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José V. Castell

José V. Castell

University of Valencia
Spain

Award Badge
Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
26002
World Ranking
3853
National Ranking
45

José V. Castell publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where José V. Castell sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 323 publications — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

José V. Castell D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where José V. Castell sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 81 D-Index — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

José V. Castell is affiliated with the University of Valencia in Spain. Their research spans multiple fields with a focus on Medicine and Biochemistry, Genetics and Molecular Biology. They have made contributions in several key subfields, including Molecular Biology, Pharmacology, Hepatology, Epidemiology, and Surgery.

Their scholarly work concentrates on thematic areas such as Drug-Induced Hepatotoxicity and Protection, Metabolomics and Mass Spectrometry Studies, Liver Disease Diagnosis and Treatment, Pharmacogenetics and Drug Metabolism, Liver physiology and pathology, Organ Transplantation Techniques and Outcomes, and Drug Transport and Resistance Mechanisms.

José V. Castell has frequently published in these venues:

  • Archives of Toxicology
  • Toxicology Letters
  • Zenodo (CERN European Organization for Nuclear Research)
  • Toxicology
  • International Journal of Molecular Sciences

Frequent collaborators in their research include:

  • Marta Moreno-Torres
  • Alfonso Quintás-Cardama
  • Ramiro Jover
  • Eugenia Pareja
  • Erika Moro

Among their recent publications are:

  • Comparing in vitro human liver models to in vivo human liver using RNA-Seq, 2020, Archives of Toxicology
  • Safer chemicals using less animals: kick-off of the European ONTOX project, 2021, Toxicology
  • Comparing Targeted vs. Untargeted MS2 Data-Dependent Acquisition for Peak Annotation in LC-MS Metabolomics, 2020, Metabolites
  • Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes, 2021, Archives of Toxicology
  • The Vitamin D Receptor Regulates Glycerolipid and Phospholipid Metabolism in Human Hepatocytes, 2020, Biomolecules

Best Publications

  • Interleukin-6 and the acute phase response

    P C Heinrich;J V Castell;T Andus

  • Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes

    José V. Castell;Maria J. Gómez-Lechón;Martina David;Tilo Andus

  • Acute-phase response of human hepatocytes: regulation of acute-phase protein synthesis by interleukin-6.

    José V. Castell;Maria José Gómez-lechón;Martina David;Ricardo Fabra

  • Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes.

    José V. Castell;Maria J. Gómez-Lechón;Martina David;Toshio Hirano

  • A human hepatocellular in vitro model to investigate steatosis.

    María José Gómez-Lechón;María Teresa Donato;Alicia Martínez-Romero;Nuria Jiménez

  • Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells.

    C. Rodríguez-Antona;M. T. Donato;A. Boobis;R. J. Edwards

  • Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat.

    José V. Castell;Thomas Geiger;Volker Gross;Tilo Andus

  • Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells

    Raquel Taléns-Visconti;Ana Bonora;Ramiro Jover;Vicente Mirabet

  • Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach

    José V. Castell;M. Teresa Donato;María José Gómez-Lechón

  • Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways

    Roque Bort;Katherine Macé;Alan Boobis;Marı́a-José Gómez-Lechón

  • Human hepatocytes in primary culture: the choice to investigate drug metabolism in man.

    M. J. Gomez-Lechon;M. T. Donato;J. V. Castell;R. Jover

  • FLUORESCENCE-BASED ASSAYS FOR SCREENING NINE CYTOCHROME P450 (P450) ACTIVITIES IN INTACT CELLS EXPRESSING INDIVIDUAL HUMAN P450 ENZYMES

    M. Teresa Donato;Nuria Jiménez;José V. Castell;M. José Gómez-Lechón

  • Human hepatocytes as a tool for studying toxicity and drug metabolism.

    M. J. Gomez-Lechon;M. T. Donato;J. V. Castell;R. Jover

  • Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting.

    Ramiro Jover;Roque Bort;María J. Gómez‐Lechón;José V. Castell

  • Interleukin-6. The major regulator of acute-phase protein synthesis in man and rat.

    JOSé V. Castell;Tilo Andus;Dieter Kunz;Peter C. Heinrich

  • Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

    Juan C. García-Cañaveras;M. Teresa Donato;José V. Castell;Agustín Lahoz

  • Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.

    José V Castell;Ramiro Jover;Celia P Martínez-Jiménez;María José Gómez-Lechón

  • Down-regulation of human CYP3A4 by the inflammatory signal interleukin 6: molecular mechanism and transcription factors involved

    Ramiro Jover;Roque Bort;Ma. José Gómez-Lechón;Joseé V. Castell

  • Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London.

    Juliana Puppi;Stephen C. Strom;Robin D. Hughes;Sanjay Bansal

  • Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

    M.José Gómez-Lechón;Xavier Ponsoda;Enrique O’Connor;Teresa Donato

Frequent Co-Authors

Ramiro Jover
Ramiro Jover University of Valencia
Miguel A. Miranda
Miguel A. Miranda Universitat Politècnica de València
Jos C. S. Kleinjans
Jos C. S. Kleinjans Maastricht University
José-Enrique O'Connor
José-Enrique O'Connor University of Valencia
Peter C. Heinrich
Peter C. Heinrich University of Freiburg
Vera Rogiers
Vera Rogiers Vrije Universiteit Brussel
Magnus Ingelman-Sundberg
Magnus Ingelman-Sundberg Karolinska Institute
André Guillouzo
André Guillouzo University of Rennes
Ralf Herwig
Ralf Herwig Max Planck Society
Joost H.M. van Delft
Joost H.M. van Delft Maastricht University

External Links

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Best Scientists Citing José V. Castell

Miguel A. Miranda

Miguel A. Miranda

Universitat Politècnica de València

Publications: 71

Vera Rogiers

Vera Rogiers

Vrije Universiteit Brussel

Publications: 46

Mathieu Vinken

Mathieu Vinken

Vrije Universiteit Brussel

Publications: 41

Ramiro Jover

Ramiro Jover

University of Valencia

Publications: 33

Olavi Pelkonen

Olavi Pelkonen

University of Oulu

Publications: 32

Thomas Hartung

Thomas Hartung

Johns Hopkins University

Publications: 30

Edward L. LeCluyse

Edward L. LeCluyse

Research Triangle Park Foundation

Publications: 29

Stephen C. Strom

Stephen C. Strom

Karolinska Institute

Publications: 28

Tommy B. Andersson

Tommy B. Andersson

AstraZeneca (United Kingdom)

Publications: 26

Tsuyoshi Yokoi

Tsuyoshi Yokoi

Nagoya University

Publications: 25

André Guillouzo

André Guillouzo

University of Rennes

Publications: 24

Jos C. S. Kleinjans

Jos C. S. Kleinjans

Maastricht University

Publications: 24

Magnus Ingelman-Sundberg

Magnus Ingelman-Sundberg

Karolinska Institute

Publications: 23

Martin L. Yarmush

Martin L. Yarmush

Rutgers, The State University of New Jersey

Publications: 23

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Jan G. Hengstler

TU Dortmund University

Publications: 21

Edward T. Morgan

Edward T. Morgan

Emory University

Publications: 21

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