World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
76
Citations
20672
World Ranking
1922
National Ranking
920

Overview

Theodore R. Cummins is affiliated with Indiana University - Purdue University Indianapolis in the United States. Their research spans multiple fields of study, primarily focusing on Biochemistry, Genetics and Molecular Biology, with notable contributions to Medicine.

The main subfields of study include:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Genetics

Their research covers a range of scientific topics such as:

  • Ion channel regulation and function
  • Neuroscience and Neuropharmacology Research
  • Nicotinic Acetylcholine Receptors Study
  • Cardiac electrophysiology and arrhythmias
  • Pain Mechanisms and Treatments
  • Retinal Development and Disorders
  • Retinopathy of Prematurity Studies

Theodore R. Cummins has published extensively, with frequent appearances in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Stem Cell Reports
  • Cells
  • UNC Libraries
  • Journal of Biological Chemistry

Significant recent publications include:

  • Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids (2020, Stem Cell Reports)
  • CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability (2020, Journal of Biological Chemistry)
  • Distinctive Properties and Powerful Neuromodulation of Nav1.6 Sodium Channels Regulates Neuronal Excitability (2021, Cells)
  • Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967 (2020, International Journal of Molecular Sciences)
  • Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN(E50K) human stem cell-derived retinal ganglion cells (2022, Stem Cell Reports)

Theodore R. Cummins has collaborated frequently with coauthors such as:

  • Yucheng Xiao
  • Agnes Zybura
  • Yanling Pan
  • Kirstin B. VanderWall
  • Kang-Chieh Huang

Best Publications

  • DOWNREGULATION OF TETRODOTOXIN-RESISTANT SODIUM CURRENTS AND UPREGULATION OF A RAPIDLY REPRIMING TETRODOTOXIN-SENSITIVE SODIUM CURRENT IN SMALL SPINAL SENSORY NEURONS AFTER NERVE INJURY

    Theodore R. Cummins;Stephen G. Waxman

  • Sodium Channels in Normal and Pathological Pain

    Sulayman D. Dib-Hajj;Theodore R. Cummins;Joel A. Black;Stephen G. Waxman

  • Contribution of Nav1.8 Sodium Channels to Action Potential Electrogenesis in DRG Neurons

    Muthukrishnan Renganathan;Theodore R. Cummins;Stephen G. Waxman

  • The roles of sodium channels in nociception: Implications for mechanisms of pain

    Theodore R. Cummins;Patrick L. Sheets;Stephen G. Waxman;Stephen G. Waxman

  • Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons

    Sulayman D. Dib-Hajj;Anthony M. Rush;Anthony M. Rush;Theodore Cummins;F. M. Hisama

  • A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons.

    Theodore R. Cummins;Sulayman D. Dib-Hajj;Joel A. Black;Armen N. Akopian

  • Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy

    Theodore R. Cummins;Sulayman D. Dib-Hajj;Sulayman D. Dib-Hajj;Stephen G. Waxman;Stephen G. Waxman

  • A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons

    Anthony M. Rush;Sulayman D. Dib-Hajj;Sulayman D. Dib-Hajj;Shujun Liu;Shujun Liu;Theodore R. Cummins

  • Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain.

    Joel A Black;Shujun Liu;Masaki Tanaka;Theodore R Cummins

  • Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons

    Anthony M. Rush;Theodore R. Cummins;Stephen G. Waxman

  • Sodium channels and pain

    S. G. Waxman;S. Dib-Hajj;T. R. Cummins;J. A. Black

  • The role of sodium channels in chronic inflammatory and neuropathic pain.

    Ron Amir;Charles E. Argoff;Gary J. Bennett;Theodore R. Cummins

  • Slow Closed-State Inactivation: A Novel Mechanism Underlying Ramp Currents in Cells Expressing the hNE/PN1 Sodium Channel

    Theodore R. Cummins;James R. Howe;Stephen G. Waxman;Stephen G. Waxman

  • Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons.

    Raimund I. Herzog;Theodore R. Cummins;Farshid Ghassemi;Sulayman D. Dib-Hajj

  • Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons.

    J. A. Black;T. R. Cummins;T. R. Cummins;C. Plumpton;Y. H. Chen

  • Nav1.3 Sodium Channels: Rapid Repriming and Slow Closed-State Inactivation Display Quantitative Differences after Expression in a Mammalian Cell Line and in Spinal Sensory Neurons

    Theodore R. Cummins;Fabio Aglieco;Mathurkrisnan Renganathan;Raimund I. Herzog

  • SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model

    Masaki Tanaka;Theodore R. Cummins;Theodore R. Cummins;Kuniko Ishikawa;Kuniko Ishikawa;Sulayman D. Dib-hajj;Sulayman D. Dib-hajj

  • Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons.

    R. I. Herzog;Theodore Cummins;S. G. Waxman

  • Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain.

    Sulayman D. Dib-Hajj;Jenny Fjell;Jenny Fjell;Jenny Fjell;Theodore R. Cummins;Theodore R. Cummins;Zheng Zheng

  • From genes to pain: Nav1.7 and human pain disorders

    Sulayman D. Dib-Hajj;Theodore R. Cummins;Joel A. Black;Stephen G. Waxman

  • Comprehensive review The roles of sodium channels in nociception: Implications for mechanisms of pain

    Theodore R. Cummins;Patrick L. Sheets;Stephen G. Waxman

Frequent Co-Authors

Stephen G. Waxman
Stephen G. Waxman Yale University
Sulayman D. Dib-Hajj
Sulayman D. Dib-Hajj Yale University
Joel A. Black
Joel A. Black Yale University
Rajesh Khanna
Rajesh Khanna University of Florida
Jun-Ming Zhang
Jun-Ming Zhang University of Cincinnati Medical Center
Mark Estacion
Mark Estacion Yale University
Kaj Fried
Kaj Fried Karolinska Institute
Harold H. Zakon
Harold H. Zakon The University of Texas at Austin
Louis J. Ptáček
Louis J. Ptáček University of California, San Francisco
Ying-Hui Fu
Ying-Hui Fu University of California, San Francisco

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Theodore R. Cummins

Trending Scientists

Recently Published Articles