John H. Exton

Research.com Recognitions

• 2001 - Member of the National Academy of Sciences
• 1999 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Signaling through phosphatidylcholine breakdown.

  J H Exton

  1932
  Citations

• Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

  H. Nakanishi;K.A. Brewer;J.H. Exton

  1407
  Citations

• Phosphatidylcholine breakdown and signal transduction

  J.H. Exton

  1331
  Citations

• Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins.

  Stephen J. Taylor;Ho Zoon Chae;Sue Goo Rhee;John H. Exton

  1090
  Citations

• Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression

  Ping Hu;Zhang Han;Anthony D. Couvillon;Randal J. Kaufman

  1005
  Citations

• Regulation of phospholipase D.

  John H Exton

  875
  Citations

• Control of gluconeogenesis in liver. I. General features of gluconeogenesis in the perfused livers of rats.

  J.H. Exton;C.R. Park

  651
  Citations

• Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator

  Gabriel Berstein;Jonathan L. Blank;Deok Young Jhon;John H. Exton

  610
  Citations

• Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism.

  S B Bocckino;P F Blackmore;P B Wilson;J H Exton

  607
  Citations

• A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes

  Timothy M. Chan;John H. Exton

  583
  Citations

• Phospholipase D: enzymology, mechanisms of regulation, and function

  J. H. Exton

  578
  Citations

• Control of Gluconeogenesis from Amino Acids in the Perfused Rat Liver

  L.E. Mallette;J.H. Exton;C.R. Park

  569
  Citations

• Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.

  R J Uhing;V Prpic;H Jiang;J H Exton

  489
  Citations

• Changes in free cytosolic Ca2+ in hepatocytes following alpha 1-adrenergic stimulation. Studies on Quin-2-loaded hepatocytes.

  R Charest;P F Blackmore;B Berthon;J H Exton

  487
  Citations

• Studies on the alpha-adrenergic activation of hepatic glucose output. I. Studies on the alpha-adrenergic activation of phosphorylase and gluconeogenesis and inactivation of glycogen synthase in isolated rat liver parenchymal cells.

  N J Hutson;F T Brumley;F D Assimacopoulos;S C Harper

  466
  Citations

• Critical Role of Endogenous Akt/IAPs and MEK1/ERK Pathways in Counteracting Endoplasmic Reticulum Stress-induced Cell Death

  Ping Hu;Zhang Han;Anthony D. Couvillon;John H. Exton

  457
  Citations

• New developments in phospholipase D

  John H. Exton

  449
  Citations

• Studies on the role of adenosine 3',5'-monophosphate in the hepatic actions of glucagon and catecholamines.

  J.H. Exton;G.A. Robison;Earl W. Sutherland;C.R. Park

  436
  Citations

• Role of Adenosine 3',5'-Monophosphate in the Effects of Insulin and Anti-insulin Serum on Liver Metabolism

  L. S. Jefferson;J. H. Exton;R. W. Butcher;Earl W. Sutherland

  432
  Citations

• Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

  Gabriel Berstein;Jonathan L. Blank;Alan V. Smrcka;Tsutomu Higashijima

  423
  Citations