His primary areas of investigation include Biochemistry, Furin, Peptide, Receptor and Cell biology. Richard Leduc undertakes multidisciplinary investigations into Biochemistry and ADAMTS in his work. His Furin research is multidisciplinary, relying on both Transforming growth factor beta and Zymogen.
His Peptide research incorporates elements of Amino acid and Cleavage. His work on Angiotensin II and Transcytosis as part of general Receptor study is frequently linked to Chronic pain, therefore connecting diverse disciplines of science. His Cell biology study incorporates themes from Matrix metalloproteinase, Collagenase and Pathology.
Richard Leduc mostly deals with Biochemistry, Receptor, Cell biology, Angiotensin II and Angiotensin II receptor type 1. His study in Furin, Enzyme, Peptide, Amino acid and Serine is done as part of Biochemistry. His biological study spans a wide range of topics, including Stereochemistry and Binding site.
His Cell biology study integrates concerns from other disciplines, such as Internalization, Matriptase and Endosome. His studies in Angiotensin II integrate themes in fields like Biophysics and G protein. His work deals with themes such as Molecular model and Phospholipase C, which intersect with Angiotensin II receptor type 1.
Richard Leduc spends much of his time researching Cell biology, Receptor, Signal transduction, G protein-coupled receptor and Matriptase. His work on Gs alpha subunit as part of general Cell biology study is frequently connected to Ubiquitin, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. The concepts of his Receptor study are interwoven with issues in Cancer research, Stereochemistry, Bioinformatics and DOTA.
His G protein-coupled receptor research also works with subjects such as
His primary scientific interests are in Cell biology, Matriptase, G protein, Signal transduction and Matrix metalloproteinase. His work in Cell biology addresses issues such as Serine protease, which are connected to fields such as Proteases. His study in G protein is interdisciplinary in nature, drawing from both Arrestin, Vascular resistance, Blood pressure, Inotrope and Pharmacology.
His Signal transduction study combines topics in areas such as Angiotensin II and Effector. His research integrates issues of Extracellular, Extracellular matrix, Serine and Hepsin in his study of Matrix metalloproteinase. Richard Leduc incorporates a variety of subjects into his writings, including Aggrecan, Blot, In vitro, Osteoarthritis and Metalloproteinase.
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Processing of transforming growth factor beta 1 precursor by human furin convertase.
Claire M. Dubois;Marie-Hélène Laprise;François Blanchette;Larry E. Gentry.
Journal of Biological Chemistry (1995)
Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.
Robert P.T. Somerville;Jean-Michel Longpre;Katherine A. Jungers;J. Michael Engle.
Journal of Biological Chemistry (2003)
Evidence that Furin Is an Authentic Transforming Growth Factor-β1-Converting Enzyme
Claire M. Dubois;François Blanchette;Marie-Hélène Laprise;Richard Leduc.
American Journal of Pathology (2001)
Ligand-Induced Signaling in the Absence of Furin Processing of Notch1
Guy diSibio;Alison Miyamoto;Jean-Bernard Denault.
Developmental Biology (2001)
Processing of proendothelin-1 by human furin convertase
Jean-Bernard Denault;Audrey Claing;Pedro D'Orléans-Juste;Tatsuya Sawamura.
FEBS Letters (1995)
Characterization of proADAMTS5 processing by proprotein convertases.
Jean Michel Longpré;Daniel R. McCulloch;Bon Hun Koo;J. Preston Alexander.
The International Journal of Biochemistry & Cell Biology (2009)
Polyethylene Glycol Conjugation at Cys232 Prolongs the Half-Life of α1 Proteinase Inhibitor
André M. Cantin;Donald E. Woods;Diane Cloutier;Erick K. Dufour.
American Journal of Respiratory Cell and Molecular Biology (2002)
Inhibitory Potency and Specificity of Subtilase-like Pro-protein Convertase (SPC) Prodomains
Martin Fugère;Polizois C. Limperis;Véronique Beaulieu-Audy;Frédéric Gagnon.
Journal of Biological Chemistry (2002)
ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain.
Robert P T Somerville;Jean Michel Longpré;Elizabeth D. Apel;Renate M. Lewis.
Journal of Biological Chemistry (2004)
A Polyaromatic Caveolin-Binding-Like Motif in the Cytoplasmic Tail of the Type 1 Receptor for Angiotensin II Plays an Important Role in Receptor Trafficking and Signaling
Patrice C. Leclerc;Mannix Auger-Messier;Pascal M. Lanctot;Emanuel Escher.
Endocrinology (2002)
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