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Frank Lehmann-Horn

Frank Lehmann-Horn

D-Index & Metrics

Medicine

D-Index
85
Citations
20754
World Ranking
14788
National Ranking
783

Overview

Frank Lehmann-Horn was affiliated with the University of Ulm in Germany. Their research contributions primarily focused on biochemistry, genetics, molecular biology, neuroscience, and medicine, with a notable emphasis on molecular biology, cellular and molecular neuroscience, and cardiology and cardiovascular medicine.

The scientist's work concentrated on topics including ion channel regulation and function, genetic neurodegenerative diseases, cardiac electrophysiology and arrhythmias, biochemical and molecular research, as well as neuroscience and neuropharmacology research.

Frequent co-authors who collaborated with Lehmann-Horn included Karin Jurkat-Rott, Kerstin Hoppe, Sunisa Chaiklieng, Scott Wearing, and Werner Klingler.

Key recent publications featured the following papers:

  • Confirmation of the Type 2 Myotonic Dystrophy (CCTG)n Expansion Mutation in Patients with Proximal Myotonic Myopathy/Proximal Myotonic Dystrophy of Different European Origins: A Single Shared Haplotype Indicates an Ancestral Founder Effect, 2020, UNC Libraries
  • Paxilline Prevents the Onset of Myotonic Stiffness in Pharmacologically Induced Myotonia: A Preclinical Investigation, 2020, Frontiers in Physiology
  • Preclinical pharmacological in vitro investigations on low chloride conductance myotonia: effects of potassium regulation, 2020, Pflügers Archiv - European Journal of Physiology
  • Correction to: Preclinical pharmacological in vitro investigations on low chloride conductance myotonia: effects of potassium regulation, 2020, Pflügers Archiv - European Journal of Physiology
  • Markov and Eyring Modeling Predict Differential Contributions of Homologous Mutations in Hypokalemic Periodic Paralysis to Skeletal Muscle Fiber Excitability, 2021, Biophysical Journal

Lehmann-Horn published frequently in venues such as Pflügers Archiv - European Journal of Physiology, Frontiers in Physiology, UNC Libraries, and Biophysical Journal.

Best Publications

  • The skeletal muscle chloride channel in dominant and recessive human myotonia.

    Manuela C. Koch;Klaus Steinmeyer;Claudius Lorenz;Kenneth Ricker

  • Voltage-Gated Ion Channels and Hereditary Disease

    Frank Lehmann-Horn;Karin Jurkat-Rott

  • Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2.

    T. V. Mccarthy;J. M. S. Healy;J. J. A. Heffron;M. Lehane

  • GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak

    Yvonne G. Weber;Alexander Storch;Thomas V. Wuttke;Knut Brockmann

  • A calcium channel mutation causing hypokalemic periodic paralysis

    Karln Jurkat-Rott;Frank Lehmann-Horn;Alexis Elbaz;Roland Heine

  • Genetics and pathogenesis of malignant hyperthermia.

    Karin Jurkat-Rott;Tommie McCarthy;Frank Lehmann-Horn

  • In vitro contracture test for diagnosis of malignant hyperthermia following the protocol of the European MH Group: Results of testing patients surviving fulminant MH and unrelated low-risk subjects

    H. Ørding;V. Brancadoro;S. Cozzolino;F. R. Ellis

  • Active fascial contractility: Fascia may be able to contract in a smooth muscle-like manner and thereby influence musculoskeletal dynamics

    R. Schleip;W. Klingler;F. Lehmann-Horn

  • Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia).

    Nicole S;Davoine Cs;Topaloglu H;Cattolico L

  • Proximal myotonic myopathy: a new dominant disorder with myotonia, muscle weakness, and cataracts.

    K. Ricker;M. C. Koch;F. Lehmann-Horn;D. Pongratz

  • Voltage-sensor Sodium Channel Mutations Cause Hypokalemic Periodic Paralysis Type 2 by Enhanced Inactivation and Reduced Current

    Karin Jurkat-Rott;Nenad Mitrovic;Chao Hang;Alexei Kouzmenkine

  • Mapping of the hypokalaemic periodic paralysis (HypoPP) locus to chromosome 1q31-32 in three European families

    Fontaine B;Vale-Santos J;Jurkat-Rott K;Reboul J

  • Adynamia episodica hereditaria with myotonia: a non-inactivating sodium current and the effect of extracellular pH

    Frank Lehmann‐Horn;Gerald Küther;Kenneth Ricker;Peter Grafe

  • Hypokalaemic periodic paralysis type 2 caused by mutations at codon 672 in the muscle sodium channel gene SCN4A.

    Damien Sternberg;Thierry Maisonobe;Karin Jurkat-Rott;Sophie Nicole

  • Hypokalemic periodic paralysis: in vitro investigation of muscle fiber membrane parameters.

    Reinhardt Rüdel;Frank Lehmann‐Horn;Kenneth Ricker;Gerald Küther

  • Passive muscle stiffness may be influenced by active contractility of intramuscular connective tissue

    Robert Schleip;Ian L. Naylor;Daniel Ursu;Werner Melzer

  • Overexcited or inactive: Ion channels in muscle disease

    Eric P Hoffman;Frank Lehmann-Horn;Reinhardt Rädel

  • The role of fibrosis in Duchenne muscular dystrophy.

    Werner Klingler;Karin Jurkat-Rott;Frank Lehmann-Horn;Robert Schleip

  • Ion channels and epilepsy.

    Holger Lerche;Karin Jurkat-Rott;Frank Lehmann-Horn

  • Variability of familial hemiplegic migraine with novel A1A2 Na+/K+-ATPase variants.

    K. Jurkat-Rott;T. Freilinger;J. P. Dreier;J. Herzog

Frequent Co-Authors

Holger Lerche
Holger Lerche University of Tübingen
Bertrand Fontaine
Bertrand Fontaine Université Paris Cité
Reinhard Dengler
Reinhard Dengler Hanover University of Applied Sciences and Arts
Peter Grafe
Peter Grafe Ludwig-Maximilians-Universität München
Alfred L. George
Alfred L. George Northwestern University
Marco Essig
Marco Essig University of Manitoba
Paola Giunti
Paola Giunti University College London
Yvonne G. Weber
Yvonne G. Weber University of Tübingen
Jean Weissenbach
Jean Weissenbach Centre national de la recherche scientifique, CNRS
Alexis Elbaz
Alexis Elbaz Versailles Saint-Quentin-en-Yvelines University

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