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José A. G. Agúndez

José A. G. Agúndez

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
13744
World Ranking
9237
National Ranking
167

Overview

José A. G. Agúndez is affiliated with the Instituto de Salud Carlos III in Spain. Their research spans multiple disciplines within medicine, with a notable focus on neurology and pharmacology. Their work also touches on molecular biology, epidemiology, and physiology, reflecting a broad engagement with biomedical sciences.

Their scientific contributions are concentrated on specific topics that include:

  • Parkinson's Disease Mechanisms and Treatments
  • Pharmacogenetics and Drug Metabolism
  • Neurological disorders and treatments
  • Restless Legs Syndrome Research
  • Sleep and Wakefulness Research
  • Inflammatory mediators and NSAID effects
  • Glycogen Storage Diseases and Myoclonus

José A. G. Agúndez has published research papers in prominent venues. Frequently publishing work appears in:

  • Frontiers in Pharmacology
  • Clinical Pharmacology & Therapeutics
  • Journal of Personalized Medicine
  • International Journal of Molecular Sciences
  • European Journal of Neurology

Some recent publications by José A. G. Agúndez include:

  • Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti-Inflammatory Drugs, 2020, Clinical Pharmacology & Therapeutics
  • Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review, 2021, European Journal of Pharmaceutical Sciences
  • PharmVar GeneFocus: CYP2C19, 2020, Clinical Pharmacology & Therapeutics
  • PharmVar GeneFocus: CYP2C9, 2021, Clinical Pharmacology & Therapeutics
  • Cerebrospinal and blood levels of amino acids as potential biomarkers for Parkinson's disease: review and meta-analysis, 2020, European Journal of Neurology

José A. G. Agúndez's body of work includes collaborations with several frequent co-authors, illustrating a network of research partnerships. These collaborators include:

  • Elena García-Martín
  • Félix Javier Jiménez-Jiménez
  • Hortensia Alonso-Navarro
  • Ignacio Álvarez
  • Pau Pástor

In addition to journal articles, José A. G. Agúndez has contributed to book publications, including a title published by Frontiers Media titled Insights in Pharmacogenetics and Pharmacogenomics: 2021 in 2022.

Their main fields of study are primarily within medicine, supported by 121 publications. Subfields show a diverse focus including neurology, pharmacology, molecular biology, epidemiology, and physiology, reflecting an integrated approach to understanding complex biomedical topics.

Best Publications

  • A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

    Ian P.M. Tomlinson;Emily Webb;Luis Carvajal-Carmona;Peter Broderick

  • Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process

    Kelly E. Caudle;Teri E. Klein;James M. Hoffman;Daniel J. Muller

  • Cytochrome P450 gene polymorphism and cancer.

    Jose A G Agundez

  • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C19 and Voriconazole Therapy.

    B. Moriyama;A. Owusu Obeng;A. Owusu Obeng;J. Barbarino;Scott Robert Penzak

  • Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti-Inflammatory Drugs.

    Katherine N. Theken;Craig R. Lee;Li Gong;Kelly E. Caudle

  • Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population

    José A. G. Agúndez;José A. G. Agúndez;María C. Ledesma;María C. Ledesma;José M. Ladero;José M. Ladero;Julio Benítez;Julio Benítez

  • Characteristics of subjects experiencing hypersensitivity to non-steroidal anti-inflammatory drugs: patterns of response.

    I. Doña;N. Blanca-López;J. A. Cornejo-García;M. J. Torres

  • Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.

    Mikael Oscarson;Roman A. McLellan;Harriet Gullstén;José A.G. Agúndez

  • Glutathione S-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury.

    M. Isabel Lucena;Raúl J. Andrade;Carmen Martínez;Eugenia Ulzurrun

  • Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms.

    Elena García‐Martín;Carmen Martínez;Beatriz Tabarés;Jesús Frías

  • Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review.

    Zahari Vinarov;Mohammad Abdallah;José A.G. Agundez;Karel Allegaert

  • Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron.

    G. C. Bell;K. E. Caudle;M. Whirl-Carrillo;R. J. Gordon

  • Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2-receptor antagonists.

    Carmen Martínez;Carlos Albet;José A.G. Agúndez;Eduardo Herrero

  • Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals.

    Elena García-Martín;Carmen Martínez;José M. Ladero;José A. G. Agúndez

  • Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use.

    Carmen Martínez;Gerardo Blanco;José M Ladero;Elena García-Martín

  • CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity.

    Elena García‐Martín;Elena García‐Martín;Elena García‐Martín;Carmen Martínez;Carmen Martínez;Carmen Martínez;Rosa M. Pizarro;Rosa M. Pizarro;Rosa M. Pizarro;Francisco J. García‐Gamito;Francisco J. García‐Gamito;Francisco J. García‐Gamito

  • The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)‐ibuprofen enantiomer in healthy subjects

    Carmen Martínez;Elena García-Martín;Gerardo Blanco;Francisco J G Gamito

  • Polymorphisms of human N-acetyltransferases and cancer risk.

    José A G Agúndez

  • Mitochondrial Superoxide Dismutase and Glutathione Peroxidase in Idiosyncratic Drug-Induced Liver Injury

    M. Isabel Lucena;Elena García-Martín;Raúl J. Andrade;Carmen Martínez

  • Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting

    Lisa V. Kalman;José A.G. Agúndez;Malin Lindqvist Appell;Gillian C. Bell

Frequent Co-Authors

Félix Javier Jiménez-Jiménez
Félix Javier Jiménez-Jiménez Hospital Universitario del Sureste
Pau Pastor
Pau Pastor University of Navarra
Carmen Martinez Mora
Carmen Martinez Mora Complutense University of Madrid
Miguel Blanca
Miguel Blanca Hospital Universitario Infanta Leonor
Maria J. Torres
Maria J. Torres Hospital Universitario La Paz
Paloma Campo
Paloma Campo Instituto de Salud Carlos III
Hannu Raunio
Hannu Raunio University of Eastern Finland
Cristobalina Mayorga
Cristobalina Mayorga University of Malaga
Teri E. Klein
Teri E. Klein Stanford University
Andrea Gaedigk
Andrea Gaedigk University of Missouri–Kansas City

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