Tom W. Muir

Research.com Recognitions

• 2020 - Fellow of the American Academy of Arts and Sciences
• 2013 - Fellow of the Royal Society of Edinburgh
• 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1999 - Fellow of Alfred P. Sloan Foundation

Overview

Best Publications

• Synthesis of proteins by native chemical ligation

  Stephen B. H. Kent;Tom W. Muir;Philip E. Dawson

  4999
  Citations

• Expressed protein ligation: A general method for protein engineering

  Tom W. Muir;Dolan Sondhi;Philip A. Cole

  1567
  Citations

• Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

  Peter W. Lewis;Manuel M. Müller;Matthew S. Koletsky;Francisco Cordero

  1395
  Citations

• How many human proteoforms are there

  Ruedi Aebersold;Jeffrey N. Agar;I. Jonathan Amster;Mark S. Baker

  1011
  Citations

• Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

  Johanna C. Scheuermann;Andrés Gaytán de Ayala Alonso;Katarzyna Oktaba;Nga Ly-Hartig

  920
  Citations

• Semisynthesis of Proteins by Expressed Protein Ligation

  Thomas William Muir

  878
  Citations

• RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.

  Jaehoon Kim;Mohamed Guermah;Robert K. McGinty;Jung Shin Lee

  626
  Citations

• Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence

  Patricia Mayville;Guangyong Ji;Ronald Beavis;Hongmei Yang

  625
  Citations

• Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

  Robert K. McGinty;Jaehoon Kim;Champak Chatterjee;Robert G. Roeder

  611
  Citations

• The TGF beta receptor activation process: an inhibitor- to substrate-binding switch.

  Morgan Huse;Tom W. Muir;Lan Xu;Ye Guang Chen

  532
  Citations

• Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

  Beat Fierz;Champak Chatterjee;Champak Chatterjee;Robert K McGinty;Maya Bar-Dagan

  501
  Citations

• Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3

  Lorna A. Farrelly;Robert E. Thompson;Shuai Zhao;Ashley E. Lepack

  461
  Citations

• Inteins: nature's gift to protein chemists

  Neel H. Shah;Tom W. Muir

  457
  Citations

• Protein ligation: an enabling technology for the biophysical analysis of proteins

  Vasant Muralidharan;Tom W Muir

  435
  Citations

• Crystal Structure of a Phosphorylated Smad2: Recognition of Phosphoserine by the MH2 Domain and Insights on Smad Function in TGF-β Signaling

  Jia-Wei Wu;Min Hu;Jijie Chai;Joan Seoane

  419
  Citations

• Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape

  Chao Lu;Siddhant U. Jain;Dominik Hoelper;Denise Bechet

  408
  Citations

• Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions

  Alexander J. Ruthenburg;Haitao Li;Thomas A. Milne;Scott Dewell

  397
  Citations

• The expanding landscape of ‘oncohistone’ mutations in human cancers

  Benjamin A. Nacev;Benjamin A. Nacev;Lijuan Feng;John D. Bagert;Agata E. Lemiesz

  385
  Citations

• Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC

  Gholson J. Lyon;Patricia Mayville;Tom W. Muir;Richard P. Novick

  371
  Citations

• Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus.

  S. Jarraud;G. J. Lyon;G. J. Lyon;A. M. S. Figueiredo;G. Lina

  369
  Citations