Michael A. Weiss

Overview

Best Publications

• Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages.

  Stefan Linder;David Nelson;Michael Weiss;Martin Aepfelbacher

  534
  Citations

• How insulin engages its primary binding site on the insulin receptor

  John G. Menting;Jonathan Whittaker;Mai B. Margetts;Linda J. Whittaker

  512
  Citations

• Molecular basis of mammalian sexual determination: activation of Mullerian inhibiting substance gene expression by SRY

  Christopher M. Haqq;Chih Yen King;Etsuji Ukiyama;Sassan Falsafi

  351
  Citations

• Mechanism of insulin fibrillation: the structure of insulin under amyloidogenic conditions resembles a protein-folding intermediate

  Qing Xin Hua;Michael A Weiss

  341
  Citations

• Receptor binding redefined by a structural switch in a mutant human insulin.

  Qing Xin Hua;Qing Xin Hua;Steven E. Shoelson;Michel Kochoyan;Michel Kochoyan;Michael A. Weiss

  330
  Citations

• Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers

  Lingyang Zhu;Jill Wilken;Nelson B. Phillips;Umadevi Narendra

  242
  Citations

• Specific phosphopeptide binding regulates a conformational change in the PI 3-kinase SH2 domain associated with enzyme activation.

  Steven E. Shoelson;Mohanram Sivaraja;Kevin P. Williams;Patrick Hu

  208
  Citations

• Protective hinge in insulin opens to enable its receptor engagement.

  John G. Menting;Yanwu Yang;Shu Jin Chan;Nelson B. Phillips

  188
  Citations

• RNA recognition by arginine-rich peptide motifs.

  Michael A. Weiss;Narendra Narayana

  168
  Citations

• Structure of a protein in a kinetic trap.

  Qing Xin Hua;Shai N. Gozani;Ronald E. Chance;James A. Hoffmann

  161
  Citations

• Novel zinc finger motif in the basal transcriptional machinery: three-dimensional NMR studies of the nucleic acid binding domain of transcriptional elongation factor TFIIS.

  Xiuqi Qian;Shai N. Gozani;Ho Sup Yoon;Choon Ju Jeon

  158
  Citations

• Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.

  Qing Xin Hua;Shi Quan Hu;Bruce H. Frank;Wenhua Jia

  149
  Citations

• The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals.

  J M Backer;S E Shoelson;M A Weiss;Q X Hua

  145
  Citations

• Mutant INS-Gene Induced Diabetes of Youth: Proinsulin Cysteine Residues Impose Dominant-Negative Inhibition on Wild-Type Proinsulin Transport

  Ming Liu;Leena Haataja;Jordan Wright;Nalinda P. Wickramasinghe

  138
  Citations

• NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition

  Michael A. Weiss;Bruce H. Frank;Igor Khait;Allen Pekar

  138
  Citations

• Insulin assembly damps conformational fluctuations: Raman analysis of amide I linewidths in native states and fibrils.

  Jian Dong;Zhuli Wan;Maxim Popov;Paul R. Carey

  137
  Citations

• Glucose-responsive insulin by molecular and physical design

  Naveed A. Bakh;Abel B. Cortinas;Michael A. Weiss;Robert S. Langer

  137
  Citations

• Specificity of the PTB Domain of Shc for β Turn-forming Pentapeptide Motifs Amino-terminal to Phosphotyrosine

  Thomas Trüb;Wonjae E. Choi;Gert Wolf;Elizabeth Ottinger

  137
  Citations

• Two-dimensional 1H NMR study of the lambda operator site OL1: a sequential assignment strategy and its application

  Michael A. Weiss;Dinshaw J. Patel;Robert T. Sauer;Martin Karplus

  135
  Citations

• Higher-resolution structure of the human insulin receptor ectodomain: Multi-modal inclusion of the insert domain

  Tristan I. Croll;Brian J. Smith;Mai B. Margetts;Jonathan Whittaker

  132
  Citations