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Biology and Biochemistry

D-Index
60
Citations
10658
World Ranking
12145
National Ranking
5194

Overview

Chuan-ju Liu is affiliated with New York University in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research covers a range of topics within these disciplines, with a particular focus on osteoarthritis, cytokine signaling, lysosomal storage disorders, and bone metabolism.

The main fields of study for Chuan-ju Liu include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their subfields of study feature:

  • Molecular Biology
  • Oncology
  • Neurology
  • Physiology
  • Rheumatology

The primary topics in their research include:

  • Osteoarthritis Treatment and Mechanisms
  • Cytokine Signaling Pathways and Interactions
  • Lysosomal Storage Disorders Research
  • Amyotrophic Lateral Sclerosis Research
  • Bone Metabolism and Diseases
  • Inflammatory mediators and NSAID effects
  • Cell Adhesion Molecules Research

Chuan-ju Liu has authored numerous papers, among which recent publications include:

  • Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influx (2022) - Journal of Advanced Research
  • Pathogenic mechanisms of glucocorticoid-induced osteoporosis (2023) - Cytokine & Growth Factor Reviews
  • TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity (2021) - Journal of Clinical Investigation
  • 14-3-3 epsilon is an intracellular component of TNFbib2 receptor complex and its activation protects against osteoarthritis (2021) - Annals of the Rheumatic Diseases
  • Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis (2024) - Nature

The scientist frequently publishes in venues such as:

  • Research Square
  • Bone Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastrointestinal Endoscopy
  • Molecular Genetics and Metabolism

Collaborations have been notable with several researchers, including:

  • Aubryanna Hettinghouse
  • Xiangli Zhao
  • Wenyu Fu
  • Sadaf Hasan
  • Debasis Sahu

Best Publications

  • The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

    Wei Tang;Yi Lu;Yi Lu;Qing-Yun Tian;Yan Zhang

  • Serum interleukin-6 as a marker of periprosthetic infection following total hip and knee arthroplasty.

    Paul E. Di Cesare;Eric Chang;Charles F. Preston;Chuan-ju Liu

  • miR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1.

    Edward A. Lin;Li Kong;Xiao-Hui Bai;Yi Luan

  • ADAMTS-7 Mediates Vascular Smooth Muscle Cell Migration and Neointima Formation in Balloon-Injured Rat Arteries

    Li Wang;Jingang Zheng;Xue Bai;Bo Liu

  • Insights into the role of progranulin in immunity, infection, and inflammation

    Jinlong Jian;Jessica Konopka;Chuanju Liu

  • Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

    Alexandra Zanin-Zhorov;Jonathan M. Weiss;Melanie S. Nyuydzefe;Wei Chen

  • ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein

    Chuan-ju Liu;Wei Kong;Kiril Ilalov;Shuang Yu

  • Calmodulin Binds to the C Terminus of Sodium Channels Nav1.4 and Nav1.6 and Differentially Modulates Their Functional Properties

    Raimund I. Herzog;Chuanju Liu;Stephen G. Waxman;Theodore R. Cummins

  • Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B.

    Chuan ju Liu;Chuan ju Liu;Sulayman D. Dib-Hajj;Sulayman D. Dib-Hajj;Muthukrishnan Renganathan;Muthukrishnan Renganathan;Theodore R. Cummins;Theodore R. Cummins

  • Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin

    Y. Luan;L. Kong;D.R. Howell;K. Ilalov

  • Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling

    Yun-peng Zhao;Ben Liu;Ben Liu;Qing-yun Tian;Jian-lu Wei

  • Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN)

    Chuan-ju Liu;Chuan-ju Liu;Sulayman D. Dib-Hajj;Sulayman D. Dib-Hajj;Stephen G. Waxman;Stephen G. Waxman

  • Cartilage Oligomeric Matrix Protein Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells by Interacting With α7β1 Integrin

    Li Wang;Jingang Zheng;Yaoyao Du;Yaqian Huang

  • Progranulin: a growth factor, a novel TNFR ligand and a drug target.

    Chuan-ju Liu;Xavier Bosch

  • Cartilage Oligomeric Matrix Protein Associates with Granulin-Epithelin Precursor (GEP) and Potentiates GEP-stimulated Chondrocyte Proliferation

    Ke Xu;Yan Zhang;Kirill Ilalov;Cathy S. Carlson

  • Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix protein.

    Fengjin Guo;Yongjie Lai;Qingyun Tian;Edward A. Lin

  • Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis

    Jian Q. Feng;Feng-Jin Guo;Bai-Chun Jiang;Yan Zhang

  • ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.

    Xiao-Hui Bai;Da-Wei Wang;Da-Wei Wang;Li Kong;Yan Zhang

  • ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein.

    Chuan-ju Liu;Chuan-ju Liu;Wei Kong;Ke Xu;Yi Luan;Yi Luan

  • Resistance to HSV-1 Infection in the Epithelium Resides with the Novel Innate Sensor, IFI-16

    Christopher D. Conrady;Min Zheng;Katherine A. Fitzgerald;Chuanju Liu

Frequent Co-Authors

Guozhi Xiao
Guozhi Xiao Southern University of Science and Technology
Peter Lengyel
Peter Lengyel Yale University
Jian Q. Feng
Jian Q. Feng Texas A&M University
Stephen G. Waxman
Stephen G. Waxman Yale University
Cathy S. Carlson
Cathy S. Carlson University of Minnesota
Di Chen
Di Chen Chinese Academy of Sciences
Sulayman D. Dib-Hajj
Sulayman D. Dib-Hajj Yale University
Michael L. Dustin
Michael L. Dustin University of Oxford
Qingbo Xu
Qingbo Xu King's College London
Wei Tang
Wei Tang Chinese Academy of Sciences

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