Ramiro Jover

Overview

Best Publications

• Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

  David Porras;Esther Nistal;Susana Martínez-Flórez;Sandra Pisonero-Vaquero

  493
  Citations

• Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells

  Raquel Taléns-Visconti;Ana Bonora;Ramiro Jover;Vicente Mirabet

  345
  Citations

• Diclofenac Toxicity to Hepatocytes: A Role for Drug Metabolism in Cell Toxicity

  R Bort;X Ponsoda;R Jover;M J Gómez-Lechón

  337
  Citations

• Human hepatocytes in primary culture: the choice to investigate drug metabolism in man.

  M. J. Gomez-Lechon;M. T. Donato;J. V. Castell;R. Jover

  298
  Citations

• Human hepatocytes as a tool for studying toxicity and drug metabolism.

  M. J. Gomez-Lechon;M. T. Donato;J. V. Castell;R. Jover

  282
  Citations

• Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting.

  Ramiro Jover;Roque Bort;María J. Gómez‐Lechón;José V. Castell

  277
  Citations

• Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells.

  S Carbajo-Pescador;R Ordoñez;M Benet;R Jover

  276
  Citations

• Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.

  José V Castell;Ramiro Jover;Celia P Martínez-Jiménez;María José Gómez-Lechón

  261
  Citations

• Down-regulation of human CYP3A4 by the inflammatory signal interleukin 6: molecular mechanism and transcription factors involved

  Ramiro Jover;Roque Bort;Ma. José Gómez-Lechón;Joseé V. Castell

  260
  Citations

• Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

  M.José Gómez-Lechón;Xavier Ponsoda;Enrique O’Connor;Teresa Donato

  223
  Citations

• Hepatic Cytochrome P450 Down-regulation During Aseptic Inflammation in the Mouse Is Interleukin 6 Dependent

  Elmar Siewert;Roque Bort;Reinhart Kluge;Peter C. Heinrich

  213
  Citations

• Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix.

  Maria José Gómez‐Lechón;Ramiro Jover;Teresa Donato;Xavier Ponsoda

  189
  Citations

• Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells

  Ramiro Jover;Roque Bort;M.José Gómez-Lechón;José V Castell

  172
  Citations

• Transcriptional Regulation and Expression of CYP3A4 in Hepatocytes

  Celia P. Martinez-Jimenez;Ramiro Jover;M. Teresa Donato;Jose V. Castell

  170
  Citations

• Human mesenchymal stem cells from adipose tissue: Differentiation into hepatic lineage.

  R. Taléns-Visconti;A. Bonora;R. Jover;V. Mirabet

  144
  Citations

• Transcriptional Regulation of Human CYP3A4 Basal Expression by CCAAT Enhancer-Binding Protein α and Hepatocyte Nuclear Factor-3γ

  C. Rodrı́guez-Antona;R. Bort;R. Jover;N. Tindberg

  140
  Citations

• Cytotoxicity Evaluation of the First Ten MEIC Chemicals: Acute Lethal Toxicity in Man Predicted by Cytotoxicity in Five Cellular Assays and by Oral LD50 Tests in Rodents:

  Björn Ekwall;Inger Bondesson;José V. Castell;Maria José Gómez-Lechón

  137
  Citations

• Quantitative RT-PCR measurement of human cytochrome P-450s: application to drug induction studies.

  Cristina Rodríguez-Antona;Ramiro Jover;Maria-José Gómez-Lechón;José V. Castell

  128
  Citations

• Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease.

  Sandra Pisonero-Vaquero;Ángel Martínez-Ferreras;María Victoria García-Mediavilla;María Victoria García-Mediavilla;Susana Martínez-Flórez

  120
  Citations

• Foxa1 Reduces Lipid Accumulation in Human Hepatocytes and Is Down-Regulated in Nonalcoholic Fatty Liver

  Marta Moya;Marta Benet;Carla Guzmán;Laia Tolosa

  118
  Citations