Richard Leduc

Overview

Best Publications

• Processing of transforming growth factor beta 1 precursor by human furin convertase.

  Claire M. Dubois;Marie-Hélène Laprise;François Blanchette;Larry E. Gentry

  612
  Citations

• KEX2-LIKE ENDOPROTEASES PC2 AND PC3 ACCURATELY CLEAVE A MODEL PROHORMONE IN MAMMALIAN CELLS : EVIDENCE FOR A COMMON CORE OF NEUROENDOCRINE PROCESSING ENZYMES

  Laurel Thomas;Richard Leduc;Barbara A. Thorne;Steven P. Smeekens

  424
  Citations

• Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.

  Robert P.T. Somerville;Jean-Michel Longpre;Katherine A. Jungers;J. Michael Engle

  399
  Citations

• Evidence that Furin Is an Authentic Transforming Growth Factor-β1-Converting Enzyme

  Claire M. Dubois;François Blanchette;Marie-Hélène Laprise;Richard Leduc

  327
  Citations

• A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

  Unknown

  319
  Citations

• Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage.

  R Leduc;S S Molloy;B A Thorne;G Thomas

  216
  Citations

• Subtilase-like pro-protein convertases: from molecular specificity to therapeutic applications.

  Unknown

  209
  Citations

• Characterization of METH-1/ADAMTS1 Processing Reveals Two Distinct Active Forms

  Juan Carlos Rodrı́guez-Manzaneque;Allison B. Milchanowski;Erick K. Dufour;Richard Leduc

  195
  Citations

• Ligand-Induced Signaling in the Absence of Furin Processing of Notch1

  Guy diSibio;Alison Miyamoto;Jean-Bernard Denault

  186
  Citations

• Processing of proendothelin-1 by human furin convertase

  Jean-Bernard Denault;Audrey Claing;Pedro D'Orléans-Juste;Tatsuya Sawamura

  170
  Citations

• Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors

  Yoon Namkung;Christian LeGouill;Sahil Kumar;Yubo Cao

  156
  Citations

• Characterization of proADAMTS5 processing by proprotein convertases.

  Jean Michel Longpré;Daniel R. McCulloch;Bon Hun Koo;J. Preston Alexander

  137
  Citations

• A Polyaromatic Caveolin-Binding-Like Motif in the Cytoplasmic Tail of the Type 1 Receptor for Angiotensin II Plays an Important Role in Receptor Trafficking and Signaling

  Patrice C. Leclerc;Mannix Auger-Messier;Pascal M. Lanctot;Emanuel Escher

  133
  Citations

• Polyethylene Glycol Conjugation at Cys232 Prolongs the Half-Life of α1 Proteinase Inhibitor

  André M. Cantin;Donald E. Woods;Diane Cloutier;Erick K. Dufour

  133
  Citations

• ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain.

  Robert P T Somerville;Jean Michel Longpré;Elizabeth D. Apel;Renate M. Lewis

  132
  Citations

• Inhibitory Potency and Specificity of Subtilase-like Pro-protein Convertase (SPC) Prodomains

  Martin Fugère;Polizois C. Limperis;Véronique Beaulieu-Audy;Frédéric Gagnon

  131
  Citations

• Discovery and Structure–Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions

  Alexandre Murza;Xavier Sainsily;David Coquerel;Jérôme Côté

  128
  Citations

• Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties

  Michel Demeule;Nicolas Beaudet;Anthony Régina;Élie Besserer-Offroy

  126
  Citations

• Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides.

  François Béliveau;Antoine Désilets;Richard Leduc

  125
  Citations

• The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptor is involved in mediating signal transduction but is not essential for internalization.

  S A Laporte;G Servant;D E Richard;E Escher

  113
  Citations

• The Peptidomimetic CXCR4 Antagonist TC14012 Recruits β-Arrestin to CXCR7 ROLES OF RECEPTOR DOMAINS

  Stéphanie Gravel;Camille Malouf;Philip E. Boulais;Yamina A. Berchiche

  103
  Citations

• Role of N-glycosylation in the expression and functional properties of human AT1 receptor.

  Pascal M. Lanctôt;Patrice C. Leclerc;Emanuel Escher;Richard Leduc

  102
  Citations