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Microbiology

D-Index
56
Citations
10102
World Ranking
3723
National Ranking
149

Overview

Yoshio Hayashi is affiliated with the University of Tokushima in Japan and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, as well as medicine. Their research spans multiple subfields including molecular biology, organic chemistry, radiology and nuclear medicine, materials chemistry, and physiology. The scientist's work encompasses a variety of topics such as chemical synthesis and analysis, muscle physiology and disorders, monoclonal and polyclonal antibodies research, microbial natural products and biosynthesis, receptor mechanisms and signaling, antimicrobial peptides and activities, and click chemistry applications.

Their publication record includes papers in prominent scientific journals and covers recent years with a focus on medicinal chemistry, cancer science, and organic chemistry. Some of the recent papers authored or coauthored by Yoshio Hayashi include:

  • 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents, 2021, Journal of Medicinal Chemistry
  • Functionalized mesoporous silica nanoparticles for innovative boron-neutron capture therapy of resistant cancers, 2020, Nanomedicine Nanotechnology Biology and Medicine
  • "On-Resin" Disulfide Peptide Synthesis with Methyl 3-Nitro-2-pyridinesulfenate, 2020, European Journal of Organic Chemistry
  • Combination therapy with anamorelin and a myostatin inhibitor is advantageous for cancer cachexia in a mouse model, 2022, Cancer Science
  • Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application, 2021, The Journal of Organic Chemistry

Yoshio Hayashi frequently collaborates with other researchers. The most frequent coauthors include Atsuhiko Taniguchi, Akihiro Taguchi, Kentaro Takayama, Sho Konno, and Kyohei Muguruma.

Their research outputs are commonly published in several venues, with multiple publications in the following journals:

  • ACS Medicinal Chemistry Letters
  • Chemical and Pharmaceutical Bulletin
  • Journal of Medicinal Chemistry
  • Cancer Science
  • Bioorganic & Medicinal Chemistry

Best Publications

  • Identification of α-Fodrin as a Candidate Autoantigen in Primary Sjögren's Syndrome

    Norio Haneji;Takanori Nakamura;Koji Takio;Kumiko Yanagi

  • The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

    Yu Hikosaka;Takeshi Nitta;Izumi Ohigashi;Kouta Yano

  • Revised Japanese criteria for Sjögren’s syndrome (1999): availability and validity

    Takashi Fujibayashi;Susumu Sugai;Nobuyuki Miyasaka;Yoshio Hayashi

  • CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance.

    Hirotsugu Kurobe;Cunlan Liu;Tomoo Ueno;Tomoo Ueno;Fumi Saito

  • Development of Autoimmunity against Transcriptionally Unrepressed Target Antigen in the Thymus of Aire-Deficient Mice

    Noriyuki Kuroda;Tasuku Mitani;Naoki Takeda;Naozumi Ishimaru

  • Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

    Yu Lei;Yu Lei;Adiratna Mat Ripen;Naozumi Ishimaru;Izumi Ohigashi

  • Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity

    Kaoru Saegusa;Naozumi Ishimaru;Kumiko Yanagi;Rieko Arakaki

  • Slower immune system aging in women versus men in the Japanese population

    Katsuiku Hirokawa;Masanori Utsuyama;Yoshio Hayashi;Masanobu Kitagawa

  • Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

    Kimi Yamakoshi;Akiko Takahashi;Fumiko Hirota;Rika Nakayama

  • Transgenic expression of IL-10 in pancreatic islet A cells accelerates autoimmune insulitis and diabetes in non-obese diabetic mice.

    Maki Moritani;Katsuhiko Yoshimoto;Fumi Tashiro;Chikara Hashimoto

  • Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands.

    Miriam Entesarian;Hans Matsson;Joakim Klar;Birgitta Bergendal

  • A new animal model for primary Sjögren's syndrome in NFS/sld mutant mice.

    N Haneji;H Hamano;K Yanagi;Y Hayashi

  • Fas ligand-mediated exocrinopathy resembling Sjögren's syndrome in mice transgenic for IL-10.

    Ichiro Saito;Kumiko Haruta;Misa Shimuta;Hiroko Inoue

  • Estrogen deficiency accelerates autoimmune exocrinopathy in murine Sjögren's syndrome through fas-mediated apoptosis

    Naozumi Ishimaru;Kaoru Saegusa;Kumiko Yanagi;Norio Haneji

  • Rapid isolation of nucleoli from detergent purified nuclei of various tumor and tissue culture cells

    M. Muramatsu;Y. Hayashi;T. Onishi;M. Sakai

  • Mechanism of Activation-Induced Cell Death of T Cells and Regulation of FasL Expression

    Rieko Arakaki;Akiko Yamada;Yasusei Kudo;Yoshio Hayashi

  • Development of Autoimmune Exocrinopathy Resembling Sjögren's Syndrome in Estrogen-Deficient Mice of Healthy Background

    Naozumi Ishimaru;Rieko Arakaki;Megumi Watanabe;Masaru Kobayashi

  • Spontaneous development of organ-specific autoimmune lesions in aged C57BL/6 mice.

    Y Hayashi;M Utsuyama;C Kurashima;K Hirokawa

  • Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome–like autoimmune exocrinopathy

    Naozumi Ishimaru;Rieko Arakaki;Satoko Yoshida;Akiko Yamada

  • Regulation of naive T cell function by the NF-|[kappa]|B2 pathway

    Naozumi Ishimaru;Hidehiro Kishimoto;Yoshio Hayashi;Jonathan Sprent;Jonathan Sprent

  • Polarizing activity, Sonic hedgehog, and tooth development in embryonic and postnatal mouse.

    Eiki Koyama;Tomoichiro Yamaai;Sachiko Iseki;Hideyo Ohuchi

Frequent Co-Authors

Kazuo Tsubota
Kazuo Tsubota Keio University
Yasusei Kudo
Yasusei Kudo University of Tokushima
Sumihare Noji
Sumihare Noji University of Tokushima
Yousuke Takahama
Yousuke Takahama National Institutes of Health
Eiji Tanaka
Eiji Tanaka Shinshu University
Hideyo Ohuchi
Hideyo Ohuchi Okayama University
Mitsuru Matsumoto
Mitsuru Matsumoto University of Tokushima
Henrik J. Ditzel
Henrik J. Ditzel University of Southern Denmark
Mitsuo Itakura
Mitsuo Itakura University of Tokushima
Atsushi Hirao
Atsushi Hirao Kanazawa University

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