World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
105
Citations
40486
World Ranking
6776
National Ranking
3576

Overview

Alfred L. George is a researcher affiliated with Northwestern University in the United States. Their work spans multiple disciplines within the life sciences, with a strong focus on molecular biology, genetics, and medicine.

The scientist's recent research publications cover a variety of topics and venues, including:

  • "Negligible-Cost and Weekend-Free Chemically Defined Human iPSC Culture" (2020) published in Stem Cell Reports
  • "Precision medicine for genetic epilepsy on the horizon: Recent advances, present challenges, and suggestions for continued progress" (2022) published in Epilepsia
  • "A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia" (2021) published in American Journal of Obstetrics and Gynecology
  • "Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls" (2022) published in Stem Cell Reports
  • "High-throughput evaluation of epilepsy-associated KCNQ2 variants reveals functional and pharmacological heterogeneity" (2022) published in JCI Insight

Their research includes collaboration with several frequent coauthors, notably:

  • Carlos G. Vanoye
  • Christopher H. Thompson
  • Jean-Marc DeKeyser
  • Charles R. Sanders
  • Elizabeth M. McNally

Alfred L. George has published extensively in several prominent venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • eLife
  • Neurobiology of Disease
  • Circulation Research

The researcher has contributed to book publications released by Cambridge University Press, with titles such as:

  • KCNQ2- and KCNQ3-Associated Epilepsy (2022)
  • How We Got to Where We're Going (2021)

Alfred L. George's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields of study cover areas such as:

  • Molecular Biology
  • Cardiology and Cardiovascular Medicine
  • Cellular and Molecular Neuroscience
  • Genetics
  • Psychiatry and Mental Health

The primary research topics addressed by George include:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Neuroscience and Neuropharmacology Research
  • Neuroscience and Neural Engineering
  • Genetics and Neurodevelopmental Disorders
  • Genomics and Rare Diseases
  • Epilepsy research and treatment

Best Publications

  • Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.

    Robyn H. Wallace;Dao W. Wang;Rita Singh;Rita Singh;Ingrid E. Scheffer;Ingrid E. Scheffer;Ingrid E. Scheffer

  • Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome

    Nikki M. Plaster;Rabi Tawil;Martin Tristani-Firouzi;Sonia Canún

  • Molecular mechanism for an inherited cardiac arrhythmia

    Paul B. Bennett;Kazuto Yazawa;Naomasa Makita;Alfred L. George

  • Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel

    Mary E. Gellens;Alfred L. George;Liqiong Chen;Mohamed Chahine

  • Molecular Basis of Charge Movement in Voltage-Gated Sodium Channels

    Naibo Yang;Alfred L George;Richard Horn

  • Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)

    D. Woodrow Benson;Dao W. Wang;Macaira Dyment;Timothy K. Knilans

  • Allelic Variants in Long-QT Disease Genes in Patients With Drug-Associated Torsades de Pointes

    Ping Yang;Hideaki Kanki;Benoit Drolet;Tao Yang

  • Prevalence of Long-QT Syndrome Gene Variants in Sudden Infant Death Syndrome

    Marianne Arnestad;Lia Crotti;Torleiv O. Rognum;Roberto Insolia

  • A common polymorphism associated with antibiotic-induced cardiac arrhythmia

    Federico Sesti;Geoffrey W. Abbott;Jian Wei;Katherine T. Murray

  • PiggyBac Transposon-Mediated Gene Transfer in Human Cells

    Matthew H Wilson;Craig J Coates;Alfred L George

  • Identification of a mutation in the gene causing hyperkalemic periodic paralysis.

    Louis J. Ptáček;Alfred L. George;Robert C. Griggs;Rabi Tawil

  • Neuronal Sodium-Channel α1-Subunit Mutations in Generalized Epilepsy with Febrile Seizures Plus

    R.H. Wallace;R.H. Wallace;I.E. Scheffer;S. Barnett;M. Richards

  • Inherited disorders of voltage-gated sodium channels

    Alfred L. George

  • Calmodulin mutations associated with recurrent cardiac arrest in infants

    Lia Crotti;Christopher N. Johnson;Elisabeth Graf;Gaetano M. De Ferrari

  • Molecular Basis of an Inherited Epilepsy

    Christoph Lossin;Dao W. Wang;Thomas H. Rhodes;Carlos G. Vanoye

  • Cardiac Ion Channels

    Dan M. Roden;Jeffrey R. Balser;Alfred L. George;Mark E. Anderson

  • Cardiac Sodium Channel (SCN5A) Variants Associated with Atrial Fibrillation

    Dawood Darbar;Prince J. Kannankeril;Brian S. Donahue;Gayle Kucera

  • Sodium Channel Mutations in Paramyotonia Congenita Uncouple Inactivation from Activation

    Mohamed Chahine;Alfred L. George;Ming Zhou;Sen Ji

  • Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (bo,+AT) of rBAT.

    Lídia Feliubadaló;Mariona Font;Jesús Purroy;Ferran Rousaud

  • Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's Syndrome

    N Plaster;R Tawil;M Tristani-Firouzi;S Canun

Frequent Co-Authors

Peter J. Schwartz
Peter J. Schwartz Istituto Auxologico Italiano
Dan M. Roden
Dan M. Roden Vanderbilt University Medical Center
Charles R. Sanders
Charles R. Sanders Vanderbilt University
Jens Meiler
Jens Meiler Vanderbilt University
Jennifer A. Kearney
Jennifer A. Kearney Northwestern University
Christoph Fahlke
Christoph Fahlke Forschungszentrum Jülich
Walter J. Chazin
Walter J. Chazin Vanderbilt University
D. Woodrow Benson
D. Woodrow Benson Medical College of Wisconsin
Connie R. Bezzina
Connie R. Bezzina University of Amsterdam
Louis J. Ptáček
Louis J. Ptáček University of California, San Francisco

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Not everyone chooses the traditional path to a medical career. Many students explore alternate and online healthcare degrees that offer flexibility and faster entry into the workforce. For those seeking nursing careers, you may want to consider some of the easiest rn program options, which can be less competitive and more accessible.

Prospective nurses who wish to bypass lengthy admissions procedures might prefer a nursing school no entrance exam requirement, helping to streamline the enrollment process. Those interested in non-clinical roles can look into online medical billing and coding schools that accept fafsa, which offer sought-after programs eligible for financial aid.

If you're aiming to advance quickly, explore accelerated healthcare programs that let you earn a degree in less time. These varied pathways can open doors to rewarding healthcare careers, making it easier to match your education to your personal and professional goals.

Best Scientists Citing Alfred L. George

Trending Scientists