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D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
20395
World Ranking
6574
National Ranking
3060

Overview

Daohong Zhou is affiliated with the University of Florida in the United States and specializes primarily in the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. Their research emphasizes molecular biology, oncology, hematology, physiology, and immunology, reflecting a broad interdisciplinary approach.

They have published extensively, with a total of 154 works related to biochemistry and molecular biology and 141 works connected to medicine. Subfields such as molecular biology (132 publications), oncology (54), and hematology (32) feature prominently among their scientific outputs.

Their main research topics include protein degradation and inhibitors, multiple myeloma research and treatments, ubiquitin and proteasome pathways, peptidase inhibition and analysis, telomeres, telomerase and senescence, histone deacetylase inhibitors research, and PARP inhibition in cancer therapy.

Daohong Zhou has collaborated frequently with several researchers, including Guangrong Zheng (62 coauthored works), Peiyi Zhang (32), Xuan Zhang (24), Yaxia Yuan (24), and Sajid Khan (22).

The venues where Zhou has published most frequently include Cancer Research (19 publications), Blood (9), bioRxiv (Cold Spring Harbor Laboratory) (8), Nature Communications (5), and Aging Cell (4).

Recent selected publications are:

  • Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy, 2021, JNCI Journal of the National Cancer Institute
  • Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity, 2020, Nature Communications
  • IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis, 2020, Journal of Clinical Investigation
  • PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics, 2020, Oncogene
  • Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity, 2021, Nature Communications

Best Publications

  • Cellular Senescence: Defining a Path Forward

    Vassilis Gorgoulis;Peter D. Adams;Andrea Alimonti;Dorothy C. Bennett

  • Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.

    Jianhui Chang;Yingying Wang;Yingying Wang;Lijian Shao;Remi Martin Laberge

  • Cellular senescence promotes adverse effects of chemotherapy and cancer relapse

    Marco Demaria;Marco Demaria;Monique N. O'Leary;Jianhui Chang;Lijian Shao

  • Exposure to physical and psychological stressors elevates plasma interleukin 6: relationship to the activation of hypothalamic-pituitary-adrenal axis

    Daohong Zhou;Alexander Kusnecov;Michael R. Shurin;Melissa Depaoli

  • A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity

    Sajid Khan;Xuan Zhang;Dongwen Lv;Qi Zhang

  • Total body irradiation selectively induces murine hematopoietic stem cell senescence

    Yong Wang;Bradley A. Schulte;Bradley A. Schulte;Amanda C. LaRue;Amanda C. LaRue;Makio Ogawa;Makio Ogawa

  • Reactive oxygen species in normal and tumor stem cells.

    Daohong Zhou;Lijian Shao;Douglas R. Spitz

  • Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells

    Yong Wang;Lingbo Liu;Lingbo Liu;Senthil K. Pazhanisamy;Hongliang Li;Hongliang Li

  • Hematopoietic Stem Cell Injury Induced by Ionizing Radiation

    Lijian Shao;Yi Luo;Daohong Zhou

  • Lack of the p50 subunit of nuclear factor-κb increases the vulnerability of hippocampal neurons to excitotoxic injury

    ZaiFang Yu;Daohong Zhou;Annadora J. Bruce-Keller;Mark S. Kindy

  • Sphingosine kinase 1 is up-regulated in colon carcinogenesis.

    Toshihiko Kawamori;Walid Osta;Korey R. Johnson;Benjamin J. Pettus

  • Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells.

    Aimin Meng;Yong Wang;Gary Van Zant;Daohong Zhou

  • Discovery of piperlongumine as a potential novel lead for the development of senolytic agents.

    Yingying Wang;Jianhui Chang;Xingui Liu;Xuan Zhang

  • Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis.

    Zai Fang Yu;Mariana Nikolova-Karakashian;Daohong Zhou;Guanjun Cheng

  • Inhibition of Bcl-2/xl With ABT-263 Selectively Kills Senescent Type II Pneumocytes and Reverses Persistent Pulmonary Fibrosis Induced by Ionizing Radiation in Mice.

    Jin Pan;Deguan Li;Yanfeng Xu;Junling Zhang

  • Therapy-induced senescence: opportunities to improve anti-cancer therapy

    Pataje G Prasanna;Deborah E Citrin;Jeffrey Hildesheim;Mansoor M Ahmed

  • Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition

    Søren M. Johnson;Chad D. Torrice;Jessica F. Bell;Kimberly B. Monahan

  • Ionizing Radiation-Induced Endothelial Cell Senescence and Cardiovascular Diseases

    Yingying Wang;Marjan Boerma;Daohong Zhou

  • Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

    Yonghan He;Xuan Zhang;Jianhui Chang;Ha Neui Kim

  • Total Body Irradiation Causes Residual Bone Marrow Injury by Induction of Persistent Oxidative Stress in Murine Hematopoietic Stem Cells.

    Yong Wang;Lingbo Liu;Senthil Kumar Pazhanisamy;Aimin Meng

Frequent Co-Authors

Judith Campisi
Judith Campisi Buck Institute for Research on Aging
Robert Hromas
Robert Hromas The University of Texas Health Science Center at San Antonio
Norman E. Sharpless
Norman E. Sharpless National Institutes of Health
Marco Demaria
Marco Demaria University Medical Center Groningen
Makio Ogawa
Makio Ogawa Medical University of South Carolina
Jeannette Y. Lee
Jeannette Y. Lee University of Arkansas for Medical Sciences
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Bruce S. Rabin
Bruce S. Rabin University of Pittsburgh
Elizabeth A. Williamson
Elizabeth A. Williamson London School of Hygiene & Tropical Medicine
Hartmut Geiger
Hartmut Geiger University of Ulm

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