His primary scientific interests are in Biochemistry, Cell biology, Phosphatidylinositol, Signal transduction and Intracellular. His work is connected to Inositol, Receptor, Phospholipase C, Lipidomics and In vitro, as a part of Biochemistry. His Cell biology research is multidisciplinary, relying on both Phospholipase and Lysophosphatidic acid.
His work in the fields of Phosphatidylinositol, such as Wortmannin, overlaps with other areas such as Human platelet. His Signal transduction research is multidisciplinary, incorporating perspectives in Tumor necrosis factor alpha, Extracellular, Phospholipase D activity, Leukotriene B4 and Adenylate kinase. The study incorporates disciplines such as Lipid signaling, Phosphatidic acid, Yeast, Liquid chromatography–mass spectrometry and Lipid microdomain in addition to Intracellular.
His primary areas of investigation include Cell biology, Biochemistry, Internal medicine, Phospholipase D and Endocrinology. His Cell biology research is multidisciplinary, incorporating elements of Receptor and Phosphatidic acid. His Biochemistry research focuses on Inositol, Phosphatidylcholine, Phospholipase, Diacylglycerol kinase and Phosphatidylinositol.
The Inositol study combines topics in areas such as Phospholipid and Cyclase. Michael J.O. Wakelam has researched Phospholipase D in several fields, including Phosphatidate, Phospholipase D activity, Molecular biology, Protein kinase C and PLD2. As a part of the same scientific family, Michael J.O. Wakelam mostly works in the field of Molecular biology, focusing on Cell culture and, on occasion, Stimulation.
His main research concerns Cell biology, Biochemistry, Lipidomics, Internal medicine and Computational biology. The various areas that he examines in his Cell biology study include Autophagy, Receptor and Membrane. Biochemistry and Cancer cell are commonly linked in his work.
His work on Lipidome as part of general Lipidomics study is frequently connected to Context, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His study explores the link between Internal medicine and topics such as Endocrinology that cross with problems in Longevity. His Computational biology research focuses on Mass spectrometric and how it connects with Glycerophospholipids.
His scientific interests lie mostly in Biochemistry, Cell biology, Lipidomics, Cancer cell and Fatty acid. In his research, Michael J.O. Wakelam undertakes multidisciplinary study on Biochemistry and Visual phototransduction. Michael J.O. Wakelam performs multidisciplinary studies into Cell biology and Yolk in his work.
His work carried out in the field of Lipidomics brings together such families of science as Computational biology and Mass spectrometric. His research in Cancer cell intersects with topics in Cell migration, Contact inhibition, Cell growth, Gene silencing and Lipid biosynthesis. His studies examine the connections between Fatty acid and genetics, as well as such issues in Lipid droplet, with regards to Phospholipase D, Triglyceride, Molecular biology, Virion assembly and Cholesterol.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Update of the LIPID MAPS comprehensive classification system for lipids
Eoin Fahy;Shankar Subramaniam;Robert C. Murphy;Masahiro Nishijima.
Journal of Lipid Research (2009)
Shorthand notation for lipid structures derived from mass spectrometry
Gerhard Liebisch;Juan Antonio Vizcaíno;Harald Köfeler;Martin Trötzmüller.
Journal of Lipid Research (2013)
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.
Laurens A. van Meeteren;Paula Ruurs;Catelijne Stortelers;Peter Bouwman.
Molecular and Cellular Biology (2006)
Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Zachary T. Schug;Barrie Peck;Dylan T. Jones;Qifeng Zhang.
Cancer Cell (2015)
Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production.
Michael J. O. Wakelam;Shireen A. Davies;Miles D. Houslay;Ian McKay.
Nature (1986)
Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
Karim Bensaad;Elena Favaro;Caroline A. Lewis;Barrie Peck.
Cell Reports (2014)
Activation of two signal-transduction systems in hepatocytes by glucagon
Michael J. O. Wakelam;Gregory J. Murphy;Victor J. Hruby;Miles D. Houslay.
Nature (1986)
Wortmannin and Its Structural Analogue Demethoxyviridin Inhibit Stimulated Phospholipase A2 Activity in Swiss 3T3 Cells: WORTMANNIN IS NOT A SPECIFIC INHIBITOR OF PHOSPHATIDYLINOSITOL 3-KINASE
Michael J. Cross;Allison Stewart;Matthew N. Hodgkin;David J. Kerr.
Journal of Biological Chemistry (1995)
The fusion of myoblasts
M. J. O. Wakelam.
Biochemical Journal (1985)
Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?
Matthew N Hodgkin;Trevor R Pettitt;Ashley Martin;Robert H Michell.
Trends in Biochemical Sciences (1998)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
Mironid Limited
University of Strathclyde
University of Oxford
University of Oxford
University of Oxford
University of Glasgow
German Cancer Research Center
University of Konstanz
Cardiff University
Max Planck Society
Deakin University
University of Paris-Saclay
IBM (United States)
Alibaba Group (China)
Pusan National University
University of Rostock
University of California, Riverside
Catholic University of the Sacred Heart
National Institutes of Health
National Institute for Basic Biology
University of Modena and Reggio Emilia
New York University
Memorial Sloan Kettering Cancer Center
Touro College
University of Bergen
University of Alabama at Birmingham