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Chemistry

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Overview

Stephen B. H. Kent is affiliated with the University of Chicago in the United States. Their research spans multiple fields, including biochemistry, genetics and molecular biology, medicine, and chemistry. Within these domains, the scientist's work covers subfields such as molecular biology, physical and theoretical chemistry, radiology, nuclear medicine and imaging, organic chemistry, and oncology.

The main topics of their research include chemical synthesis and analysis, monoclonal and polyclonal antibodies research, biochemical and structural characterization, peptidase inhibition and analysis, various chemistry research topics, advanced breast cancer therapies, and enzyme catalysis and immobilization.

Recent publications by Stephen B. H. Kent include:

  • A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth (2021, ACS Chemical Biology)
  • Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design (2020, ACS Omega)
  • Total synthesis of bovine pancreatic trypsin inhibitor and the protein diastereomer [Gly37D-Ala]BPTI using Boc chemistry solid phase peptide synthesis (2020, Peptide Science)
  • Fundamental Aspects of SPPS and Green Chemical Peptide Synthesis (2025, Journal of Peptide Science)
  • A Chemical Counterpart to the Resolution Step of Nature's Intein-Mediated Protein Splicing (2023, ACS Chemical Biology)

Stephen B. H. Kent has also contributed to book publications, including "Inventing Synthetic Methods to Discover How Enzymes Work" published in 2022 by GNT-Verlag GmbH eBooks.

Frequent collaborators in their research include Elkan Blout, Murray Goodman, Ephraim Katchalski, David N. Beratan, and Stephen C. Blacklow, each with multiple joint publications.

The scientist has published consistently in several venues, notable among them are Biopolymers, ACS Chemical Biology, Journal of Peptide Science, ACS Omega, and Peptide Science.

Best Publications

  • Synthesis of proteins by native chemical ligation

    Stephen B. H. Kent;Tom W. Muir;Philip E. Dawson

  • Fluorescence detection in automated DNA sequence analysis

    Lloyd M. Smith;Jane Z. Sanders;Robert J. Kaiser;Peter Hughes

  • Composite Quasar Spectra from the Sloan Digital Sky Survey

    Daniel E. Vanden Berk;Gordon T. Richards;Amanda Bauer;Michael A. Strauss

  • A cellular gene encodes scrapie PrP 27-30 protein

    Bruno Oesch;Bruno Oesch;David Westaway;Monika Wälchli;Monika Wälchli;Michael P. McKinley

  • Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis

    Ronald N. Zuckermann;Janice M. Kerr;Stephen B. H. Kent;Walter H. Moos

  • Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

    Alexander Wlodawer;Maria Miller;Mariusz Jaskólski;Bangalore K. Sathyanarayana

  • In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences.

    Martina SCHNölzer;Paul Alewood;Alun Jones;Dianne Alewood

  • Synthesis of native proteins by chemical ligation.

    Philip E. Dawson;Stephen B. H. Kent

  • Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction.

    Virender K. Sarin;Stephen B.H. Kent;James P. Tam;R.B. Merrifield

  • Spectroscopic Target Selection in the Sloan Digital Sky Survey: The Quasar Sample

    Gordon T. Richards;Xiaohui Fan;Heidi Jo Newberg;Michael A. Strauss

  • Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose

    Ruedi H. Aebersold;John Leavitt;Raul A. Saavedra;Leroy E. Hood

  • Total chemical synthesis of proteins

    Stephen B. H. Kent

  • Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution.

    Maria Miller;Jens Schneider;Bangalore K. Sathyanarayana;Mihaly V. Toth

  • The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

    Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson

  • Galaxy clustering in early sloan digital sky survey redshift data

    Idit Zehavi;Idit Zehavi;Michael R. Blanton;Michael R. Blanton;Joshua A. Frieman;Joshua A. Frieman;David H. Weinberg

  • Chemical synthesis of peptides and proteins.

    Stephen B. H. Kent

  • Identification and Chemical Synthesis of a Host Cell Receptor Binding Site on Hepatitis B Virus

    A.R. Neurath;S.B.H. Kent;N. Strick;K. Parker

  • Insights into the mechanism and catalysis of the native chemical ligation reaction.

    Erik C B Johnson;Stephen B H Kent

  • Purification and structural studies of a major scrapie prion protein

    Stanley B. Prusiner;Darlene F. Groth;David C. Bolton;Stephen B. Kent

  • The sloan digital sky survey-II supernova survey: technical summary

    Joshua A. Frieman;Joshua A. Frieman;Bruce Bassett;Andrew Becker;Changsu Choi

Frequent Co-Authors

Leroy Hood
Leroy Hood University of Washington
Philip E. Dawson
Philip E. Dawson Scripps Research Institute
Joshua A. Frieman
Joshua A. Frieman University of Chicago
Tom W. Muir
Tom W. Muir Princeton University
Brian T. Chait
Brian T. Chait Rockefeller University
James E. Gunn
James E. Gunn Princeton University
David J. Schlegel
David J. Schlegel Lawrence Berkeley National Laboratory
Daniel J. Eisenstein
Daniel J. Eisenstein Harvard University
István Csabai
István Csabai Eötvös Loránd University
Paul F. Alewood
Paul F. Alewood University of Queensland

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