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Biology and Biochemistry

D-Index
67
Citations
13224
World Ranking
8361
National Ranking
650

Overview

Martin Michaelis is affiliated with the University of Kent in the United Kingdom. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to molecular biology, infectious diseases, surgery, oncology, and pulmonary and respiratory medicine.

The scientist's work addresses several main topics, including:

  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Neuroblastoma Research and Treatments
  • Cancer therapeutics and mechanisms
  • Genital Health and Disease
  • Prostate Cancer Treatment and Research
  • Cell death mechanisms and regulation

Michaelis has a body of recent publications demonstrating involvement in cancer research, viral infections, and immunology. Notable papers include:

  • Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction (2020, Cells)
  • Botanical drugs and supplements affecting the immune response in the time of COVID-19: Implications for research and clinical practice (2020, Phytotherapy Research)
  • Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy (2021, Cancer Discovery)
  • Aprotinin Inhibits SARS-CoV-2 Replication (2020, Cells)
  • SARS-CoV-2 and SARS-CoV differ in their cell tropism and drug sensitivity profiles (2020, bioRxiv [Cold Spring Harbor Laboratory])

The scientist publishes frequently in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Cells
  • Journal of Medical Virology
  • The Journal of Urology

Michaelis collaborates often with several coauthors, including:

  • Jindřich Činátl
  • Mark N. Wass
  • Florian Rothweiler
  • Denisa Bojková
  • Sandra Ciesek

Best Publications

  • Antiviral Activity of Glycyrrhizic Acid Derivatives against SARS−Coronavirus

    Gerold Hoever;Lidia Baltina;Martin Michaelis;Rimma Kondratenko

  • Covalent Linkage of Apolipoprotein E to Albumin Nanoparticles Strongly Enhances Drug Transport into the Brain

    Kerstin Michaelis;Michael M Hoffmann;Sebastian Dreis;Elisabeth Herbert

  • The Story of Human Cytomegalovirus and Cancer: Increasing Evidence and Open Questions

    Martin Michaelis;Hans Wilhelm Doerr;Jindrich Cinatl

  • Preparation, characterisation and maintenance of drug efficacy of doxorubicin-loaded human serum albumin (HSA) nanoparticles

    S Dreis;Florian Rothweiler;Martin Michaelis;Jindrich Cinatl

  • Valproic acid inhibits angiogenesis in vitro and in vivo.

    Martin Michaelis;U. Ruth Michaelis;Ingrid Fleming;Tatyana Suhan

  • Ribavirin and interferon-β synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines

    Birgit Morgenstern;Martin Michaelis;Patrick C Baer;Hans Wilhelm Doerr

  • Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies.

    Roman A. Blaheta;Martin Michaelis;Pablo Hernáiz Driever;Jindrich Cinatl

  • N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus.

    Janina Geiler;Martin Michaelis;Patrizia Naczk;Anke Leutz

  • Enhanced drug targeting by attachment of an anti αv integrin antibody to doxorubicin loaded human serum albumin nanoparticles

    Sylvia Wagner;Florian Rothweiler;Marion G. Anhorn;Daniel Sauer

  • Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin A and baicalein in H5N1 influenza A virus-infected cells.

    Patchima Sithisarn;Martin Michaelis;Manfred Schubert-Zsilavecz;Jindrich Cinatl

  • Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

    M Michaelis;F Rothweiler;S Barth;J Cinatl

  • Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats.

    Irmgard Tegeder;Ellen Niederberger;Ronald Schmidt;Susanne Kunz

  • Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression

    Martin Michaelis;Janina Geiler;Patrizia Naczk;Patchima Sithisarn

  • Toona sinensis Roem tender leaf extract inhibits SARS coronavirus replication.

    Chung Jen Chen;Martin Michaelis;Hseng Kuang Hsu;Chin Chuan Tsai

  • SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

    Constanze Schneider;Thomas Oellerich;Hanna-Mari Baldauf;Hanna-Mari Baldauf;Sarah-Marie Schwarz

  • Valproic acid as anti-cancer drug

    Martin Michaelis;Hans Wilhelm Doerr;Jindrich Cinatl

  • Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G2/M cell cycle arrest.

    Navin Sarin;Florian Engel;Ganna V. Kalayda;Mareike Mannewitz

  • Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.

    Tom Van Maerken;Liesbeth Ferdinande;Jasmien Taildeman;Irina Lambertz

  • Novel swine-origin influenza A virus in humans: another pandemic knocking at the door

    Martin Michaelis;Hans Wilhelm Doerr;Jindrich Cinatl

  • Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses

    Martin Michaelis;Hans Wilhelm Doerr;Jindrich Cinatl

Frequent Co-Authors

Jindrich Cinatl
Jindrich Cinatl Goethe University Frankfurt
Hans Wilhelm Doerr
Hans Wilhelm Doerr Goethe University Frankfurt
Sandra Ciesek
Sandra Ciesek Goethe University Frankfurt
Michael Wiese
Michael Wiese University of Bonn
Franz Rödel
Franz Rödel Goethe University Frankfurt
Holger F. Rabenau
Holger F. Rabenau Goethe University Frankfurt
Oliver T. Keppler
Oliver T. Keppler Ludwig-Maximilians-Universität München
Frank Westermann
Frank Westermann German Cancer Research Center
Rainer Breitling
Rainer Breitling University of Manchester
Gerd Geisslinger
Gerd Geisslinger Goethe University Frankfurt

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