Donald F. Steiner

Research.com Recognitions

• 1988 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1975 - Member of the National Academy of Sciences

Overview

Best Publications

• The proprotein convertases.

  Donald F Steiner

  981
  Citations

• Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

  Jürgen K. Naggert;Lloyd D. Fricker;Oleg Varlamov;Patsy M. Nishina

  958
  Citations

• Insulin biosynthesis: evidence for a precursor.

  Donald F. Steiner;Dennis Cunningham;Lilian Spigelman;Bradley Aten

  895
  Citations

• Determination of Free and Total Insulin and C-Peptide in Insulin-treated Diabetics

  Hideshi Kuzuya;Petra M Blix;David L Horwitz;Donald F Steiner

  892
  Citations

• The new enzymology of precursor processing endoproteases

  D. F Steiner;S. P Smeekens;S Ohagi;Shu Jin Chan

  851
  Citations

• Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2.

  S P Smeekens;D F Steiner

  804
  Citations

• The biosynthesis of insulin and a probable precursor of insulin by a human islet cell adenoma.

  Donald F. Steiner;Philip E. Oyer

  777
  Citations

• Post-Translational Proteolysis in Polypeptide Hormone Biosynthesis

  Kevin Docherty;Donald F. Steiner

  753
  Citations

• The role of assembly in insulin's biosynthesis.

  Guy Dodson;Don Steiner

  709
  Citations

• Proteolytic processing in the secretory pathway.

  An Zhou;Gene Webb;Xiaorong Zhu;Donald F. Steiner

  675
  Citations

• Insulin gene mutations as a cause of permanent neonatal diabetes

  Julie Støy;Emma L. Edghill;Sarah E. Flanagan;Honggang Ye

  669
  Citations

• Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans.

  Steven P. Smeekens;Anthony S. Avruch;Joseph Lamendola;Shu Jin Chan

  614
  Citations

• Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2

  Machi Furuta;Hideki Yano;An Zhou;Yves Rouillé

  605
  Citations

• Processing mechanisms in the biosynthesis of proteins.

  Donald F. Steiner;Paul S. Quinn;Shu Jin Chan;Jon Marsh

  580
  Citations

• Binding and degradation of 125I-insulin by rat hepatocytes.

  S Terris;D F Steiner

  536
  Citations

• How insulin engages its primary binding site on the insulin receptor

  John G. Menting;Jonathan Whittaker;Mai B. Margetts;Linda J. Whittaker

  512
  Citations

• Insulin Mutation Screening in 1,044 Patients With Diabetes: Mutations in the INS Gene Are a Common Cause of Neonatal Diabetes but a Rare Cause of Diabetes Diagnosed in Childhood or Adulthood

  Emma L. Edghill;Sarah E. Flanagan;Ann-Marie Patch;Chris Boustred

  502
  Citations

• Proteolytic Processing Mechanisms in the Biosynthesis of Neuroendocrine Peptides: The Subtilisin-like Proprotein Convertases

  Yves Rouillé;Stephen J. Duguay;Kaare Lund;Machi Furuta

  498
  Citations

• Islet-cell-surface antibodies in juvenile diabetes mellitus.

  Åke Lernmark;Åke Lernmark;Zachary R. Freedman;Cecilia Hofmann;Arthur H. Rubenstein

  496
  Citations

• KEX2-LIKE ENDOPROTEASES PC2 AND PC3 ACCURATELY CLEAVE A MODEL PROHORMONE IN MAMMALIAN CELLS : EVIDENCE FOR A COMMON CORE OF NEUROENDOCRINE PROCESSING ENZYMES

  Laurel Thomas;Richard Leduc;Barbara A. Thorne;Steven P. Smeekens

  424
  Citations