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Peter A. Smith

Peter A. Smith

D-Index & Metrics

Neuroscience

D-Index
37
Citations
4842
World Ranking
8840
National Ranking
522

Overview

Peter A. Smith is a researcher affiliated with the University of Alberta in Canada. Their academic focus spans the fields of medicine and neuroscience, with notable contributions to subfields including physiology, cellular and molecular neuroscience, molecular biology, neurology, and pharmacology.

The primary topics explored in their research revolve around pain mechanisms and treatments, neuropeptides and animal physiology, ion channel regulation and function, nerve injury and regeneration, botulinum toxin and related neurological disorders, exercise and physiological responses, and pharmacological effects of natural compounds.

Smith has published extensively, with recent papers including:

  • K+ Channels in Primary Afferents and Their Role in Nerve Injury-Induced Pain, 2020, Frontiers in Cellular Neuroscience
  • Neuropathic pain; what we know and what we should do about it, 2023, Frontiers in Pain Research

Other significant papers in the broader context of their field, authored by frequent collaborators, are:

  • Mediators of Neuropathic Pain; Focus on Spinal Microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt Ligands, and Interleukin 1β, 2021, Frontiers in Pain Research
  • Peripheral Voltage-Gated Cation Channels in Neuropathic Pain and Their Potential as Therapeutic Targets, 2021, Frontiers in Pain Research
  • Time Course of Inflammation in Dorsal Root Ganglia Correlates with Differential Reversibility of Mechanical Allodynia, 2020, Neuroscience

Their frequent coauthors include:

  • Sascha R.A. Alles
  • Daniel K. Treiber
  • Brian L. Hodous
  • Max A. Odem
  • Van B. Lu

Smith's research has appeared primarily in the following venues:

  • Frontiers in Pain Research
  • Neuroscience
  • Journal of Investigative Dermatology
  • Frontiers in Cellular Neuroscience
  • Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

Their body of work predominantly addresses the molecular and cellular underpinnings of neuropathic pain and nerve injury. This includes investigating ion channels such as K+ channels in sensory neurons and the neuroinflammatory pathways involved in pain signaling. Their research also intersects with studies on neuropeptides, neuroimmune factors, and pharmacological agents that could modulate pain responses.

Best Publications

  • Etiology and Pharmacology of Neuropathic Pain

    Sascha R. A. Alles;Peter A. Smith

  • Axotomy- and Autotomy-Induced Changes in Ca2+and K+ Channel Currents of Rat Dorsal Root Ganglion Neurons

    Fuad A. Abdulla;Peter A. Smith

  • Axotomy- and Autotomy-Induced Changes in the Excitability of Rat Dorsal Root Ganglion Neurons

    Fuad A. Abdulla;Peter A. Smith

  • Is BDNF Sufficient for Information Transfer between Microglia and Dorsal Horn Neurons during the Onset of Central Sensitization

    James E Biggs;Van B Lu;Martin J Stebbing;Sridhar Balasubramanyan

  • Sciatic chronic constriction injury produces cell-type-specific changes in the electrophysiological properties of rat substantia gelatinosa neurons.

    Sridhar Balasubramanyan;Patrick L. Stemkowski;Martin J. Stebbing;Peter A. Smith

  • Ectopic alpha2-adrenoceptors couple to N-type Ca2+ channels in axotomized rat sensory neurons.

    Fuad A. Abdulla;Peter A. Smith

  • Nociceptin Inhibits T-Type Ca2+ Channel Current in Rat Sensory Neurons by a G-Protein-Independent Mechanism

    Fuad A. Abdulla;Peter A. Smith

  • Brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury.

    Van B. Lu;James E. Biggs;Martin J. Stebbing;Sridhar Balasubramanyan

  • BDNF: no gain without pain?

    Peter A. Smith

  • Axotomy Reduces the Effect of Analgesic Opioids Yet Increases the Effect of Nociceptin on Dorsal Root Ganglion Neurons

    Fuad A. Abdulla;Peter A. Smith

  • Nerve injury increases an excitatory action of neuropeptide Y and Y2-agonists on dorsal root ganglion neurons

    F.A. Abdulla;P.A. Smith

  • Spinal mechanisms of NPY analgesia

    Peter A. Smith;Timothy D. Moran;Fuad Abdulla;Kiranjeet K. Tumber

  • Peripheral Voltage-Gated Cation Channels in Neuropathic Pain and Their Potential as Therapeutic Targets

    Unknown

  • Sensory neurons, ion channels, inflammation and the onset of neuropathic pain.

    Patrick L. Stemkowski;Peter A. Smith

  • Electrophysiological characteristics of hamster dorsal root ganglion cells and their response to axotomy

    S. Gurtu;P. A. Smith

  • Changes in Na+ Channel Currents of Rat Dorsal Root Ganglion Neurons Following Axotomy and Axotomy-Induced Autotomy

    Fuad A. Abdulla;Peter A. Smith

  • Distance Education and the Mainstream: Convergence in Education

    Peter Smith;Kelly Mavis

  • Neuron type-specific effects of brain-derived neurotrophic factor in rat superficial dorsal horn and their relevance to 'central sensitization'.

    Van B. Lu;Klaus Ballanyi;William F. Colmers;Peter A. Smith

  • Mediators of Neuropathic Pain; Focus on Spinal Microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt Ligands, and Interleukin 1β

    Paul A. Boakye;Shao-Jun Tang;Peter A. Smith

  • Opioid-Like Actions of Neuropeptide Y in Rat Substantia Gelatinosa: Y1 Suppression of Inhibition and Y2 Suppression of Excitation

    Timothy D. Moran;William F. Colmers;Peter A. Smith

  • Cellular neurophysiological actions of nociceptin/orphanin FQ.

    Timothy D. Moran;Fuad A. Abdulla;Peter A. Smith

  • HIV-1 viral protein R causes peripheral nervous system injury associated with in vivo neuropathic pain

    Shaona Acharjee;Farshid Noorbakhsh;Patrick L. Stemkowski;Camille Olechowski

Frequent Co-Authors

Klaus Ballanyi
Klaus Ballanyi University of Alberta
William F. Colmers
William F. Colmers University of Alberta
Tessa Gordon
Tessa Gordon University of Alberta
Bradley J. Kerr
Bradley J. Kerr University of Alberta
Lars Olson
Lars Olson Karolinska Institute
Bradley K. Taylor
Bradley K. Taylor University of Pittsburgh
Richard B. Stein
Richard B. Stein University of Alberta
Shawn Hochman
Shawn Hochman Emory University
Quinn H. Hogan
Quinn H. Hogan Medical College of Wisconsin
Éric A. Cohen
Éric A. Cohen University of Montreal

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