What is he best known for?
The fields of study he is best known for:
- Enzyme
- Gene
- Internal medicine
His primary areas of investigation include Pharmacology, Hepatocyte, Biochemistry, Cell culture and In vivo.
His research integrates issues of Cytochrome P450 and Enzyme inducer in his study of Pharmacology.
Albert P. Li has researched Hepatocyte in several fields, including Membrane transport, Perfusion, Andrology, Liver cytology and Metabolism.
His study explores the link between Biochemistry and topics such as Molecular biology that cross with problems in Phosphoribosyl transferase and Chinese hamster ovary cell.
His Cell culture study combines topics in areas such as Cancer research, In vitro toxicology, Cancer cell, Endoplasmic reticulum and Cuboidal Cell.
His work in In vivo addresses subjects such as In vitro, which are connected to disciplines such as Clinical trial.
His most cited work include:
- Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies (590 citations)
- Screening for human ADME/Tox drug properties in drug discovery (341 citations)
- Substrates of human hepatic cytochrome P450 3A4 (321 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Pharmacology, Biochemistry, Cell culture, In vitro and Drug metabolism.
His Pharmacology research is multidisciplinary, relying on both Toxicity and Cytochrome P450.
The Cytochrome P450 study combines topics in areas such as Isozyme and Enzyme inducer.
The concepts of his Cell culture study are interwoven with issues in Cell and Cell biology.
In his work, Computational biology and Sulfation is strongly intertwined with In vivo, which is a subfield of In vitro.
His study in Drug metabolism is interdisciplinary in nature, drawing from both Intestinal mucosa, Cryopreservation and CYP2A6.
He most often published in these fields:
- Pharmacology (35.65%)
- Biochemistry (31.30%)
- Cell culture (21.30%)
What were the highlights of his more recent work (between 2015-2021)?
- Pharmacology (35.65%)
- Drug metabolism (16.52%)
- Biochemistry (31.30%)
In recent papers he was focusing on the following fields of study:
Albert P. Li mainly focuses on Pharmacology, Drug metabolism, Biochemistry, In vitro and Cryopreservation.
His work carried out in the field of Pharmacology brings together such families of science as CYP3A, Drug metabolizing enzymes and Metabolism.
His Drug metabolism research integrates issues from CYP3A4, Enterocyte, In vitro system and Intestinal mucosa.
His research in the fields of Glucuronidation, Microsome, CYP1A2 and Detoxification overlaps with other disciplines such as Throughput.
His studies in In vitro integrate themes in fields like Transporter, Chromatography, Bioassay, Biotransformation and In vivo.
His In vivo study incorporates themes from Cell culture, Pharmacokinetics, Free fraction and Hepatocyte.
Between 2015 and 2021, his most popular works were:
- Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations (43 citations)
- Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors. (28 citations)
- Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles (26 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Internal medicine
His primary areas of study are Pharmacology, Biochemistry, In vivo, In vitro and CYP3A4.
A large part of his Pharmacology studies is devoted to Drug.
His biological study spans a wide range of topics, including Ileum, Jejunum, Cytochrome P450 and Hepatocyte.
Albert P. Li has researched Hepatocyte in several fields, including Unfolded protein response, Endoplasmic reticulum and Salubrinal.
Pharmacokinetics, Metabolism and Metabolite is closely connected to Transporter in his research, which is encompassed under the umbrella topic of In vitro.
His CYP3A4 study integrates concerns from other disciplines, such as Intestinal mucosa and Drug metabolism.
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