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Biology and Biochemistry

D-Index
63
Citations
15849
World Ranking
10125
National Ranking
285

Overview

Michael Pusch is affiliated with the National Research Council (CNR) in Italy. Their research primarily spans the disciplines of Biochemistry, Genetics and Molecular Biology, with a significant focus also on Medicine. Within these fields, their work delves into subfields including Molecular Biology, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience, Physiology, and Sensory Systems.

Their publications cover a range of topics, notably:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Nicotinic Acetylcholine Receptors Study
  • Neuroscience and Neuropharmacology Research
  • Ion Channels and Receptors
  • Ion Transport and Channel Regulation
  • Cellular transport and secretion

Michael Pusch has published frequently in notable scientific journals. These publication venues include:

  • Biophysical Journal
  • Life
  • International Journal of Molecular Sciences
  • The Journal of Physiology
  • The FASEB Journal

Examples of their recent scientific papers are:

  • Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model, 2021, Journal of Clinical Investigation
  • Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7-related osteopetrosis, 2020, Journal of Bone and Mineral Research
  • Voltage-Gated Sodium Channel Dysfunctions in Neurological Disorders, 2023, Life
  • An Up-to-Date Overview of the Complexity of Genotype-Phenotype Relationships in Myotonic Channelopathies, 2020, Frontiers in Neurology
  • Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders, 2021, The American Journal of Human Genetics

Their frequent coauthors reflect collaborations across various scientific areas. These include:

  • Paola Gavazzo
  • Raffaella Barbieri
  • Sara Bertelli
  • Alessia Remigante
  • Paolo Zuccolini

Best Publications

  • Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.

    Martin Dichgans;Tobias Freilinger;Gertrud Eckstein;Elena Babini

  • Rates of diffusional exchange between small cells and a measuring patch pipette.

    Michael Pusch;Erwin Neher

  • A chloride channel widely expressed in epithelial and non-epithelial cells.

    Astrid Thiemann;Stefan Gründer;Michael Pusch;Thomas J. Jentsch

  • Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.

    Heinrich Terlau;Stefan H. Heinemann;Walter Stühmer;Michael Pusch

  • Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5

    Alessandra Picollo;Michael Pusch

  • Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume.

    Stefan Gründer;Astrid Thiemann;Michael Pusch;Thomas J. Jentsch

  • CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease.

    Thomas J. Jentsch;Michael Pusch

  • Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion

    Michael Pusch;Uwe Ludewig;Annett Rehfeldt;Thomas J. Jentsch

  • Two physically distinct pores in the dimeric ClC-0 chloride channel.

    Uwe Ludewig;Michael Pusch;Thomas J. Jentsch

  • Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.

    Anne Schenzer;Thomas Friedrich;Michael Pusch;Paul Saftig

  • Heteromultimeric CLC chloride channels with novel properties

    Claudius Lorenz;Michael Pusch;Thomas J. Jentsch

  • Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen).

    K Steinmeyer;C Lorenz;M Pusch;M C Koch

  • Properties of voltage-gated chloride channels of the ClC gene family.

    T J Jentsch;W Günther;M Pusch;B Schwappach

  • Myotonia caused by mutations in the muscle chloride channel gene CLCN1

    Michael Pusch

  • Biophysical properties of acid-sensing ion channels (ASICs).

    Stefan Gründer;Michael Pusch

  • Mutations in dominant human myotonia congenita drastically alter the voltage dependence of the CIC-1 chloride channel

    Michael Pusch;Klaus Steinmeyer;Manuela C. Koch;Thomas J. Jentsch

  • The Muscle Chloride Channel ClC-1 Has a Double-Barreled Appearance that Is Differentially Affected in Dominant and Recessive Myotonia

    Chiara Saviane;Franco Conti;Michael Pusch

  • Surface Expression and Single Channel Properties of KCNQ2/KCNQ3, M-type K+ Channels Involved in Epilepsy

    Michael Schwake;Michael Pusch;Tatjana Kharkovets;Thomas J. Jentsch

  • Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.

    Raúl Estévez;Björn C Schroeder;Alessio Accardi;Thomas J Jentsch

  • Multimeric structure ofCIC-1chloride channel revealed bymutations indominant myotonia congenita (Thomsen)

    Claudius Lorenz;Michael Pusch

Frequent Co-Authors

Thomas J. Jentsch
Thomas J. Jentsch Charité - University Medicine Berlin
Uwe Ludewig
Uwe Ludewig University of Hohenheim
Martin Dichgans
Martin Dichgans Ludwig-Maximilians-Universität München
Walter Stühmer
Walter Stühmer Max Planck Society
Michael C. Sanguinetti
Michael C. Sanguinetti University of Utah
Reinhold Penner
Reinhold Penner Queen's Medical Center
Shosaku Numa
Shosaku Numa Kyoto University
Michel D. Ferrari
Michel D. Ferrari Leiden University Medical Center
Arn M. J. M. van den Maagdenberg
Arn M. J. M. van den Maagdenberg Leiden University Medical Center
Tim M. Strom
Tim M. Strom Technical University of Munich

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