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D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
10248
World Ranking
17551
National Ranking
1383

Overview

Robin Plevin is affiliated with the University of Strathclyde in the United Kingdom. Their research spans multiple fields, primarily focusing on medicine, immunology and microbiology, as well as biochemistry, genetics, and molecular biology.

The scientist's work broadly involves investigation into immune response and inflammation, with a specific focus on NF-κB signaling pathways. Their research topics include interferon and immune responses, cytokine signaling pathways and interactions, blood coagulation and thrombosis mechanisms, coagulation involving bradykinin and polyphosphates, and heparin-induced thrombocytopenia and thrombosis.

Recent publications authored or co-authored by Robin Plevin include:

  • The development of proteinase-activated receptor-2 modulators and the challenges involved (2020, Biochemical Society Transactions)
  • Targeting 17β-estradiol biosynthesis in neural stem cells improves stroke outcome (2022, Frontiers in Cellular Neuroscience)
  • Design and Synthesis of Novel Aminoindazole-pyrrolo[2,3-b]pyridine Inhibitors of IKKα That Selectively Perturb Cellular Non-Canonical NF-κB Signalling (2024, Molecules)
  • IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling (2023, Cellular Signalling)
  • Determining the prognostic significance of IKKα in prostate cancer (2020, The Prostate)

Their frequent co-authors include Kathryn McIntosh, Andrew Paul, Simon P. Mackay, Christopher P. Lawson, and Rachel Craig. The collaboration appears consistently in various studies involving NF-κB and immune signaling pathways.

Robin Plevin has published in a variety of journals including Biochemical Society Transactions, Frontiers in Cellular Neuroscience, Molecules, Cellular Signalling, and the Journal of Clinical Investigation.

The scientist's subfields of study reflect a focus on immunology, cancer research, neurology, genetics, and cellular and molecular neuroscience.

Best Publications

  • Proteinase-Activated Receptors

    Scott R. Macfarlane;Michael J. Seatter;Toru Kanke;Gary D. Hunter

  • Essential role for proteinase-activated receptor-2 in arthritis

    William R. Ferrell;John C. Lockhart;Elizabeth B. Kelso;Lynette Dunning

  • Stress-activated protein kinases: activation, regulation and function.

    Andrew Paul;Susan Wilson;Christopher M Belham;Caspar J.M Robinson

  • The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors.

    K Malarkey;C M Belham;A Paul;A Graham

  • Vascular endothelial growth factor receptor localization and activation in human trophoblast and choriocarcinoma cells.

    D. S. Charnock-Jones;A. M. Sharkey;C. A. Boocock;Asif Ahmed

  • MAP kinase phosphatase 2 deficient mice develop attenuated experimental autoimmune encephalomyelitis through regulating dendritic cells and T cells

    Mark Barbour;Robin Plevin;Hui-Rong Jiang

  • Therapeutic Promise of Proteinase-Activated Receptor-2 Antagonism in Joint Inflammation

    Elizabeth B. Kelso;John C. Lockhart;Todd Hembrough;Lynette Dunning

  • Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway

    Pamela Cameron;Adrienne McGachy;Mary Anderson;Andrew Paul

  • The annexin protein lipocortin 1 regulates the MAPK/ERK pathway.

    Louise C. Alldridge;Hayley J. Harris;Robin Plevin;Robert Hannon

  • Growth factors, mitogens, oncogenes and the regulation of glucose transport.

    Nicola W. Merrall;Robin Plevin;Gwyn W. Gould

  • A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells.

    Pamela H Scott;Christopher M Belham;Jenan Al-Hafidh;Edwin R. Chilvers

  • Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.

    Vera P. Krymskaya;Raymond B. Penn;Michael J. Orsini;Pamela H. Scott

  • Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes.

    Toru Kanke;Scott R. Macfarlane;Michael J. Seatter;Emma Davenport

  • The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages.

    S Hatziieremia;A I Gray;V A Ferro;A Paul

  • Involvement of Mitogen-Activated Protein Kinase Homologues in the Regulation of Lipopolysaccharide-Mediated Induction of Cyclo-oxygenase-2 but not Nitric Oxide Synthase in RAW 264.7 Macrophages

    Andrew Paul;Ana Cuenda;Clare E. Bryant;Jo Murray

  • Inhibitory kappa B kinases as targets for pharmacological regulation

    Carly Gamble;Kathryn McIntosh;Rebecca Scott;Ka Ho Ho

  • Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock.

    Michelle C. McDONALD;Helder Mota-Filipe;Andrew Paul;Salvatore Cuzzocrea

  • PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases.

    T. K. Monaghan;C. J. MacKenzie;R. Plevin;E. M. Lutz

  • Protein kinase C and tyrosine kinase pathways regulate lipopolysaccharide-induced nitric oxide synthase activity in RAW 264.7 murine macrophages.

    Andrew Paul;Robert H Pendreigh;Robin Plevin

  • Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D.

    R Plevin;S J Cook;S Palmer;M J O Wakelam

Frequent Co-Authors

Gwyn W. Gould
Gwyn W. Gould University of Strathclyde
Michael J. O. Wakelam
Michael J. O. Wakelam Babraham Institute
James Alexander
James Alexander Centers for Disease Control and Prevention
Iain B. McInnes
Iain B. McInnes University of Glasgow
Edwin R. Chilvers
Edwin R. Chilvers Imperial College London
Clare E. Bryant
Clare E. Bryant University of Cambridge
Andrew D. Rowan
Andrew D. Rowan Newcastle University
Stephen K. Smith
Stephen K. Smith University of Cambridge
Richard Leduc
Richard Leduc Université de Sherbrooke
Craig W. Roberts
Craig W. Roberts University of Strathclyde

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