Suzanne Benjannet

Overview

Best Publications

• Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.

  Marianne Abifadel;Mathilde Varret;Jean-Pierre Rabès;Delphine Allard

  3453
  Citations

• Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

  Martin J Vincent;Eric Bergeron;Suzanne Benjannet;Bobbie R Erickson

  2120
  Citations

• The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation

  Nabil G. Seidah;Suzanne Benjannet;Louise Wickham;Jadwiga Marcinkiewicz

  1449
  Citations

• NARC-1/PCSK9 and Its Natural Mutants ZYMOGEN CLEAVAGE AND EFFECTS ON THE LOW DENSITY LIPOPROTEIN (LDL) RECEPTOR AND LDL CHOLESTEROL

  Suzanne Benjannet;David Rhainds;Rachid Essalmani;Janice Mayne

  772
  Citations

• PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.

  S Benjannet;N Rondeau;R Day;M Chrétien

  768
  Citations

• Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

  N. G. Seidah;M. Marcinkiewicz;S. Benjannet;L. Gaspar

  635
  Citations

• The Proprotein Convertase PCSK9 Induces the Degradation of Low Density Lipoprotein Receptor (LDLR) and Its Closest Family Members VLDLR and ApoER2

  Steve Poirier;Gaetan Mayer;Suzanne Benjannet;Eric Bergeron

  548
  Citations

• Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases

  Nabil G. Seidah;Suzanne Benjannet;Sangeeta Pareek;Michel Chrétien

  460
  Citations

• The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications.

  Suzanne Benjannet;David Rhainds;Josée Hamelin;Nasha Nassoury

  452
  Citations

• Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.

  Suzanne Benjannet;Aram Elagoz;Louise Wickham;Maya Mamarbachi

  443
  Citations

• Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.

  Nabil G. Seidah;Suzanne Benjannet;Sangeeta Pareek;Diane Savaria

  417
  Citations

• Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization

  Nabil G. Seidah;Seyed J. Mowla;Josée Hamelin;Aida M. Mamarbachi

  391
  Citations

• The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

  Geraldine Siegfried;Ajoy Basak;James A. Cromlish;Suzanne Benjannet

  300
  Citations

• The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR.

  Nasha Nassoury;Daniel A. Blasiole;Angie Tebon Oler;Suzanne Benjannet

  293
  Citations

• A new method for measurement of total plasma PCSK9: clinical applications.

  Geneviève Dubuc;Michel Tremblay;Guillaume Paré;Hélène Jacques

  274
  Citations

• Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2.

  S Benjannet;N Rondeau;L Paquet;A Boudreault

  244
  Citations

• From β-lipotropin to β-endorphin and 'pro-opio-melanocortin'

  M. Chrétien;S. Benjannet;F. Gossard;C. Gianoulakis

  207
  Citations

• Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1.

  S Benjannet;T Reudelhuber;C Mercure;N Rondeau

  193
  Citations

• The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1.

  Nabil G. Seidah;Suzanne Benjannet;Josée Hamelin;Aida M. Mamarbachi

  191
  Citations

• ZYMOGEN CLEAVAGE AND EFFECTS ON THE LOW DENSITY LIPOPROTEIN (LDL) RECEPTOR AND LDL CHOLESTEROL

  Suzanne Benjannet;David Rhainds;Rachid Essalmani;Janice Mayne

  2
  Citations