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Jonathan B. Baell

Jonathan B. Baell

D-Index & Metrics

Chemistry

D-Index
49
Citations
14989
World Ranking
14631
National Ranking
324

Biology and Biochemistry

D-Index
54
Citations
15823
World Ranking
15395
National Ranking
422

Overview

Jonathan B. Baell is affiliated with Monash University in Australia and has contributed extensively to the fields of medicine, chemistry, and biochemistry, genetics, and molecular biology. Their research spans both core and interdisciplinary areas, reflecting a broad engagement with scientific problems.

The main fields of study for Baell include:

  • Medicine
  • Chemistry
  • Biochemistry, Genetics and Molecular Biology

Baell's work also delves into several subfields, such as:

  • Organic Chemistry
  • Molecular Biology
  • Materials Chemistry
  • Public Health, Environmental and Occupational Health
  • Epidemiology

Prominent topics covered in Baell's research include:

  • Catalytic C-H Functionalization Methods
  • Cyclopropane Reaction Mechanisms
  • Research on Leishmaniasis Studies
  • Trypanosoma species research and implications
  • Computational Drug Discovery Methods
  • Catalytic Cross-Coupling Reactions
  • Crystallization and Solubility Studies

Baell's publication record shows significant contributions to various scientific journals. Frequent publication venues are:

  • European Journal of Medicinal Chemistry
  • Journal of Medicinal Chemistry
  • RSC Medicinal Chemistry
  • The Cambridge Structural Database
  • The Journal of Organic Chemistry

Among Baell's recent papers are several works published between 2021 and 2023, including:

  • "Stimulus-cleavable chemistry in the field of controlled drug delivery" (2021, Chemical Society Reviews)
  • "Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers" (2021, Science Translational Medicine)
  • "Target 2035 - update on the quest for a probe for every protein" (2021, RSC Medicinal Chemistry)
  • "A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity" (2023, Nature Communications)
  • "Nuisance compounds in cellular assays" (2021, Cell chemical biology)

Baell collaborates frequently with a group of co-authors, which include:

  • Fei Huang
  • Yang Yu
  • Swapna Varghese
  • Jayme L. Dahlin
  • Xiangyan Yi

Best Publications

  • New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

    Jonathan Bayldon Baell;Georgina A Holloway

  • Chemistry: Chemical con artists foil drug discovery

    Jonathan Bayldon Baell;Michael A Walters

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017-Utility and Limitations.

    Jonathan B. Baell;Jonathan B. Baell;J. Willem M. Nissink

  • Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS).

    Jonathan B. Baell

  • Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

    Ron O. Dror;Hillary F. Green;Celine Valant;David W. Borhani

  • Structure-guided design of a selective BCL-XL inhibitor

    Guillaume Lessene;Guillaume Lessene;Peter Edward Czabotar;Peter Edward Czabotar;Brad Sleebs;Brad Sleebs;Kerry Zobel

  • FAF-Drugs3: a web server for compound property calculation and chemical library design

    David Lagorce;Olivier Sperandio;Jonathan B. Baell;Maria A. Miteva

  • Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

    Jonathan B. Baell;Jonathan B. Baell;David Leaver;Stefan J. Hermans;Gemma L. Kelly;Gemma L. Kelly

  • Assay Guidance Manual [Internet]

    Sarine Markossian;Abigail Grossman;Kyle Brimacombe;Michelle Arkin

  • Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs.

    Jonathan B. Baell;David C.S. Huang

  • Observations on screening-based research and some concerning trends in the literature

    Jonathan Bayldon Baell;Jonathan Bayldon Baell

  • HBO1 is required for the maintenance of leukaemia stem cells.

    Laura MacPherson;Laura MacPherson;Juliana Anokye;Miriam M. Yeung;Enid Y.N. Lam;Enid Y.N. Lam

  • Defining the mechanisms by which the reactive oxygen species by-product, 4-hydroxynonenal, affects human sperm cell function

    Mark A Baker;Anita S Weinberg;Louise Hetherington;Ana-Izabel Villaverde

  • Stimulus-cleavable chemistry in the field of controlled drug delivery

    Yufei Xue;Hua Bai;Bo Peng;Bin Fang

  • Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers.

    C Glenn Begley;Mark Ashton;Jonathan Baell;Michael Bettess

  • Low cost whole-organism screening of compounds for anthelmintic activity.

    Sarah Preston;Abdul Jabbar;Cameron J Nowell;Anja Joachim

  • KNIME Workflow to Assess PAINS Filters in SMARTS Format. Comparison of RDKit and Indigo Cheminformatics Libraries.

    Simon Saubern;Rajarshi Guha;Jonathan Bayldon Baell

  • The FAF-Drugs2 server

    David Lagorce;Julien Maupetit;Jonathan Baell;Olivier Sperandio

  • Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation

    Christopher P. Stanley;Ghassan J. Maghzal;Ghassan J. Maghzal;Anita Ayer;Anita Ayer;Jihan Talib;Jihan Talib

  • Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors.

    Jayme L. Dahlin;Kathryn M. Nelson;Jessica M. Strasser;Dalia Barsyte-Lovejoy

  • Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

    Melissa L Sykes;Jonathan Bayldon Baell;Jonathan Bayldon Baell;Jonathan Bayldon Baell;Marcel Kaiser;Marcel Kaiser;Eric Chatelain

Frequent Co-Authors

Guillaume Lessene
Guillaume Lessene Walter and Eliza Hall Institute of Medical Research
Vicky M. Avery
Vicky M. Avery Griffith University
Brian J. Smith
Brian J. Smith QIMR Berghofer Medical Research Institute
Peter E. Czabotar
Peter E. Czabotar Walter and Eliza Hall Institute of Medical Research
Peter M. Colman
Peter M. Colman Walter and Eliza Hall Institute of Medical Research
Andreas Hofmann
Andreas Hofmann University of Melbourne
Robin B. Gasser
Robin B. Gasser University of Melbourne
Marcel Kaiser
Marcel Kaiser Swiss Tropical and Public Health Institute
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research

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