythemia. His Essential thrombocythemia study is associated with Immunology. The concepts of his Cell biology study are interwoven with issues in MDia1 and Cytoskeleton.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Chloé James;Valérie Ugo;Jean-Pierre Le Couédic;Judith Staerk.
Nature (2005)

4251 Citations

Mutation in TET2 in Myeloid Cancers

François Delhommeau;Sabrina Dupont;Véronique Della Valle;Chloé James.
The New England Journal of Medicine (2009)

1987 Citations

c-Mpl ligand is a humoral regulator of megakaryocytopoiesis

Françoise Wendling;Eugene Maraskovsky;Najet Debili;Christina Florindo.
Nature (1994)

956 Citations

TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

Cyril Quivoron;Cyril Quivoron;Cyril Quivoron;Lucile Couronné;Lucile Couronné;Lucile Couronné;Véronique Della Valle;Véronique Della Valle;Véronique Della Valle;Cécile K. Lopez;Cécile K. Lopez;Cécile K. Lopez.
Cancer Cell (2011)

893 Citations

TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

A. Tefferi;A. Pardanani;K. H. Lim;K. H. Lim;O. Abdel-Wahab.
Leukemia (2009)

555 Citations

Oligodeoxynucleotides Antisense to the Proto-oncogene c-mpl Specifically Inhibit In Vitro Megakaryocytopoiesis

Nassia Methia;Fawzia Louache;William Vainchenker;FranCoise Wendling.
Blood (1993)

542 Citations

JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis

Catherine Lacout;Didier F. Pisani;Didier F. Pisani;Micheline Tulliez;Micheline Tulliez;Françoise Moreau Gachelin;Françoise Moreau Gachelin.
Blood (2006)

536 Citations

Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia

Raphaël Itzykson;Olivier Kosmider;Aline Renneville;Véronique Gelsi-Boyer.
Journal of Clinical Oncology (2013)

504 Citations

JAK/STAT signaling in hematological malignancies

W. Vainchenker;W. Vainchenker;W. Vainchenker;Stefan N. Constantinescu;Stefan N. Constantinescu.
Oncogene (2013)

502 Citations

New mutations and pathogenesis of myeloproliferative neoplasms.

William Vainchenker;William Vainchenker;François Delhommeau;François Delhommeau;Stefan N. Constantinescu;Stefan N. Constantinescu;Olivier A. Bernard;Olivier A. Bernard;Olivier A. Bernard.
Blood (2011)

489 Citations

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