Ki Churl Chang

Overview

Best Publications

• Heme-oxygenase-1 induction and carbon monoxide-releasing molecule inhibit lipopolysaccharide (LPS)-induced high-mobility group box 1 release in vitro and improve survival of mice in LPS- and cecal ligation and puncture-induced sepsis model in vivo.

  Konstantin Tsoyi;Tae Yu Lee;Young Soo Lee;Hye Jung Kim

  247
  Citations

• The anti-diabetic effect of anthocyanins in streptozotocin-induced diabetic rats through glucose transporter 4 regulation and prevention of insulin resistance and pancreatic apoptosis.

  Irina Tsoy Nizamutdinova;Yong Chun Jin;Jong Il Chung;Sung Chul Shin

  216
  Citations

• Effects of 13-alkyl-substituted berberine alkaloids on the expression of COX-II, TNF-α, iNOS, and IL-12 production in LPS-stimulated macrophages

  Dong Ung Lee;Young Jin Kang;Min Kyu Park;Young Soo Lee

  195
  Citations

• Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats

  K C Chang;S Y Chung;W S Chong;J S Suh

  194
  Citations

• Anthocyanins from soybean seed coat inhibit the expression of TNF‐α‐induced genes associated with ischemia/reperfusion in endothelial cell by NF‐κB‐dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo

  Hye Jung Kim;Irina Tsoy;Jung Min Park;Jong Il Chung

  191
  Citations

• Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic mice

  Konstantin Tsoyi;Hwa Jin Jang;Irina Tsoy Nizamutdinova;Young Min Kim

  190
  Citations

• Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-kappaB signaling pathways.

  Irina Tsoy Nizamutdinova;Hwa Min Oh;Young Nam Min;Sun Hee Park

  171
  Citations

• Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells

  Irina Tsoy Nizamutdinova;Young Min Kim;Jong Il Chung;Sung Chul Shin

  152
  Citations

• Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules

  Irina Tsoy Nizamutdinova;Gyeong Won Lee;Jong Sil Lee;Min Kyung Cho

  148
  Citations

• Anthocyanins from black soybean seed coats inhibit UVB-induced inflammatory cylooxygenase-2 gene expression and PGE2 production through regulation of the nuclear factor-kappaB and phosphatidylinositol 3-kinase/Akt pathway.

  Konstantin Tsoyi;Hyeong Bin Park;Young Min Kim;Jong Il Chung

  141
  Citations

• Daidzein administration in vivo reduces myocardial injury in a rat ischemia/reperfusion model by inhibiting NF-kB activation

  Jong Woo Kim;Yong Chun Jin;Young Min Kim;Sangho Rhie

  135
  Citations

• HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride

  Konstantin Tsoyi;Hye Jung Kim;Jae-Soo Shin;Dal-Hyun Kim

  133
  Citations

• Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage

  Eun Sil Kang;Im Sun Woo;Hyo Jung Kim;So Young Eun

  130
  Citations

• Tanshinone I effectively induces apoptosis in estrogen receptor-positive (MCF-7) and estrogen receptor-negative (MDA-MB-231) breast cancer cells

  Irina Tsoy Nizamutdinova;Gyeong Won Lee;Kun Ho Son;Su Jin Jeon

  127
  Citations

• Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro.

  Jae Ju Jeong;Yu Mi Ha;Yong Chun Jin;Eun Ju Lee

  123
  Citations

• 2-methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction.

  Jeong Seok Hwa;Yong Chun Jin;Young Soo Lee;Young Shin Ko

  122
  Citations

• Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. reduces inflammation in LPS-activated RAW 264.7 cells and CLP-induced septic mice.

  Eun Jung Park;Young Min Kim;Sang Won Park;Hye Jung Kim

  117
  Citations

• Cryptotanshinone, a lipophilic compound of Salvia miltiorrriza root, inhibits TNF-α-induced expression of adhesion molecules in HUVEC and attenuates rat myocardial ischemia/reperfusion injury in vivo.

  Yong Chun Jin;Chun Wook Kim;Young Min Kim;Irina Tsoy Nizamutdinova

  114
  Citations

• Palmatine from Coptidis rhizoma reduces ischemia–reperfusion-mediated acute myocardial injury in the rat

  Young Min Kim;Yu Mi Ha;Yong Chun Jin;Lian Yu Shi

  113
  Citations

• Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats.

  Irina Tsoy Nizamutdinova;Yong Chun Jin;Ju Sun Kim;Min Hye Yean

  112
  Citations