D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 41 Citations 8,291 138 World Ranking 15698 National Ranking 470

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Organic chemistry

Jonathan B. Baell focuses on Biochemistry, Drug discovery, Pan-assay interference compounds, Pharmacology and Stereochemistry. His Biochemistry study combines topics in areas such as Sperm and Bioassay. His Drug discovery research incorporates themes from Combinatorial chemistry, Chemical biology, Histone acetyltransferase and Data science.

The Pan-assay interference compounds study combines topics in areas such as Natural product and Risk analysis. His research integrates issues of Apoptosis, Programmed cell death and In vitro, Structure–activity relationship in his study of Pharmacology. His In vitro study integrates concerns from other disciplines, such as Myeloid Cell Leukemia Sequence 1 Protein, Cancer, Cell culture, Cancer research and Bcl-xL.

His most cited work include:

  • New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays (1765 citations)
  • Chemistry: Chemical con artists foil drug discovery (584 citations)
  • The promise and peril of chemical probes. (443 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Biochemistry, Stereochemistry, Pharmacology, Structure–activity relationship and Combinatorial chemistry. Jonathan B. Baell combines topics linked to Trypanosoma brucei rhodesiense with his work on Biochemistry. His studies in Stereochemistry integrate themes in fields like Benzoylurea, Peptidomimetic, Chemical synthesis and Small molecule.

He usually deals with Pharmacology and limits it to topics linked to In vitro and Cell culture and Plasmodium falciparum. His Structure–activity relationship study deals with Haemonchus contortus intersecting with Cytotoxicity. Jonathan B. Baell has researched Drug discovery in several fields, including Computational biology, High-throughput screening and Data science.

He most often published in these fields:

  • Biochemistry (34.81%)
  • Stereochemistry (31.48%)
  • Pharmacology (21.11%)

What were the highlights of his more recent work (between 2019-2021)?

  • Drug discovery (17.78%)
  • Biochemistry (34.81%)
  • Catalysis (6.67%)

In recent papers he was focusing on the following fields of study:

Jonathan B. Baell mainly investigates Drug discovery, Biochemistry, Catalysis, IC50 and Combinatorial chemistry. His Drug discovery study combines topics from a wide range of disciplines, such as Chemical biology, Haemonchus contortus, Structure–activity relationship and High-content screening. His Biochemistry research is multidisciplinary, incorporating elements of Interleukin and Function.

His IC50 research incorporates elements of Bcl-xL, Benzoylurea, Small molecule and Bh3 mimetics. The Combinatorial chemistry study combines topics in areas such as In situ, Selectivity, Cycloaddition and Copper catalyzed. His research investigates the link between Cytotoxicity and topics such as African trypanosomiasis that cross with problems in In vitro.

Between 2019 and 2021, his most popular works were:

  • Metal-free C-C, C-O, C-S and C-N bond formation enabled by SBA-15 supported TFMSA (13 citations)
  • Metal-free C-C, C-O, C-S and C-N bond formation enabled by SBA-15 supported TFMSA (13 citations)
  • Catalytic O–H bond insertion reactions using surface modified sewage sludge as a catalyst (7 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • Organic chemistry

Catalysis, Interleukin, Enzyme, Function and Biochemistry are his primary areas of study. His work on Organic synthesis is typically connected to Functional group as part of general Catalysis study, connecting several disciplines of science. Interleukin is closely attributed to Glutathione transferase in his work.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Jonathan Bayldon Baell;Georgina A Holloway.
Journal of Medicinal Chemistry (2010)

2604 Citations

Chemistry: Chemical con artists foil drug discovery

Jonathan Bayldon Baell;Michael A Walters.
Nature (2014)

828 Citations

The promise and peril of chemical probes.

Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell.
Nature Chemical Biology (2015)

674 Citations

Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017-Utility and Limitations.

Jonathan B. Baell;Jonathan B. Baell;J. Willem M. Nissink.
ACS Chemical Biology (2018)

358 Citations

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

Ron O. Dror;Hillary F. Green;Celine Valant;David W. Borhani.
Nature (2013)

347 Citations

Structure-guided design of a selective BCL-XL inhibitor

Guillaume Lessene;Guillaume Lessene;Peter Edward Czabotar;Peter Edward Czabotar;Brad Sleebs;Brad Sleebs;Kerry Zobel.
Nature Chemical Biology (2013)

333 Citations

Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS).

Jonathan B. Baell.
Journal of Natural Products (2016)

306 Citations

FAF-Drugs3: a web server for compound property calculation and chemical library design

David Lagorce;Olivier Sperandio;Jonathan B. Baell;Maria A. Miteva.
Nucleic Acids Research (2015)

242 Citations

Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs.

Jonathan B. Baell;David C.S. Huang.
Biochemical Pharmacology (2002)

230 Citations

Assay Guidance Manual [Internet]

Sarine Markossian;Abigail Grossman;Kyle Brimacombe;Michelle Arkin.
(2004)

173 Citations

Editorial Boards

Future Medicinal Chemistry
(Impact Factor: 4.767)

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