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Microbiology

D-Index
54
Citations
11342
World Ranking
3941
National Ranking
10

Overview

Leonidas S. Tzouvelekis is affiliated with the National and Kapodistrian University of Athens in Greece. Their research spans fields primarily within Biochemistry, Genetics and Molecular Biology, with notable contributions to Medicine. Subfields of study include Molecular Medicine, Pharmacology, Applied Microbiology and Biotechnology, Clinical Biochemistry, and Biomedical Engineering.

The scientist's work focuses extensively on topics related to antibiotic resistance and bacterial infections. Key areas include:

  • Antibiotic Resistance in Bacteria
  • Antibiotics Pharmacokinetics and Efficacy
  • Antibiotic Use and Resistance
  • Bacterial Identification and Susceptibility Testing
  • Biosensors and Analytical Detection
  • Plant Pathogenic Bacteria Studies
  • Nosocomial Infections in ICU

Leonidas S. Tzouvelekis has collaborated with a number of frequent coauthors, including Vivì Miriagou, Stathis D. Kotsakis, Georgios Miliotis, Εva Tzelepi, and Evangelia Voulgari.

Representative recent publications highlight research on antibiotic resistance mechanisms and detection methods. Some of the papers include:

  • Detection in two hospitals of transferable ceftazidime-avibactam resistance in Klebsiella pneumoniae due to a novel VEB β-lactamase variant with a Lys234Arg substitution, Greece, 2019 (2020, Eurosurveillance)
  • Containing Carbapenemase-producing Klebsiella pneumoniae in an endemic setting (2020, Antimicrobial Resistance and Infection Control)
  • Evaluation of the performance of Acuitas® Resistome Test and the Acuitas Lighthouse® software for the detection of β-lactamase-producing microorganisms (2020, Journal of Global Antimicrobial Resistance)
  • Detection of carbapenemase producing enterobacteria using an ion sensitive field effect transistor sensor (2021, Scientific Reports)
  • Direct colorimetry of imipenem decomposition as a novel cost effective method for detecting carabapenamase producing bacteria (2022, bioRxiv (Cold Spring Harbor Laboratory))

The scientist publishes in journals including Eurosurveillance, Antimicrobial Resistance and Infection Control, Journal of Global Antimicrobial Resistance, Scientific Reports, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions

    L. S. Tzouvelekis;A. Markogiannakis;M. Psichogiou;P. T. Tassios

  • Carbapenemase-Producing Klebsiella pneumoniae Bloodstream Infections: Lowering Mortality by Antibiotic Combination Schemes and the Role of Carbapenems

    George L. Daikos;Sophia Tsaousi;Leonidas S. Tzouvelekis;Ioannis Anyfantis

  • CTX-M-type β-lactamases: an emerging group of extended-spectrum enzymes

    L.S Tzouvelekis;E Tzelepi;P.T Tassios;N.J Legakis

  • Treating infections caused by carbapenemase-producing Enterobacteriaceae

    L.S. Tzouvelekis;A. Markogiannakis;E. Piperaki;M. Souli

  • Imipenem Resistance in a Salmonella Clinical Strain Due to Plasmid-Mediated Class A Carbapenemase KPC-2

    Vivi Miriagou;Leonidas S. Tzouvelekis;Shannon Rossiter;Eva Tzelepi

  • Prospective Observational Study of the Impact of VIM-1 Metallo-β-Lactamase on the Outcome of Patients with Klebsiella pneumoniae Bloodstream Infections

    George L. Daikos;Panayiotis Petrikkos;Mina Psichogiou;Chris Kosmidis

  • Interventional strategies and current clinical experience with carbapenemase-producing Gram-negative bacteria

    M. Akova;G.L. Daikos;L. Tzouvelekis;Y. Carmeli

  • VIM-1 Metallo-β-Lactamase-Producing Klebsiella pneumoniae Strains in Greek Hospitals

    P. Giakkoupi;A. Xanthaki;M. Kanelopoulou;A. Vlahaki

  • An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009–10)

    Panagiota Giakkoupi;Costas C Papagiannitsis;Vivi Miriagou;Olga Pappa

  • Carbapenem-resistant Acinetobacter baumannii: in pursuit of an effective treatment.

    E.-T. Piperaki;L.S. Tzouvelekis;V. Miriagou;G.L. Daikos

  • Escherichia coli with a Self-Transferable, Multiresistant Plasmid Coding for Metallo-β-Lactamase VIM-1

    Vivi Miriagou;Eva Tzelepi;Dimitra Gianneli;Leonidas S. Tzouvelekis

  • Emergence of an inhibitor-resistant beta-lactamase (SHV-10) derived from an SHV-5 variant.

    E E Prinarakis;V Miriagou;E Tzelepi;M Gazouli

  • Expanded-spectrum cephalosporin resistance in non-typhoid Salmonella

    V Miriagou;P.T Tassios;N.J Legakis;L.S Tzouvelekis

  • Hospital outbreak of multiple clones of Pseudomonas aeruginosa carrying the unrelated metallo-β-lactamase gene variants blaVIM-2 and blaVIM-4

    S Pournaras;M Maniati;E Petinaki;L S Tzouvelekis

  • Klebsiella pneumoniae: Virulence, Biofilm and Antimicrobial Resistance.

    Evangelia-Theophano Piperaki;George A. Syrogiannopoulos;Leonidas S. Tzouvelekis;George L. Daikos

  • IBC-1, a novel integron-associated class A beta-lactamase with extended-spectrum properties produced by an Enterobacter cloacae clinical strain.

    Panagiota Giakkoupi;Leonidas S. Tzouvelekis;Athanassios Tsakris;Veneta Loukova;Veneta Loukova

  • SHV-type beta-lactamases.

    Leonidas S. Tzouvelekis;Robert A Bonomo

  • Ongoing epidemic of blaVIM-1-positive Klebsiella pneumoniae in Athens, Greece: a prospective survey

    M. Psichogiou;P. T. Tassios;A. Avlamis;I. Stefanou

  • VIM-1 Metallo-β-lactamase in Acinetobacter baumannii

    Athanassios Tsakris;Alexandros Ikonomidis;Spyros Pournaras;Leonidas S. Tzouvelekis

  • Novel Variant (blaVIM-4) of the Metallo-β-Lactamase Gene blaVIM-1 in a Clinical Strain of Pseudomonas aeruginosa

    Spyros Pournaras;Athanassios Tsakris;Maria Maniati;Leonidas S. Tzouvelekis

  • Novel GES/IBC extended‐spectrum β‐lactamase variants with carbapenemase activity in clinical enterobacteria

    Sofia Vourli;Panagiota Giakkoupi;Vivi Miriagou;Eva Tzelepi

Frequent Co-Authors

Vivi Miriagou
Vivi Miriagou Institut Pasteur
George L. Daikos
George L. Daikos National and Kapodistrian University of Athens
Athanassios Tsakris
Athanassios Tsakris National and Kapodistrian University of Athens
Spyros Pournaras
Spyros Pournaras National and Kapodistrian University of Athens
Alessandra Carattoli
Alessandra Carattoli Sapienza University of Rome
Joseph Meletiadis
Joseph Meletiadis National and Kapodistrian University of Athens
Laura Villa
Laura Villa Istituto Superiore di Sanità
Guillaume Arlet
Guillaume Arlet Sorbonne University
Maria Gazouli
Maria Gazouli National and Kapodistrian University of Athens
Roger Stephan
Roger Stephan University of Zurich

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