World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
30790
World Ranking
2680
National Ranking
60

Overview

Brian J. Smith is affiliated with the QIMR Berghofer Medical Research Institute in Australia. Their research spans multiple aspects of biochemistry, genetics, molecular biology, and medicine, with significant contributions to the understanding of molecular and cellular processes.

Their recent publications cover diverse topics and have appeared in respected scientific venues. Key papers include:

  • Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia, 2022, Intensive Care Medicine
  • A structurally minimized yet fully active insulin based on cone-snail venom insulin principles, 2020, Nature Structural & Molecular Biology
  • BAK core dimers bind lipids and can be bridged by them, 2020, Nature Structural & Molecular Biology
  • The functional evolution of architecturally different plant geranyl diphosphate synthases from geranylgeranyl diphosphate synthase, 2023, The Plant Cell
  • Predicting aqueous solubility by QSPR modeling, 2021, Journal of Molecular Graphics and Modelling

Their frequent co-authors include:

  • Nicholas A. Smith
  • Peter E. Czabotar
  • Peter M. Colman
  • Ruitao Jin
  • Sitong He

Brian J. Smith's work has been published repeatedly in the following venues:

  • UNC Libraries
  • Nature Structural & Molecular Biology
  • Journal of Biological Chemistry
  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Their main fields of study are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, the most significant subfields of study are:

  • Molecular Biology
  • Materials Chemistry
  • Biomedical Engineering
  • Surgery
  • Organic Chemistry

The primary research topics explored by Brian J. Smith include:

  • Ion channel regulation and function
  • Cell death mechanisms and regulation
  • Lipid Membrane Structure and Behavior
  • Signaling Pathways in Disease
  • RNA Interference and Gene Delivery
  • Pneumonia and Respiratory Infections
  • Nicotinic Acetylcholine Receptors Study

Best Publications

  • Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

    Lin Chen;Simon N. Willis;Andrew Wei;Brian J. Smith

  • Continuous positive airways pressure for obstructive sleep apnoea in adults

    Tammie L Giles;Toby J Lasserson;Brian Smith;John White

  • Heralded generation of ultrafast single photons in pure quantum states

    Peter James Mosley;Jeff S Lundeen;Brian J Smith;Piotr Wasylczyk;Piotr Wasylczyk

  • The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production.

    Jae Jin Chae;Geryl Wood;Seth L. Masters;Katharina Richard

  • BOA: AN R PACKAGE FOR MCMC OUTPUT CONVER-GENCE ASSESSMENT AND POSTERIOR INFERENCE

    Brian J. Smith

  • Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.

    Peter E. Czabotar;Peter E. Czabotar;Dana Westphal;Dana Westphal;Grant Dewson;Grant Dewson;Stephen Ma;Stephen Ma

  • A newly discovered protein export machine in malaria parasites

    Tania F de Koning-Ward;Tania F de Koning-Ward;Paul R. Gilson;Paul R. Gilson;Justin A Boddey;Melanie Rug

  • How insulin engages its primary binding site on the insulin receptor

    John G. Menting;Jonathan Whittaker;Mai B. Margetts;Linda J. Whittaker

  • Structural insights into the degradation of Mcl-1 induced by BH3 domains.

    Peter E. Czabotar;Erinna F. Lee;Mark F. van Delft;Catherine L. Day

  • ATTITUDES OF DOCTORS AND NURSES TOWARDS INCIDENT REPORTING: A QUALITATIVE ANALYSIS

    Marilyn J Kingston;Susan Margaret Evans;Brian J Smith;Jesia G Berry

  • Structure-guided design of a selective BCL-XL inhibitor

    Guillaume Lessene;Guillaume Lessene;Peter Edward Czabotar;Peter Edward Czabotar;Brad Sleebs;Brad Sleebs;Kerry Zobel

  • Non‐invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma

    Wei Jie Lim;Redhuan Mohammed Akram;Kristin V Carson;Satya Mysore

  • Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease

    Christian R Osadnik;Vanessa S Tee;Kristin V Carson-Chahhoud;Joanna Picot

  • An externally powered, multichannel, implantable stimulator-telemeter for control of paralyzed muscle

    B. Smith;Zhengnian Tang;M.W. Johnson;S. Pourmehdi

  • Factors associated with hospital admissions and repeat emergency department visits for adults with asthma

    Robert J Adams;Brian J Smith;Richard E Ruffin

  • Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family

    E F Lee;E F Lee;P E Czabotar;B J Smith;K Deshayes

  • Assigning absolute values to proton affinities: a differentiation between competing scales

    Brian J. Smith;Leo Radom

  • The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion.

    Lin Chen;Jeffrey J Gorman;Jenny McKimm-Breschkin;Lynne J Lawrence

  • Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity

    Zhi-Fu Tao;Lisa Hasvold;Le Wang;Xilu Wang

  • Transition structures for the interchange of hydrogen atoms within the water dimer

    Brian J. Smith;David J. Swanton;John A. Pople;Henry F. Schaefer

Frequent Co-Authors

Ian A. Walmsley
Ian A. Walmsley Imperial College London
Peter M. Colman
Peter M. Colman Walter and Eliza Hall Institute of Medical Research
Michael C. Lawrence
Michael C. Lawrence Walter and Eliza Hall Institute of Medical Research
Peter E. Czabotar
Peter E. Czabotar Walter and Eliza Hall Institute of Medical Research
Leo Radom
Leo Radom University of Sydney
Guillaume Lessene
Guillaume Lessene Walter and Eliza Hall Institute of Medical Research
Jonathan B. Baell
Jonathan B. Baell Monash University
John M. Buatti
John M. Buatti University of Iowa
W. Douglas Fairlie
W. Douglas Fairlie La Trobe University
Erinna F. Lee
Erinna F. Lee La Trobe University

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