World's Best Scientists 2026 revealed!
Michael J. O. Wakelam

Michael J. O. Wakelam

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
24315
World Ranking
3885
National Ranking
286

Overview

Michael J. O. Wakelam was affiliated with the Babraham Institute in the United Kingdom. Their research primarily focused on biochemistry, genetics, and molecular biology, having contributed to 31 publications within these fields. Medicine also featured prominently in their work, with 22 publications attributed to this area of study.

The scientist's work spanned several subfields, including molecular biology, spectroscopy, physiology, aging, and cancer research. Their research topics covered metabolomics and mass spectrometry studies, advanced proteomics techniques, genetics and aging in model organisms, adipose tissue and metabolism, mass spectrometry techniques and applications, the effects of spaceflight on biology, and cancer, lipids, and metabolism.

Frequent coauthors included Andrea F. Lopez-Clavijo, Bebiana C. Sousa, Valerie B. O'Donnell, Greg West, and Maria Fedorova. Publication venues where their work appeared multiple times were Zenodo (CERN European Organization for Nuclear Research), Nature Communications, F1000Research, the Journal of Lipid Research, and Molecular Cell.

Notable recent papers were:

  • Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures (2020), Journal of Lipid Research
  • Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine (2021), Molecular Cell
  • Potential Role of Oral Rinses Targeting the Viral Lipid Envelope in SARS-CoV-2 Infection (2020), Function
  • Quality control requirements for the correct annotation of lipidomics data (2021), Nature Communications
  • BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS (2021), F1000Research

Best Publications

  • Update of the LIPID MAPS comprehensive classification system for lipids

    Eoin Fahy;Shankar Subramaniam;Robert C. Murphy;Masahiro Nishijima

  • Shorthand notation for lipid structures derived from mass spectrometry

    Gerhard Liebisch;Juan Antonio Vizcaíno;Harald Köfeler;Martin Trötzmüller

  • Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures

    Gerhard Liebisch;Eoin Fahy;Junken Aoki;Edward A. Dennis

  • Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

    Zachary T. Schug;Barrie Peck;Dylan T. Jones;Qifeng Zhang

  • Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.

    Laurens A. van Meeteren;Paula Ruurs;Catelijne Stortelers;Peter Bouwman

  • Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation

    Karim Bensaad;Elena Favaro;Caroline A. Lewis;Barrie Peck

  • Activation of two signal-transduction systems in hepatocytes by glucagon

    Michael J. O. Wakelam;Gregory J. Murphy;Victor J. Hruby;Miles D. Houslay

  • Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production.

    Michael J. O. Wakelam;Shireen A. Davies;Miles D. Houslay;Ian McKay

  • The fusion of myoblasts

    M. J. O. Wakelam

  • Wortmannin and Its Structural Analogue Demethoxyviridin Inhibit Stimulated Phospholipase A2 Activity in Swiss 3T3 Cells: WORTMANNIN IS NOT A SPECIFIC INHIBITOR OF PHOSPHATIDYLINOSITOL 3-KINASE

    Michael J. Cross;Allison Stewart;Matthew N. Hodgkin;David J. Kerr

  • Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

    Matthew N Hodgkin;Trevor R Pettitt;Ashley Martin;Robert H Michell

  • Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA

    Marjorie J Lindhurst;Victoria E R Parker;Felicity Payne;Julie C Sapp

  • Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry

    Jonathan Clark;Karen E Anderson;Veronique Juvin;Trevor S Smith

  • Identification of serum biomarkers for colon cancer by proteomic analysis.

    D G Ward;N Suggett;Y Cheng;W Wei

  • Stimulation of actin stress fibre formation mediated by activation of phospholipase D.

    Michael J. Cross;Sally Roberts;Anne J. Ridley;Matthew N. Hodgkin

  • Diacylglycerol and Phosphatidate Generated by Phospholipases C and D, Respectively, Have Distinct Fatty Acid Compositions and Functions PHOSPHOLIPASE D-DERIVED DIACYLGLYCEROL DOES NOT ACTIVATE PROTEIN KINASE C IN PORCINE AORTIC ENDOTHELIAL CELLS

    Trevor R. Pettitt;Ashley Martin;Tracy Horton;Christos Liossis

  • MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines

    Bo Burla;Makoto Arita;Makoto Arita;Masanori Arita;Anne K. Bendt

  • PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity

    Aparna Pal;Thomas M. Barber;Martijn Van de Bunt;Simon A. Rudge

  • Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth

    Beatrice Griffiths;Caroline A Lewis;Caroline A Lewis;Karim Bensaad;Susana Ros

  • Extracellular vesicles: lipids as key components of their biogenesis and functions.

    Michel Record;Sandrine Silvente-Poirot;Marc Poirot;Michael J. O. Wakelam

Frequent Co-Authors

Robin Plevin
Robin Plevin University of Strathclyde
Miles D. Houslay
Miles D. Houslay King's College London
David J. Kerr
David J. Kerr University of Oxford
Fredrik Karpe
Fredrik Karpe University of Oxford
adrian l harris
adrian l harris University of Oxford
Almut Schulze
Almut Schulze German Cancer Research Center
Graeme Milligan
Graeme Milligan University of Glasgow
Dirk Pette
Dirk Pette University of Konstanz
Valerie B. O'Donnell
Valerie B. O'Donnell Cardiff University
Linda Partridge
Linda Partridge Max Planck Society

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