World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
72
Citations
17487
World Ranking
2123
National Ranking
964

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jacqueline T. Hecht is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research contributions are primarily in the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine.

The scientist's main areas of study include Genetics, Molecular Biology, Pulmonary and Respiratory Medicine, Rheumatology, and Surgery. Their research centers on topics such as Cleft Lip and Palate Research, Craniofacial Disorders and Treatments, Connective Tissue Disorders Research, dental development and anomalies, Osteoarthritis Treatment and Mechanisms, Congenital Ear and Nasal Anomalies, and Genomics and Chromatin Dynamics.

Jacqueline T. Hecht has published extensively, with a notable presence in publication venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics in Medicine
  • Frontiers in Cell and Developmental Biology
  • The American Journal of Human Genetics
  • American Journal of Medical Genetics Part A

The scientist has collaborated frequently with several co-authors, including:

  • Seth M. Weinberg
  • Mary L. Marazita
  • George L. Wehby
  • Elizabeth J. Leslie
  • Carmen J. Buxó

Recent publications demonstrate their research focus and include:

  • "Lifetime impact of achondroplasia: Current evidence and perspectives on the natural history" (2021, Bone)
  • "Genome-wide Enrichment of De Novo Coding Mutations in Orofacial Cleft Trios" (2020, The American Journal of Human Genetics)
  • "Achondroplasia Natural History Study (CLARITY): a multicenter retrospective cohort study of achondroplasia in the United States" (2021, Genetics in Medicine)
  • "Growth in achondroplasia including stature, weight, weight-for-height and head circumference from CLARITY: achondroplasia natural history study-a multi-center retrospective cohort study of achondroplasia in the US" (2021, Orphanet Journal of Rare Diseases)
  • "Genome-Wide Association Study (GWAS) of dental caries in diverse populations" (2021, BMC Oral Health)

Jacqueline T. Hecht is recognized as a Fellow of the American Association for the Advancement of Science (AAAS), an honor awarded in 2018.

Best Publications

  • Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.

    Brendan Lee;Kannan Thirunavukkarasu;Lei Zhou;Lucio Pastore

  • A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia.

    Gary A. Bellus;Iain McIntosh;Iain McIntosh;E. Anne Smith;Arthur S. Aylsworth

  • The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes

    Dominique Stickens;Dominique Stickens;Gregory Clines;David Burbee;Purita Ramos

  • Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia.

    Jacqueline T. Hecht;Laura D. Nelson;Eric Crowder;Yang Wang

  • Natural history study of hereditary multiple exostoses.

    C. L. Wicklund;R. M. Pauli;D. Johnston;Jacqueline T Hecht

  • A type X collagen mutation causes schmid metaphyseal chondrodysplasia

    Matthew L. Warman;Margaret Abbott;Suneel S. Apte;Tim Hefferon

  • A natural history of cleidocranial dysplasia.

    Sara C. Cooper;Catherine M. Flaitz;Dennis A. Johnston;Brendan Lee

  • Genetic heterogeneity in families with hereditary multiple exostoses.

    April Cook;Wendy Raskind;Susan Halloran Blanton;Richard M. Pauli

  • Genetic epidemiology study of idiopathic talipes equinovarus.

    CarolLynn Lochmiller;Dennis Johnston;Allison Scott;Allison Scott;Marjorie Risman

  • CBFA1 Mutation Analysis and Functional Correlation with Phenotypic Variability in Cleidocranial Dysplasia

    Guang Zhou;Yuqing Chen;Lei Zhou;Kannan Thirunavukkarasu

  • Hereditary multiple exostosis and chondrosarcoma: linkage to chromosome II and loss of heterozygosity for EXT-linked markers on chromosomes II and 8.

    Jacqueline T Hecht;Deborah Hogue;Louise C. Strong;Marc F. Hansen

  • Apnea and sudden unexpected death in infants with achondroplasia

    Richard M. Pauli;Charles I. Scott;E. Robert Wassman;Enid F. Gilbert

  • Xeroderma pigmentosum and Cockayne syndrome: overlapping clinical and biochemical phenotypes.

    G. A. Greenhaw;Adelaide A Hebert;M. E. Duke-Woodside;Ian J Butler

  • Mortality in achondroplasia.

    Jacqueline T Hecht;C. A. Francomano;W. A. Horton;J. F. Annegers

  • Essential hypertension vs. secondary hypertension among children

    Monesha Gupta-Malhotra;Ashish Banker;Sanjay Shete;Syed Sharukh Hashmi

  • Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5

    Margaret J McMillin;Anita E Beck;Anita E Beck;Jessica X Chong;Kathryn M Shively

  • A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13

    Elizabeth J Leslie;Jenna C Carlson;John R Shaffer;Eleanor Feingold

  • Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate

    Brett T. Chiquet;Susan H. Blanton;Amber Burt;Deqiong Ma

  • The population-based prevalence of achondroplasia and thanatophoric dysplasia in selected regions of the US.

    D.K. Waller;A. Correa;Tuan M. Vo;Y. Wang

  • Expression of the Heparan Sulfate Proteoglycan, Perlecan, during Mouse Embryogenesis and Perlecan Chondrogenic Activity In Vitro

    M. M. French;S. E. Smith;K. Akanbi;K. Akanbi;T. Sanford

Frequent Co-Authors

Susan H. Blanton
Susan H. Blanton University of Miami
Mary L. Marazita
Mary L. Marazita University of Pittsburgh
Eleanor Feingold
Eleanor Feingold University of Pittsburgh
John B. Mulliken
John B. Mulliken Boston Children's Hospital
William A. Horton
William A. Horton Shriners Hospitals for Children - Erie
Kaare Christensen
Kaare Christensen University of Southern Denmark
Jack Lawler
Jack Lawler Beth Israel Deaconess Medical Center
Jeffrey C. Murray
Jeffrey C. Murray University of Iowa
William G. Cole
William G. Cole University of Toronto
Clair A. Francomano
Clair A. Francomano Indiana University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Genetics in the USA can open doors to a variety of careers in healthcare and scientific research. If you’re looking to expand your options, there are several related online degree programs worth considering.

For those interested in the administrative side of healthcare, there are healthcare administration degree online accredited programs that provide flexibility for working students. If you prefer to accelerate your education, a accelerated healthcare administration degree can help you reach your goals faster.

Individuals keen on direct patient care might explore high acceptance rate nursing programs, which offer accessible entry points into the growing nursing field. Alternatively, those seeking a technical and in-demand role can attain a medical coding and billing certification to begin a career ensuring healthcare data accuracy.

Each of these online pathways can complement a background in Genetics and offer diverse career opportunities in the dynamic healthcare sector.

Best Scientists Citing Jacqueline T. Hecht

Trending Scientists

Recently Published Articles