World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
16379
World Ranking
6721
National Ranking
3118

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Robert Hromas is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research covers multiple areas primarily within biochemistry, genetics, and molecular biology, with a significant focus on medicine.

The scientist's extensive publication record includes 106 works in the main field of Biochemistry, Genetics and Molecular Biology and 51 works in Medicine. Subfields of study include Molecular Biology, Oncology, Cancer Research, Hematology, and Immunology.

Key topics in their research are:

  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • CRISPR and Genetic Engineering
  • Protein Degradation and Inhibitors
  • Ubiquitin and proteasome pathways
  • RNA modifications and cancer
  • Peptidase Inhibition and Analysis

The scientist has published multiple papers in notable journals, including Nature Communications, Cancer Research, Journal of Clinical Oncology, and Molecular Cancer Therapeutics. Frequent publication venues include:

  • Nature Communications (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)
  • Cancer Research (4 publications)
  • Journal of Clinical Oncology (3 publications)
  • Molecular Cancer Therapeutics (2 publications)

Some recent papers authored or co-authored by Robert Hromas are:

  • Structural basis of RNA cap modification by SARS-CoV-2, 2020, Nature Communications
  • Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity, 2021, Nature Communications
  • Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies, 2020, Journal of Hematology & Oncology
  • M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression, 2022, Cancer Research
  • Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216, 2021, Molecular Cancer Therapeutics

Robert Hromas has frequently collaborated with several researchers. The most frequent co-authors are:

  • Daohong Zhou (21 collaborations)
  • Patrick Sung (16 collaborations)
  • Elizabeth A. Williamson (15 collaborations)
  • Weixing Zhao (10 collaborations)
  • Sandeep Burma (10 collaborations)

They have been recognized as a member of the Association of American Physicians. This membership signifies an acknowledgment within the medical and scientific community.

Best Publications

  • Transcription factors, normal myeloid development, and leukemia.

    Daniel G. Tenen;Robert Hromas;Jonathan D. Licht;Dong-Er Zhang

  • The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

    William A. May;Stephen L. Lessnick;Benjamin S. Braun;Michael Klemsz

  • Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.

    Trevor Starnes;Michael J. Robertson;George Sledge;Stephanie Kelich

  • Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis.

    Trevor Starnes;Hal E. Broxmeyer;Michael J. Robertson;Robert A Hromas

  • A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity

    Sajid Khan;Xuan Zhang;Dongwen Lv;Qi Zhang

  • Drug Repurposing from an Academic Perspective.

    Tudor I. Oprea;Julie E. Bauman;Cristian G. Bologa;Tione Buranda

  • Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

    Sheema Fnu;Elizabeth A. Williamson;Leyma P. De Haro;Mark Brenneman

  • Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells.

    Rafat Abonour;David A. Williams;Lawrence Einhorn;Kristin M. Hall

  • PLAB, a novel placental bone morphogenetic protein.

    Robert Hromas;Matthew Hufford;Jill Sutton;Dawei Xu

  • Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1

    R Hromas;A Orazi;RS Neiman;R Maki

  • A retinoic acid-responsive human zinc finger gene, MZF-1, preferentially expressed in myeloid cells.

    R Hromas;S J Collins;D Hickstein;W Raskind

  • Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells.

    Jill Sutton;Robert Costa;Michael Klug;Loren Field

  • Cloning of BRAK, a Novel Divergent CXC Chemokine Preferentially Expressed in Normal versus Malignant Cells

    Robert Hromas;Hal E. Broxmeyer;Chang Kim;Harikrishna Nakshatri

  • Synthetic lethality: exploiting the addiction of cancer to DNA repair

    Montaser Shaheen;Christopher Allen;Jac A. Nickoloff;Robert A Hromas

  • Cloning and Characterization of Exodus, a Novel β-Chemokine

    Robert Hromas;Patrick W. Gray;David Chantry;Ronald Godiska

  • Structural basis of RNA cap modification by SARS-CoV-2.

    Thiruselvam Viswanathan;Shailee Arya;Shailee Arya;Siu Hong Chan;Shan Qi;Shan Qi

  • Update on Late Relapse of Germ Cell Tumor: A Clinical and Molecular Analysis

    David W. George;Richard S. Foster;Robert A. Hromas;Robert A. Hromas;Kent A. Robertson

  • The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression

    Ying Guo;Robert Costa;Heather Ramsey;Trevor Starnes

  • The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair

    Suk Hee Lee;Masahiko Oshige;Stephen T. Durant;Kanwaldeep Kaur Rasila

  • Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension.

    Robert Hromas;Chang H. Kim;Michael Klemsz;Mitchell Krathwohl

Frequent Co-Authors

Elizabeth A. Williamson
Elizabeth A. Williamson London School of Hygiene & Tropical Medicine
Hal E. Broxmeyer
Hal E. Broxmeyer Indiana University
Jac A. Nickoloff
Jac A. Nickoloff Colorado State University
Kenneth Cornetta
Kenneth Cornetta Indiana University
Patrick Sung
Patrick Sung The University of Texas Health Science Center at San Antonio
Edward F. Srour
Edward F. Srour Indiana University
Daohong Zhou
Daohong Zhou University of Florida
Chang H. Kim
Chang H. Kim University of Michigan–Ann Arbor
Larry A. Sklar
Larry A. Sklar University of New Mexico
Cheryl L. Willman
Cheryl L. Willman University of New Mexico

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