D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 45 Citations 6,265 140 World Ranking 12911 National Ranking 356
Biology and Biochemistry D-index 51 Citations 6,990 154 World Ranking 12825 National Ranking 438

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Amino acid
  • Biochemistry

His primary areas of investigation include Biochemistry, Furin, Peptide, Receptor and Cell biology. Richard Leduc undertakes multidisciplinary investigations into Biochemistry and ADAMTS in his work. His Furin research is multidisciplinary, relying on both Transforming growth factor beta and Zymogen.

His Peptide research incorporates elements of Amino acid and Cleavage. His work on Angiotensin II and Transcytosis as part of general Receptor study is frequently linked to Chronic pain, therefore connecting diverse disciplines of science. His Cell biology study incorporates themes from Matrix metalloproteinase, Collagenase and Pathology.

His most cited work include:

  • Processing of transforming growth factor beta 1 precursor by human furin convertase. (342 citations)
  • Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1. (274 citations)
  • Evidence that Furin Is an Authentic Transforming Growth Factor-β1-Converting Enzyme (191 citations)

What are the main themes of his work throughout his whole career to date?

Richard Leduc mostly deals with Biochemistry, Receptor, Cell biology, Angiotensin II and Angiotensin II receptor type 1. His study in Furin, Enzyme, Peptide, Amino acid and Serine is done as part of Biochemistry. His biological study spans a wide range of topics, including Stereochemistry and Binding site.

His Cell biology study integrates concerns from other disciplines, such as Internalization, Matriptase and Endosome. His studies in Angiotensin II integrate themes in fields like Biophysics and G protein. His work deals with themes such as Molecular model and Phospholipase C, which intersect with Angiotensin II receptor type 1.

He most often published in these fields:

  • Biochemistry (46.75%)
  • Receptor (42.86%)
  • Cell biology (24.68%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (24.68%)
  • Receptor (42.86%)
  • Signal transduction (9.74%)

In recent papers he was focusing on the following fields of study:

Richard Leduc spends much of his time researching Cell biology, Receptor, Signal transduction, G protein-coupled receptor and Matriptase. His work on Gs alpha subunit as part of general Cell biology study is frequently connected to Ubiquitin, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. The concepts of his Receptor study are interwoven with issues in Cancer research, Stereochemistry, Bioinformatics and DOTA.

His G protein-coupled receptor research also works with subjects such as

  • Angiotensin II and related Functional selectivity and HEK 293 cells,
  • Biophysics that connect with fields like Agonist. The various areas that Richard Leduc examines in his Matriptase study include Proteases, Matrix metalloproteinase and Serine. Peptidomimetic is the subject of his research, which falls under Biochemistry.

Between 2016 and 2021, his most popular works were:

  • Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors (42 citations)
  • The signaling signature of the neurotensin type 1 receptor with endogenous ligands (31 citations)
  • Structure–activity relationship of novel macrocyclic biased apelin receptor agonists (16 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Amino acid
  • Internal medicine

His primary scientific interests are in Cell biology, Matriptase, G protein, Signal transduction and Matrix metalloproteinase. His work in Cell biology addresses issues such as Serine protease, which are connected to fields such as Proteases. His study in G protein is interdisciplinary in nature, drawing from both Arrestin, Vascular resistance, Blood pressure, Inotrope and Pharmacology.

His Signal transduction study combines topics in areas such as Angiotensin II and Effector. His research integrates issues of Extracellular, Extracellular matrix, Serine and Hepsin in his study of Matrix metalloproteinase. Richard Leduc incorporates a variety of subjects into his writings, including Aggrecan, Blot, In vitro, Osteoarthritis and Metalloproteinase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Processing of transforming growth factor beta 1 precursor by human furin convertase.

Claire M. Dubois;Marie-Hélène Laprise;François Blanchette;Larry E. Gentry.
Journal of Biological Chemistry (1995)

588 Citations

Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.

Robert P.T. Somerville;Jean-Michel Longpre;Katherine A. Jungers;J. Michael Engle.
Journal of Biological Chemistry (2003)

375 Citations

Evidence that Furin Is an Authentic Transforming Growth Factor-β1-Converting Enzyme

Claire M. Dubois;François Blanchette;Marie-Hélène Laprise;Richard Leduc.
American Journal of Pathology (2001)

294 Citations

Ligand-Induced Signaling in the Absence of Furin Processing of Notch1

Guy diSibio;Alison Miyamoto;Jean-Bernard Denault.
Developmental Biology (2001)

182 Citations

Processing of proendothelin-1 by human furin convertase

Jean-Bernard Denault;Audrey Claing;Pedro D'Orléans-Juste;Tatsuya Sawamura.
FEBS Letters (1995)

165 Citations

Characterization of proADAMTS5 processing by proprotein convertases.

Jean Michel Longpré;Daniel R. McCulloch;Bon Hun Koo;J. Preston Alexander.
The International Journal of Biochemistry & Cell Biology (2009)

131 Citations

Polyethylene Glycol Conjugation at Cys232 Prolongs the Half-Life of α1 Proteinase Inhibitor

André M. Cantin;Donald E. Woods;Diane Cloutier;Erick K. Dufour.
American Journal of Respiratory Cell and Molecular Biology (2002)

129 Citations

Inhibitory Potency and Specificity of Subtilase-like Pro-protein Convertase (SPC) Prodomains

Martin Fugère;Polizois C. Limperis;Véronique Beaulieu-Audy;Frédéric Gagnon.
Journal of Biological Chemistry (2002)

124 Citations

ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain.

Robert P T Somerville;Jean Michel Longpré;Elizabeth D. Apel;Renate M. Lewis.
Journal of Biological Chemistry (2004)

122 Citations

A Polyaromatic Caveolin-Binding-Like Motif in the Cytoplasmic Tail of the Type 1 Receptor for Angiotensin II Plays an Important Role in Receptor Trafficking and Signaling

Patrice C. Leclerc;Mannix Auger-Messier;Pascal M. Lanctot;Emanuel Escher.
Endocrinology (2002)

119 Citations

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