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Immunology

D-Index
57
Citations
12089
World Ranking
3624
National Ranking
1674

Overview

John Zaunders is affiliated with Ascension Health in the United States. Their research primarily focuses on immunology and microbiology, with notable contributions to medicine. The scientist's work spans various subfields, including immunology, infectious diseases, virology, epidemiology, and neurology.

Zaunders has explored key topics such as T-cell and B-cell immunology, HIV research and treatment, immune cell function and interaction, immunotherapy and immune responses, SARS-CoV-2 and COVID-19 research, cytomegalovirus and herpesvirus research, and neuroinflammation and neurodegeneration mechanisms.

Several recent publications illustrate the scope and detail of their research. These include:

  • Zeb2 drives the formation of CD11c + atypical B cells to sustain germinal centers that control persistent infection (2024, Science Immunology)
  • Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury (2022, Proceedings of the National Academy of Sciences)
  • Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19 (2022, Clinical Immunology)
  • HIV-1 viral blips are associated with repeated and increasingly high levels of cell-associated HIV-1 RNA transcriptional activity (2021, AIDS)
  • Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulcerative colitis (2020, Clinical & Experimental Immunology)

Zaunders' collaborative work is highlighted by frequent coauthors, including Anthony D. Kelleher, C. Mee Ling Munier, Kazuo Suzuki, Angelique Levert-Mignon, and Takaomi Ishida.

The scientist has published extensively in prominent venues, with multiple publications appearing in:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • AIDS
  • SSRN Electronic Journal
  • iScience

Best Publications

  • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

    Nabila Seddiki;Nabila Seddiki;Brigitte Santner-Nanan;Jeff Martinson;John Zaunders

  • Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.

    Daniel E Kaufmann;Daniel G Kavanagh;Florencia Pereyra;Florencia Pereyra;John J Zaunders

  • Characterization of CD4(+) CTLs ex vivo.

    Victor Appay;John J. Zaunders;Laura Papagno;Julian Sutton

  • Alterations in the Immune Response of Human Immunodeficiency Virus (HIV)-Infected Subjects Treated with an HIV-Specific Protease Inhibitor, Ritonavir

    A. D. Kelleher;A. Carr;J. Zaunders;D. A. Cooper

  • Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells.

    Tao Liu;Asne R. Bauskin;John Zaunders;David A. Brown

  • Radiation Pneumonitis: A Possible Lymphocyte-mediated Hypersensitivity Reaction

    C M Roberts;E Foulcher;J J Zaunders;D H Bryant

  • The extent of HIV-1-related immunodeficiency and age predict the long-term CD4 T lymphocyte response to potent antiretroviral therapy.

    Gilbert R Kaufmann;Mark Bloch;Robert Finlayson;John Zaunders

  • Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection.

    John J. Zaunders;Wayne B. Dyer;Bin Wang;Mee Ling Munier

  • High Levels of Human Antigen-Specific CD4+ T Cells in Peripheral Blood Revealed by Stimulated Coexpression of CD25 and CD134 (OX40)

    John J. Zaunders;Mee Ling Munier;Nabila Seddiki;Sarah Pett

  • Cytotoxic CD4 T Cells-Friend or Foe during Viral Infection?

    Jennifer A. Juno;David van Bockel;Stephen J. Kent;Stephen J. Kent;Anthony D. Kelleher;Anthony D. Kelleher

  • Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia.

    J. Ho;M. Bailey;J. Zaunders;N. Mrad

  • HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis

    Delphine Sauce;Martin Larsen;Solène Fastenackels;Michèle Pauchard

  • Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region.

    Kazuo Suzuki;Toshiaki Shijuuku;Toshihiko Fukamachi;John Zaunders

  • HIV-1–specific cytotoxicity is preferentially mediated by a subset of CD8+ T cells producing both interferon-γ and tumor necrosis factor–α

    Mathias Lichterfeld;Xu G. Yu;Michael T. Waring;Stanley K. Mui

  • Increased natural killer cell activity in viremic HIV-1 infection.

    Galit Alter;Jessica M. Malenfant;Rosemary M. Delabre;Nicole C. Burgett

  • Human mesenchymal stem cells constitutively express chemokines and chemokine receptors that can be upregulated by cytokines, IFN-beta, and Copaxone.

    Juliana Croitoru-Lamoury;Francois M.J. Lamoury;John J. Zaunders;Laura A. Veas

  • Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after age twenty

    John M Murray;Gilbert R Kaufmann;Philip D Hodgkin;Sharon R Lewin

  • Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques

    Yin Xu;Chris Weatherall;Michelle Bailey;Sheilajen Alcantara

  • Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection.

    Sarah C Sasson;John J Zaunders;Giulia Zanetti;Eleanor M King

  • HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism

    Davide Genini;Dennis Sheeter;Steffney Rought;John J. Zaunders

  • Patterns of Viral Dynamics during Primary Human Immunodeficiency Virus Type 1 Infection

    Gilbert R. Kaufmann;Philip Cunningham;Anthony D. Kelleher;John Zaunders

Frequent Co-Authors

Anthony D. Kelleher
Anthony D. Kelleher University of New South Wales
David A. Cooper
David A. Cooper University of New South Wales
Kazuo Suzuki
Kazuo Suzuki Teikyo University
Andrew Carr
Andrew Carr University of Oxford
Stephen J. Kent
Stephen J. Kent University of Melbourne
Sharon R. Lewin
Sharon R. Lewin University of Melbourne
Sean Emery
Sean Emery University of New South Wales
Ronald Penny
Ronald Penny University of New South Wales
Paul R. Gorry
Paul R. Gorry RMIT University
Carole Elbim
Carole Elbim Sorbonne University

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