Eiji Hara

Overview

Best Publications

• Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

  Shin Yoshimoto;Tze Mun Loo;Tze Mun Loo;Koji Atarashi;Hiroaki Kanda

  2386
  Citations

• Cellular Senescence: Defining a Path Forward

  Vassilis Gorgoulis;Peter D. Adams;Andrea Alimonti;Dorothy C. Bennett

  2153
  Citations

• An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

  Marco Demaria;Naoko Ohtani;Sameh A Youssef;Francis Rodier

  1764
  Citations

• The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

  Francesca J. Stott;Stewart Bates;Marion C. James;Beth B. McConnell

  1685
  Citations

• Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence.

  E Hara;R Smith;D Parry;H Tahara

  1053
  Citations

• Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence.

  Naoko Ohtani;Zoe Zebedee;Thomas J. G. Huot;Julie A. Stinson

  803
  Citations

• Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

  Akiko Takahashi;Ryo Okada;Koji Nagao;Yuka Kawamata

  687
  Citations

• Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence.

  Akiko Takahashi;Naoko Ohtani;Kimi Yamakoshi;Shin Ichi Iida

  574
  Citations

• Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts.

  E Hara;T Yamaguchi;H Nojima;T Ide

  467
  Citations

• Genotoxic Stress Abrogates Renewal of Melanocyte Stem Cells by Triggering Their Differentiation

  Ken Inomata;Takahiro Aoto;Takahiro Aoto;Nguyen Thanh Binh;Natsuko Okamoto;Natsuko Okamoto

  445
  Citations

• Id proteins in cell cycle control and cellular senescence

  Zoe Zebedee;Eiji Hara

  391
  Citations

• The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression.

  Naoko Ohtani;Kimi Yamakoshi;Akiko Takahashi;Eiji Hara

  361
  Citations

• Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity.

  Tze Mun Loo;Fumitaka Kamachi;Yoshihiro Watanabe;Shin Yoshimoto

  359
  Citations

• Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

  Masaki Takasugi;Ryo Okada;Akiko Takahashi;David Virya Chen

  332
  Citations

• Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

  Akiko Takahashi;Tze Mun Loo;Tze Mun Loo;Ryo Okada;Fumitaka Kamachi

  325
  Citations

• Impact of senescence-associated secretory phenotype and its potential as a therapeutic target for senescence-associated diseases.

  Sugiko Watanabe;Shimpei Kawamoto;Naoko Ohtani;Eiji Hara;Eiji Hara

  304
  Citations

• Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1.

  P Y Desprez;E Hara;M J Bissell;J Campisi

  258
  Citations

• Subtractive cDNA cloning using oligo(dt)30-latex and PCR: isolation of cDNA clones specific to undifferentiated human embryonal carcinoma cells

  Eiji Hara;Tomohiro Kato;Susumu Nakada;Souei Sekiya

  244
  Citations

• DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells.

  Akiko Takahashi;Yoshinori Imai;Kimi Yamakoshi;Shinji Kuninaka

  232
  Citations

• Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

  Kimi Yamakoshi;Akiko Takahashi;Fumiko Hirota;Rika Nakayama

  204
  Citations