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Medicine

D-Index
77
Citations
18489
World Ranking
18545
National Ranking
617

Overview

Samuel N. Breit is affiliated with the University of New South Wales in Australia. Their research spans across multiple fields primarily focused on Medicine and Immunology and Microbiology, with specific contributions to Rheumatology, Immunology, Physiology, Molecular Biology, and Cellular and Molecular Neuroscience.

The scientist's work centers on a range of topics, with a significant emphasis on GDF15 and Related Biomarkers. Other prominent areas of study include Nutrition and Health in Aging, Macrophage Migration Inhibitory Factor, Nuclear Receptors and Signaling, Genetics and Neurodevelopmental Disorders, Liver Disease Diagnosis and Treatment, and IL-33, ST2, and ILC Pathways.

Samuel N. Breit has published several research articles, including:

  • The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe? (2020, Annual Review of Physiology)
  • GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway (2023, Cell Metabolism)
  • GDF15 analogs as obesity therapeutics (2023, Cell Metabolism)

Frequent collaboration has been a part of their career, with notable co-authors including:

  • David A. Brown (11 joint publications)
  • Vicky Wang-Wei Tsai (8 joint publications)
  • Anthony D. Kelleher (3 joint publications)
  • Steven Q. Le (3 joint publications)
  • Marisa Alves (3 joint publications)

Samuel N. Breit's research has been featured in several recurring publication venues. The most frequent venues include Pathology, Scientific Reports, Cell Metabolism, Nature Metabolism, and Annual Review of Physiology.

Best Publications

  • MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily

    Michelle R. Bootcov;Asne R. Bauskin;Stella M. Valenzuela;Anthony G. Moore

  • Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.

    Heiko Johnen;Shu Lin;Tamara Kuffner;David A. Brown

  • GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation

    Jian Xu;Thomas R. Kimball;John N. Lorenz;David A. Brown

  • Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

    John B. Welsh;Lisa M. Sapinoso;Suzanne G. Kern;David A. Brown

  • Radiation and the Lung: A Reevaluation of the Mechanisms Mediating Pulmonary Injury

    Graeme Morgan;Samuel Breit

  • Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study

    David A Brown;Samuel N Breit;Julie Buring;W Douglas Fairlie

  • Role of Macrophage Inhibitory Cytokine-1 in Tumorigenesis and Diagnosis of Cancer

    Asne R. Bauskin;David A. Brown;Tamara Kuffner;Heiko Johnen

  • Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers

    Jens Koopmann;Phillip Buckhaults;David A. Brown;Marianna L. Zahurak

  • MIC‐1 is a novel TGF‐β superfamily cytokine associated with macrophage activation

    W D Fairlie;A G Moore;A R Bauskin;P K Russell

  • MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.

    David A. Brown;Robyn L. Ward;Philip Buckhaults;Tao Liu

  • Scleroderma lung disease

    Joshua J. Solomon;Amy L. Olson;Amy L. Olson;Aryeh Fischer;Aryeh Fischer;Todd Bull;Todd Bull

  • Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9.

    Jens Koopmann;C. Nicole White Rosenzweig;Zhen Zhang;Marcia I. Canto

  • The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases

    Vicky W.W. Tsai;Vicky W.W. Tsai;Yasmin Husaini;Yasmin Husaini;Amanda Sainsbury;David A. Brown;David A. Brown

  • Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality

    Fredrik E. Wiklund;Anna M. Bennet;Patrik K. E. Magnusson;Ulrika K. Eriksson

  • The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism.

    Samuel N. Breit;Heiko Johnen;Andrew D. Cook;Vicky W. W. Tsai

  • The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition.

    Dene R. Littler;Stephen J. Harrop;W. Douglas Fairlie;Louise J. Brown

  • Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.

    S.J Harrop;M.Z DeMaere;W.D Fairlie;T Reztsova

  • Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells.

    Tao Liu;Asne R. Bauskin;John Zaunders;David A. Brown

  • Radiation Pneumonitis: A Possible Lymphocyte-mediated Hypersensitivity Reaction

    C M Roberts;E Foulcher;J J Zaunders;D H Bryant

  • The transforming growth factor-ss superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women.

    A. G. Moore;D. A. Brown;W. D. Fairlie;A. R. Bauskin

Frequent Co-Authors

Ronald Penny
Ronald Penny University of New South Wales
Paul M. G. Curmi
Paul M. G. Curmi University of New South Wales
Amanda Sainsbury
Amanda Sainsbury University of Western Australia
Bruce D. Walker
Bruce D. Walker Harvard University
Pamela J. Russell
Pamela J. Russell Queensland University of Technology
W. Douglas Fairlie
W. Douglas Fairlie La Trobe University
Denis Wakefield
Denis Wakefield University of New South Wales
Herbert Herzog
Herbert Herzog Garvan Institute of Medical Research
Anthony D. Kelleher
Anthony D. Kelleher University of New South Wales
Marc J. Ruitenberg
Marc J. Ruitenberg University of Queensland

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