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Molecular Biology

D-Index
54
Citations
12077
World Ranking
2315
National Ranking
154

Overview

Thorsten Stiewe is affiliated with Philipp University of Marburg in Germany. Their research contributions span several interconnected fields in biology and medicine, with a particular focus on cancer and molecular biology.

The primary fields of study for Thorsten Stiewe include Biochemistry, Genetics and Molecular Biology, and Medicine. More specific subfields that define their work are Molecular Biology, Oncology, Cancer Research, Immunology, and Epidemiology.

Their research covers multiple main topics such as Epigenetics and DNA Methylation, RNA modifications and cancer, Cancer-related Molecular Pathways, Cancer Genomics and Diagnostics, Genomics and Chromatin Dynamics, RNA Research and Splicing, and Cancer-related gene regulation.

Frequent publication venues for Stiewe's work illustrate a broad engagement with scientific communities focused on cancer and molecular biology. Key journals include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Cancer Research
  • Nucleic Acids Research
  • Nature Communications

Some recent papers provide insight into the scientist's research directions and focus areas. These include:

  • "The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic" (2020, Nature)
  • "Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer" (2020, Science Advances)
  • "mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability" (2020, Nature Communications)
  • "Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells" (2022, EMBO Reports)
  • "p53's Extended Reach: The Mutant p53 Secretome" (2020, Biomolecules)

The frequent co-authors collaborating with Thorsten Stiewe are:

  • Andrea Nist
  • Marco Mernberger
  • Florian Finkernagel
  • Michael Wanzel
  • Robert Liefke

Best Publications

  • SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells.

    Parysatis Sachs;Dong Ding;Philipp Bergmaier;Boris Lamp

  • Role of the p53-homologue p73 in E2F1-induced apoptosis.

    Thorsten Stiewe;Brigitte M. Pützer

  • The p53 family in differentiation and tumorigenesis.

    Thorsten Stiewe

  • The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

    Maik Luu;Sabine Pautz;Sabine Pautz;Vanessa Kohl;Rajeev Singh

  • The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

    Eliran Kadosh;Irit Snir-Alkalay;Avanthika Venkatachalam;Shahaf May

  • Transactivation-deficient ΔTA-p73 Inhibits p53 by Direct Competition for DNA Binding IMPLICATIONS FOR TUMORIGENESIS

    Thorsten Stiewe;Carmen C. Theseling;Brigitte M. Pützer

  • Transactivation-deficient ΔTA-p73 Acts as an Oncogene

    Thorsten Stiewe;Sonja Zimmermann;Andreja Frilling;Helmut Esche

  • Gene expression changes in response to E2F1 activation

    Jens Stanelle;Thorsten Stiewe;Carmen C. Theseling;Martin Peter

  • A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism

    Ariel Pribluda;Ela Elyada;Zoltan Wiener;Haya Hamza

  • Role of p73 in malignancy: tumor suppressor or oncogene?

    T Stiewe;B M Pützer

  • Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

    M Michaelis;F Rothweiler;S Barth;J Cinatl

  • Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma

    Gamal-André Banat;Aleksandra Tretyn;Soni Savai Pullamsetti;Jochen Wilhelm

  • p53 family members in myogenic differentiation and rhabdomyosarcoma development.

    Hakan Cam;Heidi Griesmann;Michaela Beitzinger;Lars Hofmann

  • Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer

    Poonam Sarode;Xiang Zheng;Georgia A. Giotopoulou;Andreas Weigert

  • Quantitative TP73 Transcript Analysis in Hepatocellular Carcinomas

    Thorsten Stiewe;Sebastian Tuve;Martin Peter;Andrea Tannapfel

  • DNA Binding Cooperativity of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis

    Katharina Schlereth;Rasa Beinoraviciute-Kellner;Marie K. Zeitlinger;Anne C. Bretz

  • mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability

    Niklas Gremke;Pierfrancesco Polo;Aaron Dort;Jean Schneikert

  • How mutations shape p53 interactions with the genome to promote tumorigenesis and drug resistance.

    Thorsten Stiewe;Tali E. Haran

  • MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6

    Bastian Stielow;Florian Finkernagel;Thorsten Stiewe;Andrea Nist

  • A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome

    Silke Reinartz;Florian Finkernagel;Till Adhikary;Verena Rohnalter

Frequent Co-Authors

Rolf Müller
Rolf Müller Saarland University
Werner Seeger
Werner Seeger University of Giessen
Andreas Rosenwald
Andreas Rosenwald University of Würzburg
Martin Michaelis
Martin Michaelis University of Kent
Yinon Ben-Neriah
Yinon Ben-Neriah Hebrew University of Jerusalem
Michael Kracht
Michael Kracht University of Giessen
Klaus Schughart
Klaus Schughart Helmholtz Centre for Infection Research
Markus Sauer
Markus Sauer University of Würzburg
Jindrich Cinatl
Jindrich Cinatl Goethe University Frankfurt
Achim D. Gruber
Achim D. Gruber Freie Universität Berlin

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